EC-FP7-HEALTH-2013-INNOVATION-1: Understanding chronic pain and new druggable targets: Focus on glial-opioid receptor interface (GLORIA)

Moreira, Vania (Research Co-investigator)
Ruff-Gaveriaux, Claire (Co-investigator)
Yli-Kauhaluoma, Jari Tapani (Co-investigator)
Airavaara, Mikko (Co-investigator)
Ahonen, Tiina (Post Grad Student)
Xhaard, Henri (Co-investigator)
Kalso, Eija (Principal Investigator)
Saarma, Mart (Co-investigator)

Strathclyde Institute Of Pharmacy And Biomedical Sciences

Project: Projects from Previous Employment

Status	Finished
Effective start/end date	1/11/13 → 31/10/18

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Mitoxantrone, pixantrone, and mitoxantrone (2-hydroxyethyl)piperazine are toll-like receptor 4 antagonists, inhibit NF-κB activation, and decrease TNF-alpha secretion in primary microglia
Rinne, M., Mätlik, K., Ahonen, T., Vedovi, F., Zappia, G., Moreira, V., Yli-Kauhaluoma, J., Leino, S., Salminen, O., Kalso, E., Airavaara, M. & Xhaard, H., 1 Nov 2020, In: European Journal of Pharmaceutical Sciences. 154, 105493.
Research output: Contribution to journal › Article › peer-review

Open Access
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12 Citations (Scopus)

14 Downloads (Pure)
Synthesis of 7β-hydroxy-8-ketone opioid derivatives with antagonist activity at the mu- and delta- opioid receptors
Ahonen, T. J., Rinne, M., Grutschreiber, P., Mätlik, K., Airavaara, M., Schaarschmidt, D., Lang, H., Reiss, D., Xhaard, H., Gavériaux-Ruff, C., Yli-Kauhaluoma, J. & Moreira, V. M., 10 May 2018, In: European Journal of Medicinal Chemistry. 151, p. 495-507 13 p.
Research output: Contribution to journal › Article › peer-review

Open Access
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3 Citations (Scopus)

46 Downloads (Pure)