Projects per year
I am a Chancellors Research Fellow, examining the role of mitochondria in the normal function of cells of the brain (neurons, glia and cerebrovasculature), as well as the role that mitochondria play in protecting or contributing to neurodegeneration or dysfunction in disease. Current particular areas of focus include alterations in mitochondrial motility and functionality due to amyloid-β or hyperglycaemia.
My primary research interest is in mitochondria, with a particular focus on the involvement of these small organelles with calcium signalling processes and the changes associated with age and diseases. I use high-speed and timelapse fluorescence imaging to visualise and modulate mitochondria and calcium signals within live cells and tissue.
I teach on both the Biomedical Sciences and MPharm degree programs and am course coordinator for the in MSc Neuroscience & Mental Health, as well as module coordinator for year 3 MPharm Management of Cardiovascular Conditions. I host Masters students in the lab - MSc, MSci and MRes projects, in addition to supervising/co-supervising 2 PhD students and 2 EngD students.
Expertise & Capabilities
I am the University representative for The Physiological Society (https://www.physoc.org/) - please do contact me with any queries relating to membership, grant applications, conferences or any other aspect of support that the Society offers.
Core lab techniques and capabilities include:
- primary neuronal / glial / smooth muscle cell isolation and culture
- live-cell fluorescence imaging (Ca2+, organelle transport, ROS etc)
- image analysis & quantification
Academic / Professional qualifications
Fellow of the Higher Education Academy
PhD (Dundee / Buck Institute for Age Research, CA)
BSc (Hons) (Aberdeen)
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
- Vascular smooth muscle
- Fluorescence microscopy
- 1 Similar Profiles
Dive into details
Select a country/territory to view shared publications and projects
Sunitinib and imatinib display differential cardiotoxicity in adult rat cardiac fibroblasts that involves a role for calcium/calmodulin dependent protein kinase IIMcMullen, C. J., Chalmers, S., Wood, R., Cunningham, M. R. & Currie, S., 1 Feb 2021, In: Frontiers in Cardiovascular Medicine. 7, 15 p., 630480.
Research output: Contribution to journal › Article › peer-reviewOpen AccessFile19 Downloads (Pure)
Chalmers, S., 11 Jul 2020.
Research output: Contribution to conference › Poster › peer-review
25 Nov 2020
Activity: Talk or presentation types › Oral presentation