MIMIC - Do parasitic worms and their secreted immunomudulators protect against musculosketal disease by impacting on the host microbiome?

Harnett, William (Principal Investigator)
Hoskisson, Paul (Co-investigator)

Project: Research

Description

MIMIC - Do parasitic worms and their secreted immunomudulators protect against musculosketal disease by impacting on the host microbiome?

Status	Finished
Effective start/end date	1/10/15 → 30/06/18

Funding

Versus Arthritis (formerly Arthritis Research UK ARUK): £180,846.00

2 Article

The parasitic worm product ES-62 normalises the gut microbiota bone marrow axis in inflammatory arthritis
Doonan, J., Tarafdar, A., Pineda, M. A., Lumb, F. E., Crowe, J., Khan, A. M., Hoskisson, P. A., Harnett, M. M. & Harnett, W., 5 Apr 2019, In: Nature Communications. 10, 14 p., 1554.
Research output: Contribution to journal › Article › peer-review

Open Access
File
52 Citations (Scopus)

48 Downloads (Pure)
Protection against arthritis by the parasitic worm product ES-62, and its drug-like small molecule analogues, is associated with inhibition of osteoclastogenesis
Doonan, J., Lumb, F. E., Pineda, M. A., Tarafdar, A., Crowe, J., Khan, A. M., Suckling, C. J., Harnett, M. M. & Harnett, W., 14 May 2018, In: Frontiers in Immunology. 9, 13 p., 1016.
Research output: Contribution to journal › Article › peer-review

Open Access
File
33 Citations (Scopus)

75 Downloads (Pure)