• United Kingdom

Accepting PhD Students

1997 …2023
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Research Output 1997 2020

2020
Open Access
File
Microfluidics
Nanoparticles
Proteins
Particle Size
Emulsifying Agents
2019
2 Citations (Scopus)
Unilamellar Liposomes
Microfluidics
Liposomes
Propane
Macrophages
2 Citations (Scopus)
9 Downloads (Pure)
Open Access
File
Proteins
Liposomes
High Pressure Liquid Chromatography
Nucleic Acids
Light
1 Downloads (Pure)

Conceptualisation, development, fabrication and in vivo validation of a novel disintegration tester for orally disintegrating tablets

Koner, J. S., Rajabi-Siahboomi, A. R., Missaghi, S., Kirby, D., Perrie, Y., Ahmed, J. & Mohammed, A. R., 28 Aug 2019, In : Scientific Reports. 9, 1, 9 p., 12467.

Research output: Contribution to journalArticle

Open Access
File
Tablets
Mouth
Hockey
Pharmacopoeias
Dosage Forms
3 Citations (Scopus)
14 Downloads (Pure)

Exploitation of the bilosome platform technology to formulate antibiotics and enhance efficacy of melioidosis treatments

D'Elia, R. V., Woods, S., Butcher, W., McGahon, J., Khadke, S., Perrie, Y., Williamson, E. D. & Roberts, C. W., 28 Mar 2019, In : Journal of Controlled Release. 298, p. 202-212 11 p.

Research output: Contribution to journalArticle

Open Access
File
Melioidosis
Microbiota
Burkholderia pseudomallei
Anti-Bacterial Agents
Technology
4 Citations (Scopus)

Formulation and manufacturing of lymphatic targeting liposomes using microfluidics

Khadke, S., Roces, C. B., Cameron, A., Devitt, A. & Perrie, Y., 10 Aug 2019, In : Journal of Controlled Release. 307, p. 211-220 10 p.

Research output: Contribution to journalArticle

Microfluidics
Liposomes
Avidin
Biotin
Proteins

Freeze-drying cycle optimization for the rapid preservation of protein-loaded liposomal formulations

Hussain, M. T., Forbes, N., Perrie, Y., Malik, K. P., Duru, C. & Matejtschuk, P., 19 Sep 2019, (Accepted/In press) In : International Journal of Pharmaceutics.

Research output: Contribution to journalArticle

Freeze Drying
Liposomes
Ovalbumin
Fluid Therapy
Proteins
11 Downloads (Pure)

High-throughput screening of excipients with a biological effect: a kinetic study on the effects of surfactants on efflux-mediated transport

Pollard, J., Rajabi-Siahboomi, A., Badhan, R. K. S., Mohammed, A. R. & Perrie, Y., 1 Jun 2019, In : Journal of Pharmacy and Pharmacology. 71, 6, p. 889-897 9 p.

Research output: Contribution to journalArticle

Open Access
File
Poloxamer
Excipients
Surface-Active Agents
Polysorbates
Rhodamine 123
3 Citations (Scopus)

Intracellular uptake of EGCG-loaded deformable controlled release liposomes for skin cancer

Marwah, M., Perrie, Y., Badhan, R. K. S. & Lowry, D., 9 May 2019, In : Journal of Liposome Research.

Research output: Contribution to journalArticle

Polysorbates
Skin Neoplasms
Liposomes
Skin
Elasticity
2 Downloads (Pure)

Investigating prime-pull vaccination through a combination of parenteral vaccination and intranasal boosting

Roces, C. B., Hussain, M. T., Schmidt, S. T., Christensen, D. & Perrie, Y., 31 Dec 2019, In : Vaccines. 8, 1, 22 p., 10.

Research output: Contribution to journalArticle

Open Access
File
Vaccination
Antigens
Tuberculosis Vaccines
Lung
Subunit Vaccines

Liposomes: a promising carrier for respiratory syncytial virus therapeutics

Joshi, S., Bawage, S., Tiwari, P., Kirby, D., Perrie, Y., Dennis, V. & Singh, S. R., 7 Aug 2019, In : Expert Opinion on Drug Delivery. 16, 9, p. 969-980 12 p.

Research output: Contribution to journalReview article

Respiratory Syncytial Viruses
Liposomes
Human respiratory syncytial virus
Therapeutics
Respiratory Syncytial Virus Infections

Microfluidic manufacture of solid lipid nanoparticles: a case study on tristearin-based systems

Anderluzzi, G. & Perrie, Y., 20 Sep 2019, (Accepted/In press) In : Drug Delivery Letters. 25 p.

Research output: Contribution to journalArticle

Microfluidics
Nanoparticles
Lipids
Particle Size
Proteins
3 Citations (Scopus)
28 Downloads (Pure)

Nanomedicines for the delivery of biologics

Wahlich, J., Desai, A., Greco, F., Hill, K., Jones, A. T., Mrsny, R., Pasut, G., Perrie, Y., Seib, F. P., Seymour, L. W. & Uchegbu, I. F., 3 May 2019, In : Pharmaceutics. 11, 5, 14 p., 210.

Research output: Contribution to journalArticle

Open Access
File
Nanomedicine
Biological Products
Technology
Pharmaceutical Preparations
Focus Groups
15 Citations (Scopus)
Open Access
File
Microfluidics
Liposomes
Proteins
Sonication
Particle Size

Scalable manufacturing processes for solid lipid nanoparticles

Anderluzzi, G., Lou Ramirez, G., Su, Y. & Perrie, Y., 30 Nov 2019, In : Pharmaceutical Nanotechnology. 7, 6, p. 444-459 16 p.

Research output: Contribution to journalArticle

Nanoparticles
Lipids
Particle Size
Pressure
Microfluidics
2 Citations (Scopus)
3 Downloads (Pure)
Open Access
File
Trehalose
Microfluidics
Liposomes
Avidin
Biotin
2 Downloads (Pure)

The impact of solvent selection: strategies to guide the manufacturing of liposomes using microfluidics

Webb, C., Khadke, S., Schmidt, S. T., Roces, C. B., Forbes, N., Berrie, G. & Perrie, Y., 4 Dec 2019, In : Pharmaceutics. 11, 12, 15 p., 653.

Research output: Contribution to journalArticle

Open Access
File
Microfluidics
Liposomes
Methanol
Lipids
Particle Size
2018
2 Citations (Scopus)
21 Downloads (Pure)

Anti-RSV peptide-loaded liposomes for the inhibition of respiratory syncytial virus

Joshi, S., Chaudhari, A. A., Dennis, V., Kirby, D. J., Perrie, Y. & Singh, S. R., 9 May 2018, In : Bioengineering. 5, 2, 14 p., 37.

Research output: Contribution to journalArticle

Open Access
File
Respiratory Syncytial Viruses
Liposomes
Viruses
Peptides
Fusion reactions
3 Citations (Scopus)
1 Downloads (Pure)

High potency of lipid conjugated TLR7 agonist requires nanoparticulate or liposomal formulation

Gadd, A. J. R., Castelletto, V., Kabova, E., Shankland, K., Perrie, Y., Hamley, I., Cobb, A. J. A., Greco, F. & Edwards, A. D., 15 Oct 2018, In : European Journal of Pharmaceutical Sciences. 123, p. 268-276 9 p.

Research output: Contribution to journalArticle

Open Access
Toll-Like Receptor 7
Dimethyl Sulfoxide
Nanoparticles
Lipids
Liposomes
8 Citations (Scopus)
1 Downloads (Pure)

Lipid conjugation of TLR7 agonist Resiquimod ensures co-delivery with the liposomal Cationic Adjuvant Formulation 01 (CAF01) but does not enhance immunopotentiation compared to non-conjugated Resiquimod+CAF01

Wilkinson, A., Lattmann, E., Roces, C. B., Pedersen, G. K., Christensen, D. & Perrie, Y., 10 Dec 2018, In : Journal of Controlled Release. 291, p. 1-10 10 p.

Research output: Contribution to journalArticle

Open Access
File
resiquimod
Toll-Like Receptor 8
Toll-Like Receptor 7
Liposomes
Toll-Like Receptors
3 Citations (Scopus)
9 Downloads (Pure)

Metallosomes for biomedical applications by mixing molybdenum carbonyl metallosurfactants and phospholipids

Marín-García, M., Benseny-Cases, N., Camacho, M., Perrie, Y., Suades, J. & Barnadas-Rodríguez, R., 28 Jun 2018, In : Dalton Transactions. 11 p.

Research output: Contribution to journalArticle

Open Access
File
Molybdenum
Carbon Monoxide
Phospholipids
Liposomes
Organic solvents
5 Citations (Scopus)
38 Downloads (Pure)

Point of use production of liposomal solubilised products

Khadke, S., Stone, P., Rozhin, A. G., Kroonen, J. & Perrie, Y., 15 Feb 2018, In : International Journal of Pharmaceutics. 537, 1-2, p. 1-8 8 p.

Research output: Contribution to journalArticle

Open Access
File
Tablets
Pharmaceutical Preparations
Pediatrics
Ethiopia
Dosage Forms
2017
13 Downloads (Pure)

Activated carbon as a carrier for amorphous drug delivery: effect of drug characteristics and carrier wettability

Miriyala, N., Ouyang, D., Perrie, Y., Lowry, D. & Kirby, D. J., 6 Mar 2017, (Accepted/In press) In : European Journal of Pharmaceutics and Biopharmaceutics. 28 p.

Research output: Contribution to journalArticle

Open Access
File
Wettability
Drug Carriers
Carbon
Pharmaceutical Preparations
Caco-2 Cells
10 Downloads (Pure)

Application of pharmacokinetics modelling to predict human exposure of a cationic liposomal subunit antigen vaccine system

Badhan, R. K. S., Khadke, S. & Perrie, Y., 7 Dec 2017, In : Pharmaceutics. 9, 4, 15 p.

Research output: Contribution to journalArticle

Open Access
File
Subunit Vaccines
Pharmacokinetics
Antigens
Muscles
Trehalose
8 Citations (Scopus)
32 Downloads (Pure)

Development of a solid dosage platform for the oral delivery of bilayer vesicles

Wilkhu, J. S., McNeil, S. E., Anderson, D. E., Kirchmeier, M. & Perrie, Y., 15 Oct 2017, In : European Journal of Pharmaceutical Sciences. 108, p. 71-77 7 p.

Research output: Contribution to journalArticle

Open Access
File
Tablets
Mannitol
Dextrans
Antigens
Vaccines
18 Citations (Scopus)
163 Downloads (Pure)

Formation and purification of tailored liposomes for drug delivery using a module-based micro continuous-flow system

Dimov, N., Kastner, E., Hussain, M. T., Perrie, Y. & Szita, N., 1 Dec 2017, In : Scientific Reports. 7, 1, 19 p., 12045.

Research output: Contribution to journalArticle

Open Access
File
Nanomedicine
Liposomes
Pharmaceutical Preparations
Lipids
Ovalbumin
2 Citations (Scopus)
16 Downloads (Pure)

Nanomedicines: exploring the past, present and future

Perrie, Y. & Ramsay, E., 1 Dec 2017, In : Drug Discovery World. 18, Fall, p. 17-22 6 p.

Research output: Contribution to journalArticle

Open Access
File
Nanomedicine
Nanoparticles
Microfluidics
Drug Industry
Liposomes
1 Citation (Scopus)
16 Downloads (Pure)

Novel nano-biomaterials for inhibition of respiratory syncytial virus

Joshi, S., Kirby, D., Perrie, Y. & Singh, S. R., 14 May 2017, Biotech, Biomaterials and Biomedical: TechConnect Briefs 2017. California, p. 75-78 4 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution book

Open Access
File
Respiratory Syncytial Viruses
Liposomes
Biocompatible Materials
Viruses
Biomaterials
17 Citations (Scopus)
70 Downloads (Pure)

TBVAC2020: advancing tuberculosis vaccines from discovery to clinical development

Kaufmann, S. H. E., Dockrell, H. M., Drager, N., Ho, M. M., McShane, H., Neyrolles, O., Ottenhoff, T. H. M., Patel, B., Roordink, D., Spertini, F., Stenger, S., Thole, J., Verreck, F. A. W., Williams, A., Britton, W., Triccas, J., Counoupas, C., Grooten, J., Marie-Ange Demoitie, D., Romano, M. & 31 others, Huygen, K., Tima, H. G., Mascart, F., Andersen, P., Aagaard, C., Christensen, D., Ruhwald, M., Lindenstrom, T., Charneau, P., Guilhot, C., Peixoto, A., Gilleron, M., Vergne, I., Locht, C., Brosch, R., Inchauspe, G., Theung Long, S. L., Weiner, J., Maertzdorf, J., Nieuwenhuizen, N., Bastian, M., Kallert, S., Gordon, S., Caccamo, N., Goletti, D., Nisini, R., Shin, S. J., Cho, S. N., Lee, H., Perrie, Y. & TBVAC2020 Consortium, 4 Oct 2017, In : Frontiers in Immunology. 8, OCT, p. 1-18 18 p., 1203.

Research output: Contribution to journalReview article

Open Access
File
Tuberculosis Vaccines
Vaccines
Information Dissemination
Research
Patient Selection
2016
38 Citations (Scopus)
37 Downloads (Pure)

Characterization of microvesicles released from human red blood cells

Nguyen, D. B., Thuy Ly, T. B., Wesseling, M. C., Hittinger, M., Torge, A., Devitt, A., Perrie, Y. & Bernhardt, I., 4 Mar 2016, In : Cellular Physiology and Biochemistry. 38, 3, p. 1085-1099 15 p.

Research output: Contribution to journalArticle

Open Access
File
Erythrocytes
Atomic Force Microscopy
Electron Scanning Microscopy
Protein Kinase C
Cell-Derived Microparticles
33 Citations (Scopus)
87 Downloads (Pure)

Designing liposomal adjuvants for the next generation of vaccines

Perrie, Y., Crofts, F., Devitt, A., Griffiths, H. R., Kastner, E. & Nadella, V., 1 Apr 2016, In : Advanced Drug Delivery Reviews. 99, Pt A, p. 85-96 12 p.

Research output: Contribution to journalArticle

Open Access
File
Liposomes
Vaccines
DNA Vaccines
Immune System
Lymph Nodes
2 Citations (Scopus)

Environmental scanning electron microscope imaging of vesicle systems

Perrie, Y., Ali, H., Kirby, D. J., Mohammed, A. U. R., McNeil, S. E. & Vangala, A., 12 Nov 2016, Methods in Molecular Biology. D'Souza, G. G. M. (ed.). New York, p. 131-143 13 p. (Methods in Molecular Biology; vol. 1522).

Research output: Chapter in Book/Report/Conference proceedingChapter

Liposomes
Electrons
Electron Scanning Microscopy
Freeze Fracturing
Transmission Electron Microscopy
4 Citations (Scopus)
17 Downloads (Pure)

Human rhinovirus-induced inflammatory responses are inhibited by phosphatidylserine containing liposomes

Stokes, CA., Kaur, R., Edwards, MR., Mondhe, M., Robinson, D., Prestwich, EC., Hume, RD., Marshall, CA., Perrie, Y., O'Donnell, VB., Harwood, JL., Sabroe, I. & Parker, LC., 24 Feb 2016, In : Mucosal Immunology. 14 p.

Research output: Contribution to journalArticle

Open Access
File
Rhinovirus
Phosphatidylserines
Liposomes
Membrane Microdomains
Epithelial Cells

Manufacturing methods for liposome adjuvants

Perrie, Y., Kastner, E., Khadke, S., Roces, C. B. & Stone, P., 8 Oct 2016, Vaccine Adjuvants: Methods and Protocols. Fox, C. B. (ed.). New York, p. 127-144 18 p. (Methods in Molecular Biology; vol. 1494).

Research output: Chapter in Book/Report/Conference proceedingChapter

Liposomes
Antigens
Costs and Cost Analysis
Lipid Bilayers
Vaccines
31 Citations (Scopus)
289 Downloads (Pure)

Microfluidics based manufacture of liposomes simultaneously entrapping hydrophilic and lipophilic drugs

Joshi, S., Hussain, M. T., Roces, C. B., Anderluzzi, G., Kastner, E., Salmaso, S., Kirby, D. J. & Perrie, Y., 30 Nov 2016, In : International Journal of Pharmaceutics. 514, 1, p. 160–168 9 p.

Research output: Contribution to journalArticle

Open Access
File
Microfluidics
Liposomes
Pharmaceutical Preparations
Glipizide
Metformin

Principles of controlled release

Perrie, Y., Rades, T. & Graeser, K., 17 Aug 2016, Drug Delivery: Fundamentals and Applications. Hillery, A. M. & Park, K. (eds.). Boca Raton, FL, p. 25-46 22 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Pharmaceutical Preparations
Dosage Forms
Drug Delivery Systems
Drug-Related Side Effects and Adverse Reactions
Pharmacokinetics
10 Citations (Scopus)
56 Downloads (Pure)

Rapid quantification and validation of lipid concentrations within liposomes

Roces, C. B., Kastner, E., Stone, P., Lowry, D. & Perrie, Y., 13 Sep 2016, In : Pharmaceutics. 8, 29, p. 1-11 11 p.

Research output: Contribution to journalArticle

Open Access
File
Liposomes
Lipids
Trehalose
Phosphorylcholine
Cholesterol
22 Citations (Scopus)
32 Downloads (Pure)

The administration route is decisive for the ability of the vaccine adjuvant CAF09 to induce antigen-specific CD8+ T-cell responses: the immunological consequences of the biodistribution profile

Schmidt, S. T., Khadke, S., Korsholm, K. S., Perrie, Y., Rades, T., Andersen, P., Foged, C. & Christensen, D., 10 Oct 2016, In : Journal of Controlled Release. 239, p. 107-117 11 p.

Research output: Contribution to journalArticle

Open Access
File
CD8 Antigens
Ovalbumin
Vaccines
T-Lymphocytes
Immunization
2015
8 Citations (Scopus)
26 Downloads (Pure)

A holistic multi evidence approach to study the fragmentation behaviour of crystalline Mannitol

Koner, J. S., Rajabi-Siahboomi, A., Bowen, J., Perrie, Y., Kirby, D. & Mohammed, A. R., 10 Nov 2015, In : Scientific Reports. 5, p. 16352

Research output: Contribution to journalArticle

Open Access
File
Mannitol
Tablets
Crystalline materials
Powders
Ball milling
12 Citations (Scopus)
141 Downloads (Pure)

A pragmatic approach for engineering porous mannitol and mechanistic evaluation of particle performance

Al-Khattawi, A., Koner, J., Rue, P., Kirby, D., Perrie, Y., Rajabi-Siahboomi, A. & Mohammed, A. R., 1 Aug 2015, In : European Journal of Pharmaceutics and Biopharmaceutics. 94, p. 1-10 10 p.

Research output: Contribution to journalArticle

Open Access
File
Mannitol
Tablets
Porosity
Hardness
Temperature
6 Citations (Scopus)
35 Downloads (Pure)

Correlating liposomal adjuvant characteristics to in-vivo cell-mediated immunity using a novel Mycobacterium tuberculosis fusion protein: a multivariate analysis study

Kastner, E., Hussain, M. J., Bramwell, V. W., Christensen, D. & Perrie, Y., 1 Mar 2015, In : Journal of Pharmacy and Pharmacology. 67, 3, p. 450-463 14 p.

Research output: Contribution to journalArticle

Open Access
File
Trehalose
Mycobacterium tuberculosis
Cellular Immunity
Interleukin-2
Interleukin-6
50 Downloads (Pure)

Enhancing vaccine design strategies: applications for protein science, proteomics and adjuvants

Perrie, Y., Griffiths, H. R. & Jones, D., 26 Mar 2015, In : Journal of Pharmacy and Pharmacology. 67, 3, p. 287-289 3 p.

Research output: Contribution to journalEditorial

Open Access
File
Proteomics
Vaccines
Vaccination
Developed Countries
Communicable Diseases
54 Citations (Scopus)
98 Downloads (Pure)

Microfluidic-controlled manufacture of liposomes for the solubilisation of a poorly water soluble drug

Kastner, E., Verma, V., Lowry, D. & Perrie, Y., 15 May 2015, In : International Journal of Pharmaceutics. 485, 1-2, p. 122-130 9 p.

Research output: Contribution to journalArticle

Open Access
File
Microfluidics
Liposomes
Water
Pharmaceutical Preparations
Propofol

Nothing wrong with the quality of MPharm graduates

Perrie, Y. & Marshall, K., 3 Aug 2015, In : Pharmaceutical Journal. 295, 7876-7877, p. 147 1 p.

Research output: Contribution to journalLetter

Pharmacy Schools
Pharmacists
Pharmaceutical Preparations
75 Downloads (Pure)

Paediatric drug development of ramipril reformulation, in vitro and in vivo evaluation

Russell, C., Begum, S., Hussain, Y., Hussain, M., Huen, D., Rahman, A. S., Perrie, Y. & Mohammed, A. R., 7 May 2015, In : Journal of Drug Targeting. 23, 9, p. 854-863 10 p.

Research output: Contribution to journalArticle

Open Access
File
Ramipril
Pediatrics
Cyclodextrins
Pharmaceutical Preparations
Suspensions
2014
5 Citations (Scopus)
29 Downloads (Pure)

Consideration of the efficacy of non-ionic vesicles in the targeted delivery of oral vaccines

Wilkhu, J. S., McNeil, S. E., Anderson, D. E. & Perrie, Y., 30 Jun 2014, In : Drug Delivery and Translational Research. 4, 3, p. 233-45 13 p.

Research output: Contribution to journalArticle

Open Access
File
Vaccines
Antigens
Peyer's Patches
Surface-Active Agents
Liposomes
24 Citations (Scopus)
46 Downloads (Pure)

Effect of incorporating cholesterol into DDA:TDB liposomal adjuvants on bilayer properties, biodistribution, and immune responses

Kaur, R., Henriksen-Lacey, M., Wilkhu, J., Devitt, A., Christensen, D. & Perrie, Y., 6 Jan 2014, In : Molecular Pharmaceutics. 11, 1, p. 197-207 11 p.

Research output: Contribution to journalArticle

Open Access
File
Liposomes
Cholesterol
Membrane Fluidity
Immunoglobulin G
Artificial Membranes
61 Citations (Scopus)
73 Downloads (Pure)

High-throughput manufacturing of size-tuned liposomes by a new microfluidics method using enhanced statistical tools for characterization

Kastner, E., Kaur, R., Lowry, D., Moghaddam, B., Wilkinson, A. & Perrie, Y., 30 Dec 2014, In : International Journal of Pharmaceutics. 477, 1-2, p. 361-368 8 p.

Research output: Contribution to journalArticle

Open Access
File
Microfluidics
Liposomes
Transfection
Multivariate Analysis
16 Citations (Scopus)
40 Downloads (Pure)

Investigating the role of cholesterol in the formation of non-ionic surfactant based bilayer vesicles: thermal analysis and molecular dynamics

Wilkhu, J. S., Ouyang, D., Kirchmeier, M. J., Anderson, D. E. & Perrie, Y., 30 Jan 2014, In : International Journal of Pharmaceutics. 461, 1-2, p. 331-41 11 p.

Research output: Contribution to journalArticle

Open Access
File
Molecular Dynamics Simulation
Surface-Active Agents
Glycerol
Liposomes
Hot Temperature
17 Citations (Scopus)
119 Downloads (Pure)

Th1 immune responses can be modulated by varying dimethyldioctadecylammonium and distearoyl-sn-glycero-3-phosphocholine content in liposomal adjuvants

Hussain, M. J., Wilkinson, A., Bramwell, V. W., Christensen, D. & Perrie, Y., 31 Mar 2014, In : Journal of Pharmacy and Pharmacology. 66, 3, p. 358-366 9 p.

Research output: Contribution to journalArticle

Open Access
File
Phosphorylcholine
dimethyldioctadecylammonium
Tuberculosis Vaccines
Antigens
Th1 Cells