This experimental-computational project will investigate peptoids, a new class of peptide-inspired polymers, as novel biomimetic surface coatings. Although peptides are remarkable natural polymers that can perform complex biological functions, it is difficult to design or predict their properties. Peptoids mimic the chemical structure and functionality of peptides but have simplified chemical synthesis and unprecedented properties. As a first step, we aim to design model peptoids that can adsorb on surfaces by studying the solubility of peptoids, a fundamental property that determines their physical behaviour and biofunctionality. This will pave the way to fabricating highly functional materials for advanced coating applications.
|Effective start/end date||17/03/14 → 15/08/14|