20022020

Research output per year

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Personal profile

Personal Statement

I joined the Department of Immunology at Strathclyde University as a lecturer in 1991 and was appointed Professor of Molecular Immunology in 2002. Immunology was one of five University departments, which merged to form Strathclyde Institute of Pharmacy and Biomedical Sciences (SIPBS) in 2006. I acted as Director of Research in SIPBS from August 2009 until the end of 2013 and was previously Head of The immunology Department during the academic year, 2005-6.

My research interests lie in elucidating the molecular mechanisms by which parasitic worms modulate the host immune system. A particular focus is on ES-62, an anti-inflammatory molecule secreted by the filarial nematode Acanthocheilonema viteae, which we are currently exploiting with a view to developing novel drugs for allergic and autoimmune diseases. This interest in immunology and parasitology also extends to my areas of teaching.

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Projects

Research Output

The parasitic worm product ES-62 promotes health- and life-span in a high calorie diet accelerated mouse model of ageing

Crowe, J., Lumb, F. E., Doonan, J., Broussard, M., Tarafdar, A., Pineda, M. A., Landabaso, C., Mulvey, L., Hoskisson, P. A., Babayan, S. A., Selman, C., Harnett, W. & Harnett, M. M., 12 Mar 2020, In : PLOS Pathogens. 16, 3, 33 p., e1008391.

Research output: Contribution to journalArticle

Open Access
File
  • 6 Downloads (Pure)

    Site-specific glycoproteomic characterization of ES-62: the major secreted product of the parasitic worm Acanthocheilonema viteae

    North, S. J., Botchway, K., Doonan, J., Lumb, F. E., Dell, A., Harnett, W. & Haslam, S. M., 30 Aug 2019, In : Glycobiology. 29, 8, p. 562-571 10 p.

    Research output: Contribution to journalArticle

    Open Access
    File
  • 1 Downloads (Pure)

    Thesis

    The effects of small molecule analogues of the anti-inflammatory parasitic worm product ES-62 on the metabolome of mouse bone marrow-derived macrophages

    Author: Alanazi, S. T. K., 21 Jun 2018

    Supervisor: Harnett, W. (Supervisor) & Watson, D. (Supervisor)

    Student thesis: Doctoral Thesis

    Prizes

  • Activities

    • 20 Participation in conference
    • 20 Key-note speaker and plenary lectures at conferences
    • 7 Invited talk
    • 5 Editorial board member

    Molecular and Cellular Biology of Helminth Parasites IX

    William Harnett (Speaker)
    30 Aug 20154 Sep 2015

    Activity: Participating in or organising an event typesParticipation in conference

    Molecular and Cellular Biology of Helminth Parasites IX

    William Harnett (Chair)
    30 Aug 20154 Sep 2015

    Activity: Participating in or organising an event typesParticipation in conference