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Bioorthogonal Catalysts for Cancer Detection

Personal profile

Personal Statement

I graduated from the University of Queensland (Australia) with a BBiotech (Honours Class I) and PhD in Chemical Sciences under the supervision of Prof. David Fairlie, where I worked on synthetic metalloenzymes, developed helical peptidomimetics, and led drug discovery campaigns against infectious diseases. I joined the group of Prof Luke Odell (Uppsala University, Sweden) as a Carl Tryggers Fellow and developed novel carbonylative transformations using transition metal, photoredox and radical catalysis, and implemented these methods to develop 11C-radiotracers. I then joined the lab of Prof Adam Nelson (Leeds University, UK) and worked on the development of autonomous drug discovery platform. In 2018, I received a MSCA fellowship and joined the University of Edinburgh, where I developed targeted cancer theranostics with Prof Unciti-Broceta, and targeted cancer therapeutics with Prof Liz Patton as a MRC Fellow. In 2022, I joined the Department of Pure and Applied Chemistry as a Chancellor's Fellow.

Research Interests

My research interests are centred on a ‘Catalysis’ theme, and interface computational science, chemistry and biology. My research aims to build next generation bioorthogonal catalysts – by combining nature’s enzymes and synthetic catalysts – to perform advanced biological interrogation in living systems. The long term aims of my research are to develop smarter diagnostic tools for early detection and disease prevention.

Expertise & Capabilities

  • synthetic chemisty
  • transition metal catalysis
  • peptidomimetics
  • radiochemistry
  • high-throughput experimentation
  • chemical biology
  • molecular imaging
  • positron emission tomography

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being

Education/Academic qualification

Doctor of Philosophy, PhD in Chemical Sciences, University of Queensland

Award Date: 24 Apr 2014

Bachelor of Science, Bachelor of Chemical Biotechnology (Honours Class 1), University of Queensland

Award Date: 6 Dec 2009

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