20122024
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Research Output 2012 2019

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Article
2019
6 Downloads (Pure)

Metabolic dysregulation in vitamin E and carnitine shuttle energy mechanisms associate with human frailty

Rattray, N. J. W., Trivedi, D. K., Xu, Y., Chandola, T., Johnson, C. H., Marshall, A. D., Mekli, K., Rattray, Z., Tampubolon, G., Vanhoutte, B., White, I. R., Wu, F. C. W., Pendleton, N., Nazroo, J. & Goodacre, R., 5 Nov 2019, In : Nature Communications. 10, 1, 12 p., 5027.

Research output: Contribution to journalArticle

Open Access
File
carnitine
Carnitine
health
phenotype
Economics
2018
3 Citations (Scopus)
12 Downloads (Pure)

Re-engineering and evaluation of anti-DNA autoantibody 3E10 for therapeutic applications

Rattray, Z., Dubljevic, V., Rattray, N., Greenwood, D. L., Johnson, C. H., Campbell, J. A. & Hansen, J. E., 12 Feb 2018, In : Biochemical and Biophysical Research Communications. 496, 3, p. 858-864 7 p.

Research output: Contribution to journalArticle

Open Access
File
Autoantibodies
DNA Repair
DNA
Neoplasms
Repair
2017
7 Citations (Scopus)
35 Downloads (Pure)

Evaluation of aggregate and silicone-oil counts in pre-filled siliconized syringes: An orthogonal study characterising the entire subvisible size range.

Shah, M., Rattray, Z., Day, K., Uddin, S., Curtis, R., van der walle, C. F. & Pluen, A., 9 Jan 2017, In : International Journal of Pharmaceutics. 519, 1-2, p. 58-66 9 p.

Research output: Contribution to journalArticle

Open Access
File
Silicone Oils
Syringes
Polysorbates
Monoclonal Antibodies
Spectrum Analysis
10 Downloads (Pure)

Metabolomics guided pathway analysis reveals link between cancer metastasis, cholesterol sulfate, and phospholipids

Johnson, C. H., Santidrian, A. F., LeBoeuf, S. E., Kurzy, M. E., Rattray, N., Rattray, Z., Warth, B., Ritland, M., Hoang, L. T., Loriot, C., Higa, J., Hansen, J. E., Felding, B. H. & Siuzdak, G., 31 Oct 2017, In : Cancer and Metabolism. 5, 1

Research output: Contribution to journalArticle

Open Access
File
Metabolomics
Phospholipids
Neoplasm Metastasis
Neoplasms
Adipose Tissue
2015
11 Citations (Scopus)

Characterisation of stress‐induced aggregate size distributions and morphological changes of a bi‐specific antibody using orthogonal techniques

Hamrang, Z., Hussain, M., Tingey, K., Tracka, M., Casas-Finet, J. R., Uddin, S., van der walle, C. F. & Pluen, A., 14 Jul 2015, In : Journal of Pharmaceutical Sciences. 104, 8, p. 2473-2481 8 p.

Research output: Contribution to journalArticle

Bispecific Antibodies
Particle Size
Spectrum Analysis
Hot Temperature
Monoclonal Antibodies
2014
4 Citations (Scopus)

Monitoring the kinetics of CellTrace™ calcein red-orange AM intracellular accumulation with spatial intensity distribution analysis

Hamrang, Z., McGlynn, H. J., Clarke, D., Penny, J. & Pluen, A., Sep 2014, In : BBA - General Subjects. 1840, 9, p. 2914-2923 9 p.

Research output: Contribution to journalArticle

Fluorescence
Fluorescence Spectrometry
Kinetics
Fluorophores
Monitoring
3 Citations (Scopus)

On the cellular uptake and membrane effect of the multifunctional peptide, TatLK15

Alkotaji, M., Pluen, A., Zindy, E., Hamrang, Z. & Aojula, H., 1 Jan 2014, In : Journal of Pharmaceutical Sciences. 103, 1, p. 293-304 12 p.

Research output: Contribution to journalArticle

Peptides
Membranes
Small Interfering RNA
Cell-Penetrating Peptides
Oncogene Proteins
3 Citations (Scopus)

Quantitative assessment of P-glycoprotein expression and function using confocal image analysis

Hamrang, Z., Arthanari, Y., Clarke, D. & Pluen, A., 27 Aug 2014, In : Microscopy and Microanalysis. 20, 5, p. 1329-1339 10 p.

Research output: Contribution to journalArticle

Glycoproteins
P-Glycoprotein
image analysis
Image analysis
Fluorescent Antibody Technique
4 Citations (Scopus)

Real-time evaluation of aggregation using confocal imaging and image analysis tools

Hamrang, Z., Zindy, E., Clarke, D. & Pluen, A., 7 Feb 2014, In : Analyst. 139, 3, p. 564-568 4 p.

Research output: Contribution to journalArticle

raster
image analysis
Image analysis
Spectrum Analysis
Agglomeration
2012
9 Citations (Scopus)

Raster image correlation spectroscopy as a novel tool for the quantitative assessment of protein diffusional behaviour in solution

Hamrang, Z., Pluen, A., Zindy, E. & Clarke, D., 30 Jun 2012, In : Journal of Pharmaceutical Sciences. 101, 6, p. 2082-2093 12 p.

Research output: Contribution to journalArticle

Spectrum Analysis
Osmolar Concentration
Proteins
Fluorescence Spectrometry
Bovine Serum Albumin