Factors associated with the prescribing of direct acting oral anticoagulant drugs and the impact of the COVID-19 pandemic on the prescribing of these drugs: A Scoping Review

Project: Research

Project Details

Description

Direct-Acting Oral Anticoagulants (DOACs) – apixaban, dabigatran, edoxaban, and rivaroxaban – have emerged and are being used as alternatives to vitamin k antagonists for the prevention and treatment of different cardiovascular conditions (1,2). Since the DOACs first approval in the UK in 2008 (3), they have become the preferred choice for anticoagulation, because of their documented non-inferior efficacy and safety in large randomized prospective trials and real-world observational studies, and because of their much more convenience to use (4-6). With the rapid uptake of DOACs, prescribers are faced with increasingly complex decisions relating to appropriate agent and appropriate dose to be prescribed (7). This review will explore and provide an overview of the factors influencing the prescribing of DOACs in general.
Short titlescoping review protocol
StatusFinished
Effective start/end date2/01/2329/12/23

Keywords

  • (Anticoagulants; Anticoagulant agent, anticoagulant drug, oral anticoagulation, Direct thrombin inhibitor, Factor Xa inhibitors, Apixaban; Dabigatran; Edoxaban; Rivaroxaban; prescribing trends; prescribing pattern; factors affecting prescribing; Prescribing data, Drug prescription, Drug utilisation, Treatment decision making, Drug choice, Prescribing behaviour)

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