• United Kingdom

Accepting PhD Students

20032024

Research output per year

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Personal profile

Personal Statement

I am a Chancellors Research Fellow, examining the role of mitochondria in the normal function of cells of the brain (neurons, glia and cerebrovasculature), as well as the role that mitochondria play in protecting or contributing to neurodegeneration or dysfunction in disease. Current particular areas of focus include alterations in mitochondrial motility and functionality due to amyloid-β or hyperglycaemia.

 

Find out more about neuroscience research at Strathclyde and view our MSc Neuroscience & Mental Health programme.

 

Research Interests

My primary research interest is in mitochondria, with a particular focus on the involvement of these small organelles with calcium signalling processes and the changes associated with age and diseases. I use high-speed and timelapse fluorescence imaging to visualise and modulate mitochondria and calcium signals within live cells and tissue. 

Teaching Interests

I teach on both the Biomedical Sciences and MPharm degree programs and am course coordinator for the in MSc Neuroscience & Mental Health, as well as module coordinator for year 3 MPharm Management of Cardiovascular Conditions. I host Masters students in the lab - MSc, MSci and MRes projects, in addition to supervising/co-supervising 2 PhD students and 2 EngD students.

 

Find out more about neuroscience research at Strathclyde and view our MSc Neuroscience & Mental Health programme.

 

Expertise & Capabilities

I am the University representative for The Physiological Society (https://www.physoc.org/) - please do contact me with any queries relating to membership, grant applications, conferences or any other aspect of support that the Society offers.

Core lab techniques and capabilities include:

  • primary neuronal / glial / smooth muscle cell isolation and culture
  • live-cell fluorescence imaging (Ca2+, organelle transport, ROS etc)
  • image analysis & quantification

Academic / Professional qualifications

Fellow of the Higher Education Academy

PhD (Dundee / Buck Institute for Age Research, CA)

BSc (Hons) (Aberdeen)

Keywords

  • Mitochondria
  • Calcium
  • Neurodegeneration
  • Vascular smooth muscle
  • Fluorescence microscopy

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Projects

Research Output

MYC regulates fatty acid metabolism through a multigenic program in claudin-low triple negative breast cancer

Casciano, J. C., Perry, C., Cohen-Nowak, A. J., Miller, K. D., Voorde, J. V., Zhang, Q., Chalmers, S., Sandison, M. E., Lui, Q., Hedley, A., McBryan, T., Tang, H-Y., Gorman, N., Beer, T., Speicher, D. W., Adams, P. D., Lui, X., Schlegel, R., McCarron, J. G., Wakelam, M. J. O. & 3 others, Gottlieb, E., Kossenkov, A. V. & Schug, Z. T., 16 Jan 2020, In : British Journal of Cancer. 17 p.

Research output: Contribution to journalArticle

Open Access
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  • 1 Downloads (Pure)

    Mitochondrial motility decreases with cell age, amyloid-β oligomers or hyperglycaemia in hippocampal cells

    Rooney, R., Al-Bazi, S., Kim, S. J., Saunter, C. D. & Chalmers, S., 17 Mar 2019.

    Research output: Contribution to conferencePoster

    Activities

    Career Carousel: opting for a career in science

    Susan Chalmers (Speaker)
    3 Oct 2019

    Activity: Other activity typesTypes of Public engagement and outreach - Media article or participation

    Explorathon 2019 European Researchers Outreach Event

    Susan Chalmers (Presenter)
    23 Sep 2019

    Activity: Other activity typesTypes of Public engagement and outreach - Media article or participation

    Impacts

    Public engagement/education with p4 pupils at Kelvindale Primary School

    Susan Chalmers (Participant)

    Impact: Impact - for External PortalEducation, Public understanding, information and debate