Projects per year
Personal profile
Personal Statement
I am a Chancellors Research Fellow, examining the role of mitochondria in the normal function of cells of the brain (neurons, glia and cerebrovasculature), as well as the role that mitochondria play in protecting or contributing to neurodegeneration or dysfunction in disease. Current particular areas of focus include alterations in mitochondrial motility and functionality due to amyloid-β or hyperglycaemia.
Research Interests
My primary research interest is in mitochondria, with a particular focus on the involvement of these small organelles with calcium signalling processes and the changes associated with age and diseases. I use high-speed and timelapse fluorescence imaging to visualise and modulate mitochondria and calcium signals within live cells and tissue.
Teaching Interests
I teach on both the Biomedical Sciences and MPharm degree programs and am class co-ordinator for MP323 "Management of Cardiovascular Conditions". I host Masters students in the lab - MSc, MSci and MRes projects, in addition to supervising/co-supervising 2 PhD students and 2 EngD students.
Expertise & Capabilities
I am the University representative for The Physiological Society (https://www.physoc.org/) - please do contact me with any queries relating to membership, grant applications, conferences or any other aspect of support that the Society offers.
Core lab techniques and capabilities include:
- primary neuronal / glial / smooth muscle cell isolation and culture
- live-cell fluorescence imaging (Ca2+, organelle transport, ROS etc)
- image analysis & quantification
Academic / Professional qualifications
Fellow of the Higher Education Academy
PhD (Dundee / Buck Institute for Age Research, CA)
BSc (Hons) (Aberdeen)
Keywords
- Mitochondria
- Calcium
- Neurodegeneration
- Vascular smooth muscle
- Fluorescence microscopy
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Projects 2012 2024
EPSRC Centre for Doctoral Training in Medical Devices and Health Technologies | Lachendro, Flynn James
Coupaud, S., Chalmers, S. & Lachendro, F. J.
EPSRC (Engineering and Physical Sciences Research Council)
1/10/17 → 1/10/21
Project: Research Studentship - Internally Allocated › Research Studentship (Internally Allocated)
Research Output 2003 2019
Mitochondrial motility decreases with cell age, amyloid-β oligomers or hyperglycaemia in hippocampal cells
Rooney, R., Al-Bazi, S., Kim, S. J., Saunter, C. D. & Chalmers, S., 17 Mar 2019.Research output: Contribution to conference › Poster
Multi-omics studies demonstrate Toxoplasma gondii-induced metabolic reprogramming of murine dendritic cells
Hargrave, K. E., Woods, S., Millington, O., Chalmers, S., Westrop, G. D. & Roberts, C. W., 11 Sep 2019, In : Frontiers in Cellular and Infection Microbiology : Parasite and Host. 9, 19 p., 309.Research output: Contribution to journal › Article
Activities 2016 2019
Career Carousel: opting for a career in science
Susan Chalmers (Speaker)Activity: Other activity types › Types of Public engagement and outreach - Media article or participation
Explorathon 2019 European Researchers Outreach Event
Susan Chalmers (Presenter)Activity: Other activity types › Types of Public engagement and outreach - Media article or participation
Impacts
Public engagement/education with p4 pupils at Kelvindale Primary School
Susan Chalmers (Participant)
Impact: Impact - for External Portal › Education, Public understanding, information and debate