Projects per year
Personal profile
Personal Statement
I joined the Department of Immunology at Strathclyde University as a lecturer in 1991 and was appointed Professor of Molecular Immunology in 2002. Immunology was one of five University departments, which merged to form Strathclyde Institute of Pharmacy and Biomedical Sciences (SIPBS) in 2006. I acted as Director of Research in SIPBS from August 2009 until the end of 2013 and was previously Head of The immunology Department during the academic year, 2005-6.
My research interests lie in elucidating the molecular mechanisms by which parasitic worms modulate the host immune system. A particular focus is on ES-62, an anti-inflammatory molecule secreted by the filarial nematode Acanthocheilonema viteae, which we are currently exploiting with a view to developing novel drugs for allergic and autoimmune diseases. This interest in immunology and parasitology also extends to my areas of teaching.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Collaborations and top research areas from the last five years
Projects
- 13 Finished
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How does the immunomodulatory parasitic worm product ES-62 rewire bone marrow cells to increase healthspan and lifespan in obesity-accelerated ageing?
Harnett, W. (Principal Investigator) & Hoskisson, P. (Co-investigator)
MRC (Medical Research Council)
1/06/21 → 31/12/24
Project: Research
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Does the parasitic worm product ES-62 resolve aberrant chronic inflammation by sensing and normalising the gut microbiome and intestinal integrity?
Harnett, W. (Principal Investigator) & Hoskisson, P. (Co-investigator)
BBSRC (Biotech & Biological Sciences Research Council)
10/05/21 → 31/10/24
Project: Research
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Reduction in creatine metabolites in macrophages exposed to small molecule analogues of the anti-inflammatory parasitic worm product ES-62
Alanazi, S., Doonan, J., Lumb, F. E., Alenzi, N., Jabbar, S., Al-Riyami, L., Suckling, C. J., Harnett, W. & Watson, D. G., 19 Feb 2024, In: Parasite Immunology. 46, 2, 6 p., e13026.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)29 Downloads (Pure) -
Epigenetic changes induced by parasitic worms and their excretory-secretory products
Harnett, W. & Harnett, M. M., 9 Feb 2024, In: Biochemical Society Transactions. 52, 1, p. 55–63Research output: Contribution to journal › Review article › peer-review
Open AccessFile2 Citations (Scopus)13 Downloads (Pure)
Prizes
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Associate Professorship at the Faculty of Medicine, Paris Descartes
Harnett, W. (Recipient), 1 Oct 2007
Prize: Appointment
Activities
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Molecular and Cellular Biology of Helminth Parasites IX
Harnett, W. (Chair)
30 Aug 2015 → 4 Sept 2015Activity: Participating in or organising an event types › Participation in conference
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The parasitic worm product ES-62: a starting point for novel anti-inflammatory drug development
Harnett, W. (Invited speaker)
25 Aug 2015Activity: Talk or presentation types › Invited talk
Equipment
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EVOS FL Auto, Imaging Kit
Strathclyde Institute Of Pharmacy And Biomedical SciencesFacility/equipment: Equipment