Accelerated Discovery and Development of New Medicines: Prosperity Partnership for a Healthier Nation

Project: Research

Project Details

Description

EP/S035990/1 £5,495, 023 from EPSRC.Prof William J. Kerr is the Strathclyde PI.

Next generation catalysis and synthesis: Chemists seeking to discover new medicines need new reactions that will allow them to make and investigate structures that are currently difficult, or even impossible, to make. A key objective of this proposal will be to develop new reagents, catalysts, and reactions to facilitate the more efficient preparation of drug-like molecules to accelerate drug discovery. Similarly, we will develop new ways of performing some of the most common chemical transformations in the synthesis of medicines whilst avoiding the use of carcinogenic reagents

Layman's description

We make the discoveries that will lead to better medicines, sooner and more efficiently than has been possible to date
Short titleProsperity Partnership
AcronymPP
StatusActive
Effective start/end date1/01/1931/12/23

Research Output

Alkene syn- and anti-oxyamination with malonoyl peroxides

Curle, J. M., Perieteanu, M. C., Humphreys, P. G., Kennedy, A. R. & Tomkinson, N. C. O., 21 Feb 2020, In : Organic Letters. 22, 4, p. 1659-1664 6 p.

Research output: Contribution to journalArticle

Open Access
File
  • 4 Downloads (Pure)

    A scalable, metal-, azide- and halogen-free method for the preparation of triazoles

    Clark, P. R., Williams, G. D., Hayes, J. F. & Tomkinson, N. C. O., 20 Apr 2020, In : Angewandte Chemie International Edition. 59, 17, p. 6740-6744 5 p.

    Research output: Contribution to journalArticle

  • Exploring ligand stability in protein crystal structures using binding pose metadynamics

    Fusani, L., Palmer, D. S., Somers, D. O. & Wall, I. D., 23 Mar 2020, In : Journal of Chemical Information and Modeling . 60, 3, p. 1528-1539 12 p.

    Research output: Contribution to journalArticle

    Open Access
    File
  • 2 Downloads (Pure)