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Personal profile

Personal Statement

I obtained my BSc (Hons) in Pharmacology from the University of Glasgow (1992) and my PhD in Neuroscience from the University of Bristol (1996) before undertaking postdoctoral research at the University of Chicago and Imperial College London. I took up my position here at Strathclyde in 2002.

My research interest lies primarily in the field of neuroscience and focuses on the modulation of neuronal excitability and synaptic transmission in both physiological and pathophysiological conditions. This currently takes several directions: the role of proteinase-activated receptors in central neurones, the function of MAP kinase phosphatases within the CNS, the G-protein coupled receptor modulation of two-pore K+ channels (K2Ps) and immune cell involvement in neurological disorders. I also collaborate with Dr Michele Zagnoni developing microfluidic devices to enable novel neuroscience research. A variety of preparations are utilised in our research including mammalian expression systems, cultured neurones, organotypic slice cultures and acute brain slices. Techniques used include cell death assays, electrophysiology, immunocytochemistry, overexpression of fluorescently tagged proteins of interest, molecular biological techniques including site-directed mutagenesis and real time RT-PCR and in collaboration with Dr Ros Brett and Professor Judy Pratt we utilise a variety of tests to understand rodent behaviour. 

I am involved in teaching both the MPharm and BMS cohorts in numerous classes ranging from 1st to 4th year.  In addition I am  co-ordinator of the recently formed New Medicines Fundamental research group.

I am currently the Strathclyde local group representative for the British Neuroscience Association as well as being on the organising committee for Glasgow Neuroscience Day. I am also a full member of the Society for Neuroscience and a Fellow of the Higher Education Academy.

Education/Academic qualification

Doctor of Philosophy, University of Bristol

Bachelor of Science, University of Glasgow


  • Cellular Neurophysiology
  • Neuropharmacology
  • G-protein coupled receptors
  • Neurodegeneration

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Projects 2005 2021

Research Output 2001 2018

Open Access
light emitting diodes

Fast optical sectioning for widefield fluorescence mesoscopy with the mesolens based on HiLo microscopy

Schniete, J., Franssen, A., Dempster, J., Bushell, T. J., Amos, W. B. & McConnell, G., 2 Nov 2018, In : Scientific Reports. 8, 10 p., 16259

Research output: Contribution to journalArticle

Open Access
field of view


An investigation into the role of TLR3 activation on hippocampal function

Author: Ritchie, L., 1 Oct 2015

Supervisor: Bushell, T. (Supervisor) & Paul, A. (Supervisor)

Student thesis: Doctoral Thesis

Activities 2004 2018

Federation of European Neuroscience Societies (External organisation)

Bushell, T. (Advisor)
16 Jul 201815 Jul 2020

Activity: MembershipMembership of committee

Federation of European Neuroscience Societies (External organisation)

Bushell, T. (Advisor)
16 Jul 201815 Jul 2020

Activity: MembershipMembership of committee