Computationally Designed Templates for Exquisite Control of Polymorphic Form

Florence, Alastair (Principal Investigator)
Lamprou, Dimitrios (Co-investigator)

Strathclyde Institute Of Pharmacy And Biomedical Sciences

Project: Research

Project Details

Status	Finished
Effective start/end date	1/10/13 → 30/06/18

Funding

EPSRC (Engineering and Physical Sciences Research Council): £374,902.19

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4 Article

Reversible two-step single-crystal to single-crystal phase transitions between desloratadine forms I, II and III
Srirambhatla, V. K., Guo, R., Dawson, D. M., Price, S. L. & Florence, A. J., 4 Mar 2020, In : Crystal Growth and Design. 20, 3, p. 1800-1810 11 p.
Research output: Contribution to journal › Article

Open Access
File
6 Citations (Scopus)

1 Downloads (Pure)
Enabling precision manufacturing of active pharmaceutical ingredients: workflow for seeded cooling continuous crystallisations
Brown, C. J., McGlone, T., Yerdelen, S., Srirambhatla, V., Mabbott, F., Gurung, R., Briuglia, M. L., Ahmed, B., Polyzois, H., McGinty, J., Perciballi, F., Fysikopoulos, D., Macfhionnghaile, P., Siddique, H., Raval, V., Harrington, T. S., Vassileiou, A. D., Robertson, M., Prasad, E., Johnston, A. & 9 others, Johnston, B., Nordon, A., Srai, J. S., Halbert, G., ter Horst, J. H., Price, C. J., Rielly, C. D., Sefcik, J. & Florence, A. J., 1 Jun 2018, In : Molecular Systems Design & Engineering. 2018, 3, p. 518-549 32 p.
Research output: Contribution to journal › Article

Open Access
File
29 Citations (Scopus)

83 Downloads (Pure)
Direct observation of templated two-step nucleation mechanism during olanzapine hydrate formation
Warzecha, M., Guo, R., Bhardwaj, R. M., Reutzel-Edens, S. M., Price, S. L., Lamprou, D. A. & Florence, A. J., 23 Oct 2017, In : Crystal Growth and Design. 17, 12, p. 6382-6393 12 p.
Research output: Contribution to journal › Article

Open Access
File
20 Citations (Scopus)

15 Downloads (Pure)

Data for: "Reversible, Two-Step Single-Crystal to Single-Crystal Phase Transitions between Desloratadine Forms I, II, and III"
Srirambhatla, V. (Creator), Guo, R. (Contributor), Dawson, D. (Contributor), Price, S. (Contributor) & Florence, A. (Owner), University of Strathclyde, 18 Mar 2020
DOI: 10.15129/b41246a8-eaf7-4d91-ac55-eceb02a2a5ac
Dataset

Computationally Designed Templates for Exquisite Control of Polymorphic Form

Funding

Reversible two-step single-crystal to single-crystal phase transitions between desloratadine forms I, II and III

Enabling precision manufacturing of active pharmaceutical ingredients: workflow for seeded cooling continuous crystallisations

Direct observation of templated two-step nucleation mechanism during olanzapine hydrate formation

Data for: "Reversible, Two-Step Single-Crystal to Single-Crystal Phase Transitions between Desloratadine Forms I, II, and III"