• United Kingdom

Accepting PhD Students

Willing to speak to media

  • 527 Citations
20012019
If you made any changes in Pure these will be visible here soon.

Personal profile

Personal Statement

I obtained my BSc (Hons) in Pharmacology from the University of Glasgow (1992) and my PhD in Neuroscience from the University of Bristol (1996) before undertaking postdoctoral research at the University of Chicago and Imperial College London. I took up my position here at Strathclyde in 2002.

My research interest lies primarily in the field of neuroscience and focuses on the modulation of neuronal excitability and synaptic transmission in both physiological and pathophysiological conditions. This currently takes several directions: the role of proteinase-activated receptors in central neurones, the function of MAP kinase phosphatases within the CNS, the G-protein coupled receptor modulation of two-pore K+ channels (K2Ps) and immune cell involvement in neurological disorders. I also collaborate with Dr Michele Zagnoni developing microfluidic devices to enable novel neuroscience research. A variety of preparations are utilised in our research including mammalian expression systems, cultured neurones, organotypic slice cultures and acute brain slices. Techniques used include cell death assays, electrophysiology, immunocytochemistry, overexpression of fluorescently tagged proteins of interest, molecular biological techniques including site-directed mutagenesis and real time RT-PCR and in collaboration with Dr Ros Brett and Professor Judy Pratt we utilise a variety of tests to understand rodent behaviour. 

I am involved in teaching both the MPharm and BMS cohorts in numerous classes ranging from 1st to 4th year.  In addition I am  co-ordinator of the recently formed New Medicines Fundamental research group.

I am currently the Strathclyde local group representative for the British Neuroscience Association as well as being on the organising committee for Glasgow Neuroscience Day. I am also a full member of the Society for Neuroscience and a Fellow of the Higher Education Academy.

Education/Academic qualification

Doctor of Philosophy, University of Bristol

Bachelor of Science, University of Glasgow

Keywords

  • Cellular Neurophysiology
  • Neuropharmacology
  • G-protein coupled receptors
  • Neurodegeneration

Fingerprint Fingerprint is based on mining the text of the person's scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

  • 6 Similar Profiles
PAR-2 Receptor Medicine & Life Sciences
Neurons Medicine & Life Sciences
Microfluidics Medicine & Life Sciences
Proteinase-Activated Receptors Medicine & Life Sciences
Fura-2 Medicine & Life Sciences
seryl-leucyl-isoleucyl-glycyl-arginyl-leucine Medicine & Life Sciences
Induced Pluripotent Stem Cells Medicine & Life Sciences
Cannabidiol Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 2005 2019

Research Output 2001 2018

Open Access
File
illuminators
Fura-2
esters
Esters
light emitting diodes
Autoimmune Experimental Encephalomyelitis
Therapeutic Uses
Anti-Idiotypic Antibodies
Central Nervous System
Spinal Cord

Thesis

An investigation into the role of TLR3 activation on hippocampal function

Author: Ritchie, L., 1 Oct 2015

Supervisor: Bushell, T. (Supervisor) & Paul, A. (Supervisor)

Student thesis: Doctoral Thesis

Activities 2004 2018

FENS Forum of Neuroscience 2020

Bushell, T. (Participant)
14 Jul 201816 Jul 2020

Activity: Organiser of major conference

Federation of European Neuroscience Societies (External organisation)

Bushell, T. (Advisor)
16 Jul 201815 Jul 2020

Activity: Membership of committee