Chance and Necessity: Evolution guided antibiotic improvement and discovery

Research output

Research output per year 2020 2022 2023

• 5 Article
• 1 Chapter

Research output per year

Research output per year

Search results

• 2023

  On the evolution of natural product biosynthesis

  Barona-Gómez, F., Chevrette, M. G. & Hoskisson, P. A., 19 Apr 2023, (Accepted/In press) Advances in Microbial Physiology. Amsterdam, 56 p. (Advances in Microbial Physiology ).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Biological Products 100%
  • Multigene Family 55%
  • Secondary Metabolism 39%
  • Developmental Biology 33%
  • Ecology 30%
• 2022

  Intra-colony channel morphology in Escherichia coli biofilms is governed by nutrient availability and substrate stiffness

  Bottura, B., Rooney, L. M., Hoskisson, P. A. & McConnell, G., 31 Dec 2022, In: Biofilm. 4, 14 p., 100084.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Biofilms 100%
  • Nutrients 87%
  • Escherichia coli 71%
  • Carbon 16%
  • Nitrogen 16%
  2 Citations (Scopus)

  7 Downloads (Pure)

• Biosynthesis of aurodox, a Type III secretion system inhibitor from Streptomyces goldiniensis

  McHugh, R. E., Munnoch, J. T., Braes, R. E., McKean, I. J. W., Giard, J., Taladriz-Sender, A., Peschke, F., Burley, G. A., Roe, A. J. & Hoskisson, P. A., 9 Aug 2022, In: Applied and Environmental Microbiology. 88, 15, 11 p., e00692-22.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Aurodox 100%
  • Type III Secretion Systems 61%
  • type III secretion system 58%
  • Streptomyces 56%
  • biosynthesis 51%
  2 Citations (Scopus)

  10 Downloads (Pure)

• ActinoBase: tools and protocols for researchers working on Streptomyces and other filamentous actinobacteria

  Feeney, M. A., Newitt, J. T., Addington, E., Algora-Gallardo, L., Allan, C., Balis, L., Birke, A. S., Castaño-Espriu, L., Charkoudian, L. K., Devine, R., Gayrard, D., Hamilton, J., Hennrich, O., Hoskisson, P. A., Keith-Baker, M., Klein, J. G., Kruasuwan, W., Mark, D. R., Mast, Y., McHugh, R. E., & 24 othersMcLean, T. C., Mohit, E., Munnoch, J. T., Murray, J., Noble, K., Otani, H., Parra, J., Pereira, C. F., Perry, L., Pintor-Escobar, L., Pritchard, L., Prudence, S. M. M., Russell, A. H., Schniete, J. K., Seipke, R. F., Sélem-Mojica, N., Undabarrena, A., Vind, K., van Wezel, G. P., Wilkinson, B., Worsley, S. F., Duncan, K. R., Fernández-Martínez, L. T. & Hutchings, M. I., 1 Jul 2022, In: Microbial Genomics. 8, 7, 11 p., 000824.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Actinobacteria 100%
  • Streptomyces 96%
  • Research Personnel 54%
  • Bacteria 26%
  • Ecology 23%
  17 Downloads (Pure)

• Genome sequence of the aurodox-producing bacterium Streptomyces goldiniensis ATCC 21386

  McHugh, R. E., Munnoch, J. T., Roe, A. J. & Hoskisson, P. A., 30 May 2022, In: Access Microbiology . 4, 5, 5 p., 000358.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Aurodox 100%
  • Streptomyces 56%
  • Genome 31%
  • Bacteria 30%
  • Nucleic Acid Databases 21%
  4 Downloads (Pure)
• 2020

  Cryptic or silent? The known unknowns, unknown knowns, and unknown unknowns of secondary metabolism

  Hoskisson, P. A. & Seipke, R. F., 20 Oct 2020, In: mBio. 11, 5, 5 p., e02642-20.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Secondary Metabolism 100%
  • Anti-Bacterial Agents 42%
  • Actinobacteria 41%
  • Biological Products 31%
  • Biosynthetic Pathways 19%
  24 Citations (Scopus)

  21 Downloads (Pure)