Research output per year
Research output per year
Project Details
Description
Accelerated Discovery and Development of New Medicines: Prosperity Partnership for a Healthier Nation
| Status | Finished |
|---|---|
| Effective start/end date | 1/01/19 → 30/09/24 |
Funding
- EPSRC (Engineering and Physical Sciences Research Council): £5,495,022.00
- EPSRC (Engineering and Physical Sciences Research Council): £97,716.00
Fingerprint
Explore the research topics touched on by this project. These labels are generated based on the underlying awards/grants. Together they form a unique fingerprint.
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BET isoform selectivity through diverse linkers for bivalent inhibitors: GSK785, a BRD2/4-selective bivalent BET inhibitor
Rianjongdee, F., Atkinson, S. J., Bamborough, P., Barnett, H. A., Friston, K., Grandi, P., Neipp, C. E., Petretich, M., Phillipou, A., Preston, A. G. S., Prinjha, R. K., Tomkinson, N. C. O. & Demont, E. H., 30 Dec 2025, (E-pub ahead of print) In: Journal of Medicinal Chemistry. 23 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
A convergent radical cascade for the synthesis of azaindanes
Grace, C. D., Murphy, J. A. & Nicolle, S. M., 5 Sept 2025, In: Chemistry - A European Journal. 31, 50, 10 p., e01908.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Physics-based solubility prediction for organic molecules
Fowles, D. J., Connaughton, B. J., Carter, J. W., Mitchell, J. B. O. & Palmer, D. S., 13 Aug 2025, In: Chemical Reviews. 125, 15, p. 7057-7098 42 p.Research output: Contribution to journal › Review article › peer-review
Open AccessFile3 Citations (Scopus)38 Downloads (Pure)
Datasets
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Data for "Blinded Predictions and Post-hoc Analysis of the Second Solubility Challenge Data: Exploring Training Data and Feature Set Selection for Machine and Deep Learning Models"
Conn, J. G. M. (Creator), Carter, J. W. (Creator), Conn, J. J. A. (Creator), Subramanian, V. (Creator), Baxter, A. (Creator), Engkvist, O. (Creator), Llinas, A. (Creator), Ratkova, E. L. (Creator), Pickett, S. D. (Creator), McDonagh, J. L. (Creator) & Palmer, D. S. (Creator), Zenodo, 11 May 2023
Dataset
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Data Underpinning: Toward physics-based solubility computation for pharmaceuticals to rival informatics
Fowles, D. J. (Creator), Palmer, D. S. (Creator), Guo, R. (Creator), Price, S. L. (Creator) & Mitchell, J. B. O. (Creator), University of St Andrews, 27 Apr 2023
DOI: 10.17630/4a3b4fba-1e62-46d5-af7a-6eedfb517c67
Dataset
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Supplementary data for "Discovery of the first potent and selective αvβ5 integrin inhibitor based on an amide-containing core"
Murphy, J. (Creator), Lippa, R. (Creator), Barrett, J. W. (Creator), Pal, S. (Creator), Rowedder, J. E. (Creator) & Barrett, T. N. (Creator), University of Strathclyde, 18 Feb 2020
DOI: 10.15129/a3237b0f-5b61-4da0-b78b-526726c136d1
Dataset
Activities
- 2 Invited talk
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AI for Drug Discovery
Palmer, D. (Speaker)
8 Nov 2022 → 10 Nov 2022Activity: Talk or Presentation › Invited talk
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Machine learning from continuous functions: applications to solvation thermodynamics and cancer diagnostics
Palmer, D. (Speaker)
5 Sept 2022Activity: Talk or Presentation › Invited talk