MIMIC - Do parasitic worms and their secreted immunomudulators protect against musculosketal disease by impacting on the host microbiome?

Project: Research

Project Details

StatusFinished
Effective start/end date1/10/1530/06/18

Funding

  • Arthritis Research UK ARUK: £180,846.00

Research Output

The parasitic worm product ES-62 normalises the gut microbiota bone marrow axis in inflammatory arthritis

Doonan, J., Tarafdar, A., Pineda, M. A., Lumb, F. E., Crowe, J., Khan, A. M., Hoskisson, P. A., Harnett, M. M. & Harnett, W., 5 Apr 2019, In : Nature Communications. 10, 14 p., 1554.

Research output: Contribution to journalArticle

Open Access
File
  • 10 Citations (Scopus)
    13 Downloads (Pure)

    Protection against arthritis by the parasitic worm product ES-62, and its drug-like small molecule analogues, is associated with inhibition of osteoclastogenesis

    Doonan, J., Lumb, F. E., Pineda, M. A., Tarafdar, A., Crowe, J., Khan, A. M., Suckling, C. J., Harnett, M. M. & Harnett, W., 14 May 2018, In : Frontiers in Immunology. 9, 13 p., 1016.

    Research output: Contribution to journalArticle

    Open Access
    File
    11 Citations (Scopus)
    39 Downloads (Pure)