20122024

Research output per year

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Personal profile

Personal Statement

Chancellor's Research Fellow and Lecturer in Translational Pharmaceutics

My field of expertise lies in the characterization of biologics and nanomedicine formulation attributes and in vivo performance using traditional and novel analytical approaches. 

Areas of research interest in my lab are summarized as follows;

  • Understanding environmental and physicochemical determinants of solution-phase formulation stability for antibody and suspension formulations.
  • Determining key critical quality attributes in particle design to inform optimal in vivo performance.
  • Evaluation of nanomedicine interaction with biological media, and the mechanism of cellular uptake in two- and three-dimensional cellular models.
  • Applying novel imaging modalities for evaluating drug and nanoparticle biodistribution, and impact on tumor response.
  • The interplay between the tumour microenvironment and nanomedicine in vivo performance with a view to developing biorelevant in vitro tests.

My lab is also interested in understanding the biological drivers of disease in lupus and oncology with a view to developing new diagnostics and therapeutics.

I am passionate about improving access to education, achievement and realizing potential for young budding scientists and am open to local STEM and healthcare-related widening participation initiatives. I am co-director (Pharmacy) with Dr Margaret Cunningham (Biomedical Sciences) for outreach in the Strathclyde Institute of Pharmacy & Biomedical Sciences.

Education/Academic qualification

Master of Pharmacy, University of Manchester

Sep 2004May 2008

Doctor of Philosophy

Sep 2009May 2013

Keywords

  • Drug Delivery
  • Drug development
  • Protein aggregation
  • Nanoparticles
  • Cancer therapy

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Projects

Research Output

Sex differences in colon cancer metabolism reveal a novel subphenotype

Cai, Y., Rattray, N. J. W., Zhang, Q., Mironova, V., Santos-Neto, A., Hsu, K-S., Rattray, Z., Cross, J. R., Zhang, Y., Paty, P. B., Khan, S. A. & Johnson, C. H., 17 Mar 2020, In : Scientific Reports. 10, 13 p., 4905.

Research output: Contribution to journalArticle

Open Access
File
  • Metabolic dysregulation in vitamin E and carnitine shuttle energy mechanisms associate with human frailty

    Rattray, N. J. W., Trivedi, D. K., Xu, Y., Chandola, T., Johnson, C. H., Marshall, A. D., Mekli, K., Rattray, Z., Tampubolon, G., Vanhoutte, B., White, I. R., Wu, F. C. W., Pendleton, N., Nazroo, J. & Goodacre, R., 5 Nov 2019, In : Nature Communications. 10, 1, 12 p., 5027.

    Research output: Contribution to journalArticle

    Open Access
    File
  • 1 Citation (Scopus)
    7 Downloads (Pure)

    Prizes

    AstraZeneca innovation award winner

    Zahra Rattray (Recipient), Aug 2008

    Prize: Prize (including medals and awards)

  • Award for best grade in physical pharmacy

    Zahra Rattray (Recipient), Sep 2005

    Prize: Prize (including medals and awards)

  • Activities

    CELL & GENE THERAPY:from concept to medicinal use

    Zahra Rattray (Organiser)
    14 May 2020

    Activity: Participating in or organising an event typesParticipation in conference

    Deadlier colon cancer develops differently in women and men

    Zahra Rattray (Recipient), Nicholas Rattray (Recipient)
    17 Mar 2020

    Activity: Other activity typesTypes of Public engagement and outreach - Media article or participation