The aim of this project is to develop novel and high-throughput methodologies for anti-cancer drug discovery using droplet-based, microfluidic systems. This will enable cells from a patient’s tumour to be used in tests for new drugs in a reproducible and cost-effective manner. By combining microfluidic engineering with cell-biology, we aim to develop a unique microfluidic system for analysing drug effects on single-cells and cell-clusters as opposed to existing technology that requires 100,000 cells for each experiment. By exploiting the compartmentalisation capabilities of microdroplet technology and the functionalities of microfluidics, we will explore novel technological alternatives to conventional cancer cell research.
|Effective start/end date||1/01/12 → …|