• United Kingdom

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PhD projects

Bioorthogonal Catalysts for Cancer Detection

Personal profile

Personal Statement

I graduated from the University of Queensland (Australia) with a BBiotech (Honours Class I) and PhD in Chemical Sciences under the supervision of Prof. David Fairlie, where I worked on synthetic metalloenzymes, developed helical peptidomimetics, and led drug discovery campaigns against infectious diseases. I joined the group of Prof Luke Odell (Uppsala University, Sweden) as a Carl Tryggers Fellow and developed novel carbonylative transformations using transition metal, photoredox and radical catalysis, and implemented these methods to develop 11C-radiotracers. I then joined the lab of Prof Adam Nelson (Leeds University, UK) and worked on the development of autonomous drug discovery platform. In 2018, I received a MSCA fellowship and joined the University of Edinburgh, where I developed targeted cancer theranostics with Prof Unciti-Broceta, and targeted cancer therapeutics with Prof Liz Patton as a MRC Fellow. In 2022, I joined the Department of Pure and Applied Chemistry as a Chancellor's Fellow.

Research Interests

My research interests are centred on a ‘Catalysis’ theme, and interface computational science, chemistry and biology. My research aims to build next generation bioorthogonal catalysts – by combining nature’s enzymes and synthetic catalysts – to perform advanced biological interrogation in living systems. The long term aims of my research are to develop smarter diagnostic tools for early detection and disease prevention.

Expertise & Capabilities

  • synthetic chemisty
  • transition metal catalysis
  • peptidomimetics
  • radiochemistry
  • high-throughput experimentation
  • chemical biology
  • molecular imaging
  • positron emission tomography

Education/Academic qualification

Doctor of Philosophy, PhD in Chemical Sciences, University of Queensland

Award Date: 24 Apr 2014

Bachelor of Science, Bachelor of Chemical Biotechnology (Honours Class 1), University of Queensland

Award Date: 6 Dec 2009

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