Projects per year
I obtained my BSc (Hons) in Pharmacology from the University of Glasgow (1992) and my PhD in Neuroscience from the University of Bristol (1996) before undertaking postdoctoral research at the University of Chicago and Imperial College London. I took up my position here at Strathclyde in 2002.
My research interest lies primarily in the field of neuroscience and focuses on the modulation of neuronal excitability and synaptic transmission in both physiological and pathophysiological conditions. This currently takes several directions including the following:
- Identifying novel roles for protease-activated receptor 2 (PAR-2) in the central nervous system (CNS).
- Examining how peripheral inflammation affect CNS function and animal behaviour (with Dr Hui-Rong Jiang)
- Determining the role of Toll-like receptor 3 (TLR3) in the CNS development.
- Investigating the role of mitogen-activated protein kinase phosphatase-2 (MKP2) in the CNS.
- Developing novel microfluidic devices for neuroscience research (with Dr Michele Zagnoni).
A variety of preparations are utilised in our research including mammalian expression systems, cultured neurones, organotypic slice cultures and acute brain slices. Techniques used include cell death assays, electrophysiology, immunocytochemistry, overexpression of fluorescently tagged proteins of interest, molecular biological techniques including site-directed mutagenesis and real time RT-PCR and in collaboration with Professor Judy Pratt we utilise a variety of tests to understand rodent behaviour.
I am involved in teaching both the MPharm and BMS cohorts in numerous classes ranging from 1st to 4th year. In addition I am lead of the recently reformed Neuroscience and Mental Health subgroup.
I am currently the Strathclyde local group representative for the British Neuroscience Association. I am also the BNA Host Society Chair for the FENS Forum to be held in Glasgow in July 2020 and a member of the FENS Executive and Programme committees. I am also a full member of the Society for Neuroscience and a Fellow of the Higher Education Academy.
Doctor of Philosophy, University of Bristol
Award Date: 1 Jan 1997
Bachelor of Science, University of Glasgow
Award Date: 1 Jan 1993
- Cellular Neurophysiology
- 12 Similar Profiles
Dive into details
Select a country/territory to view shared publications and projects
1/10/20 → 1/04/24
Project: Research Studentship - Internally Allocated
An evaluation of multi-excitation-wavelength standing-wave fluorescence microscopy (TartanSW) to improve sampling density in studies of the cell membrane and cytoskeletonSchniete, J. K., Tinning, P. W., Scrimgeour, R. C., Robb, G., Kölln, L. S., Wesencraft, K., Paul, N. R., Bushell, T. J. & McConnell, G., 3 Feb 2021, In: Scientific Reports. 11, 10 p., 2903.
Research output: Contribution to journal › Article › peer-reviewOpen AccessFile6 Downloads (Pure)
Increased levels of IL-16 in the central nervous system during neuroinflammation are associated with infiltrating immune cells and resident glial cellsHridi, S. U., Barbour, M., Wilson, C., Franssen, A. JPM., Harte, T., Bushell, T. J. & Jiang, H-R., 27 May 2021, In: Biology. 10, 6, 15 p., 472.
Research output: Contribution to journal › Article › peer-reviewOpen AccessFile2 Downloads (Pure)
Data for: "An evaluation of multi-excitation-wavelength standing-wave fluorescence microscopy (TartanSW) to improve sampling density in studies of the cell membrane and cytoskeleton"
McConnell, G. (Creator), Schniete, J. K. (Data Collector), Tinning, P. W. (Data Collector), Scrimgeour, R. (Data Collector), Robb, G. (Data Collector), Kölln, L. S. (Data Collector), Wesencraft, K. (Data Collector), Paul, N. (Data Collector) & Bushell, T. (Creator), University of Strathclyde, 24 Nov 2020
6 Jun 2019
Activity: Other activity types › Types of Public engagement and outreach - Media article or participation