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Personal profile

Personal Statement

 

ORCID: 0000-0001-6169-5035

 

CURRENT POSITIONS

** University Lecturer & Chancellor's Research Fellow in Medicinal Chemistry

Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, United Kingdom

 

**Adjunct Professor & Principal Investigator

Drug Discovery Programme, Faculty of Pharmacy, University of Helsinki, Finland

 

EDUCATION AND DEGREES AWARDED

**Title of “Docent” (Adjunct Professor) in Pharmaceutical Chemistry, University of Helsinki, Finland, 2015

**Ph.D. in Pharmaceutical Organic Chemistry, University of Coimbra, Portugal & University of Maryland, USA, (highest-scoring grade, “Passed with Distinction and Honours”), 2008

**Degree in Pharmaceutical Sciences (Pharm.D.), University of Coimbra, Portugal, Grade 17 out of 20 (First-class honours), awarded with the “ Sociedade Farmacêutica Lusitana Award” (best student of Pharmaceutical Sciences of the year in Portugal), 2003

 

RESEARCH AREAS

Drug Discovery, Medicinal Chemistry, Natural Products, Antimicrobial and anti-biofilm agents & materials, Neglected diseases, Cancer, (Neuro)inflammation

 

MAJOR FUNDING SOURCES

The Finnish Funding Agency for Innovation (TEKES); Huonekalusäätio; University of Helsinki Research Funds; Magnus Ehrnrooth Foundation; Portuguese Science and Technology Foundation (FCT); FP7-HEALTH-2013-INNOVATION-1 (European Funding); Academy of Finland

 

CURRENT COMPOSITION OF RESEARCH GROUP

Doctoral students

Declan Mullen (Oct 2018 - )

Ghada Hassan (Sep 2016-); Sustainable antimicrobial coatings

Laura Kolsi (May 2014-); New diterpenoids with anti-inflammatory and antitumoral activity

Tiina Ahonen (Sep 2014-); New drugs for chronic pain

Nina Forsman (co-supervisor; Sep 2016-); Sustainable multifunctional coatings for textiles and other cellulosic materials

M.Sc. students

Ruaraidh MacGregor (May - Aug 2018), Cellulose antimicrobial solutions

Graeme Lester (May - Aug 2018), The anticancer activity of picealactones

 

FORMER RESEARCH GROUP MEMBERS

Post-doctoral researchers

Xing Wan (May 2017- Jan 2018); Sustainable antimicrobial coatings

Dr. Leena Keurulainen (Sep 2016 - Apr 2017); Sustainable antimicrobial coatings

Doctoral students

Dr. Raisa Haavikko (co-supervisor; graduated 2015); Synthesis of betulins with new bioactivities

Dr. Nehad El-Salamouni (visiting doctoral student; graduated 2013); Design and synthesis of some novel phenolic compounds and their quinone oxidation products of potential biological activities

 

M.Sc. students

M.Sc. Declan Mullen (main supervisor, graduated 2018); Targeting metabolic serine hydrolases for the development of new anti-inflammatory drug leads

M.Sc. Henni-Karoliina Ropponen (main supervisor, graduated 2018); Exploiting the Potential of Abietane-type Diterpenoids for the Design and Synthesis of Antimicrobial and Anti-biofilm Agents

M.Sc. Peter Grutschreiber (co-supervisor, graduated 2017); Synthesis and characterisation of morphine derivatives as intermediates in development of new compounds for treatment of chronic pain

M.Sc. Tiina Mäenpää (co-supervisor, graduated 2017); Derivatives of abietic acid and their bioactivity

M.Sc. Eunice Cavalheiro (co-supervisor, graduated 2017); Synthesis of 5-methylene(thio)ureas (thio)barbiturates as potential xanthine oxidase inhibitors

M.Sc. Sara Krogerus (co-supervisor, graduated 2016); Benzylic oxidations of dehydroabietic acid derivatives at positions 7 and 15

M.Sc. Ghada Hassan (main supervisor, graduated 2016); Synthesis of abietic and dehydroabietic acid derivatives to target bacterial biofilms

M.Sc. Augustin Long (co-supervisor, graduated 2014); Modification of resin acids for the production of biologically active molecules

M.Sc. Anna-Kaarina Palomäki (co-supervisor; graduated 2013); Lääkeaineisiin ja rohdoksiin liittyvien tutkimuksellisten kokeellisten töiden kehittäminen lukion kemianopetukseen

 

Education/Academic qualification

University of Helsinki

Doctor of Philosophy, University of Coimbra

External positions

Management Committee Member (CM1307)

Jan 2016Mar 2018

Adjunct Professor & Principal Investigator, University of Helsinki

Jun 2015 → …

Fingerprint Fingerprint is based on mining the text of the person's scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

Abietane Diterpenes Medicine & Life Sciences
Derivatives Chemical Compounds
Prostatic Neoplasms Medicine & Life Sciences
Steroid 17-alpha-Hydroxylase Medicine & Life Sciences
Androgen Receptors Medicine & Life Sciences
Indazoles Chemical Compounds
Steroids Chemical Compounds
Diterpenes Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 2011 2021

DTP 2018-19 University of Strathclyde | Mullen, Declan

Moreira, V., Parkinson, J. & Mullen, D.

EPSRC (Engineering and Physical Sciences Research Council)

1/10/181/10/21

Project: Research Studentship - Internally AllocatedResearch Studentship (Internally Allocated)

RESICELL: Sustainable Hydrophobic Materials for Antimicrobial Coatings

Moreira, V.

1/09/1631/01/18

Project: Projects from Previous EmploymentKnowledge Exchange

Research Output 2005 2018

Catalytic, tunable, one-step bismuth(III) triflate reaction with alcohols: dehydration vs dimerization

Kolsi, L. E., Yli-Kauhaluoma, J. & Moreira, V. M., 9 Aug 2018, In : ACS Omega. 3, 8, p. 8836–8842 7 p.

Research output: Contribution to journalArticle

Open Access
File
Bismuth
Dimerization
Dehydration
Alcohols
Color

Dehydroabietic oximes halt pancreatic cancer cell growth in the G1 phase through induction of p27 and downregulation of cyclin D1

Kolsi, L. E., Leal, A. S., Yli-Kauhaluoma, J., Liby, K. T. & Moreira, V. M., 12 Oct 2018, (Accepted/In press) In : Scientific Reports.

Research output: Contribution to journalArticle

Oximes
Cyclin D1
G1 Phase
Pancreatic Neoplasms
Down-Regulation

Prizes

Doctoral scholarship (SFRH/BD/12508/2003)

Vania Moreira (Recipient), 2003

Prize: Fellowship awarded competitively

Post-doctoral fellowship (SFRH/BPD/45037/2008)

Vania Moreira (Recipient), 2009

Prize: Fellowship awarded competitively

Boron
Antineoplastic Agents

Activities 2006 2018

Bio-based hybrid antimicrobial surfaces

Moreira, V. (Speaker)
4 Jul 2018

Activity: Talk or presentationInvited talk