Can studying the mechanism of action of the parasitic worm-derived immunomodulator ES-62, inform on how to slow ageing and improve healthspan?

Harnett, William (Principal Investigator)

Strathclyde Institute Of Pharmacy And Biomedical Sciences

Project: Research

2 Article

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2019
Synthetic small molecule analogues of the immunomodulatory Acanthocheilonema viteae product ES-62 promote metabolic homeostasis during obesity in a mouse model
Lumb, F. E., Crowe, J., Doonan, J., Suckling, C. J., Selman, C., Harnett, M. M. & Harnett, W., 31 Dec 2019, In: Molecular and Biochemical Parasitology. 234, 13 p., 111232.
Research output: Contribution to journal › Article › peer-review

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6 Citations (Scopus)

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2018
Protection against arthritis by the parasitic worm product ES-62, and its drug-like small molecule analogues, is associated with inhibition of osteoclastogenesis
Doonan, J., Lumb, F. E., Pineda, M. A., Tarafdar, A., Crowe, J., Khan, A. M., Suckling, C. J., Harnett, M. M. & Harnett, W., 14 May 2018, In: Frontiers in Immunology. 9, 13 p., 1016.
Research output: Contribution to journal › Article › peer-review

Open Access
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25 Citations (Scopus)

52 Downloads (Pure)