Projects per year
Personal profile
Personal Statement
I graduated from the University of Queensland (Australia) with a BBiotech (Honours Class I) and PhD in Chemical Sciences under the supervision of Prof. David Fairlie, where I worked on synthetic metalloenzymes, developed helical peptidomimetics, and led drug discovery campaigns against infectious diseases. I joined the group of Prof Luke Odell (Uppsala University, Sweden) as a Carl Tryggers Fellow and developed novel carbonylative transformations using transition metal, photoredox and radical catalysis, and implemented these methods to develop 11C-radiotracers. I then joined the lab of Prof Adam Nelson (Leeds University, UK) and worked on the development of autonomous drug discovery platform. In 2018, I received a MSCA fellowship and joined the University of Edinburgh, where I developed targeted cancer theranostics with Prof Unciti-Broceta, and targeted cancer therapeutics with Prof Liz Patton as a MRC Fellow. In 2022, I joined the Department of Pure and Applied Chemistry as a Chancellor's Fellow.
Research Interests
My research interests are centred on a ‘Catalysis’ theme, and interface computational science, chemistry and biology. My research aims to build next generation bioorthogonal catalysts – by combining nature’s enzymes and synthetic catalysts – to perform advanced biological interrogation in living systems. The long term aims of my research are to develop smarter diagnostic tools for early detection and disease prevention.
Expertise & Capabilities
- synthetic chemisty
- transition metal catalysis
- peptidomimetics
- radiochemistry
- high-throughput experimentation
- chemical biology
- molecular imaging
- positron emission tomography
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Doctor of Philosophy, PhD in Chemical Sciences, University of Queensland
Award Date: 24 Apr 2014
Bachelor of Science, Bachelor of Chemical Biotechnology (Honours Class 1), University of Queensland
Award Date: 6 Dec 2009
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Collaborations and top research areas from the last five years
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Industrial CASE Account - University of Strathclyde 2024 | O'Brien, Megan
Jamieson, C. (Principal Investigator), Chow, S. (Co-investigator) & O'Brien, M. (Research Co-investigator)
EPSRC (Engineering and Physical Sciences Research Council)
1/10/24 → 1/10/28
Project: Research Studentship Case - Internally allocated
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GLAS-CYTO: AN INTEGRATED FACILITY FOR THE BIOPHYSICAL ANALYSIS OF CELLULAR INTERACTIONS
Burley, G. (Principal Investigator), Chamberlain, L. (Co-investigator), Chow, S. (Co-investigator), Corrigan, D. (Co-investigator), Cunningham, M. R. (Co-investigator), Faulds, K. (Co-investigator), Jamieson, C. (Co-investigator), Rattray, Z. (Co-investigator), Tomkinson, N. (Co-investigator) & Taladriz Sender, A. (Research Co-investigator)
BBSRC (Biotech & Biological Sciences Research Council)
1/08/24 → 31/07/25
Project: Research
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Cancer-targeting upconversion nanoparticles to track-and-treat glioblastoma
Connelly, C. & Chow, S., 14 Jun 2024.Research output: Contribution to conference › Poster
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Targeted molecular construct for bioorthogonal theranostics of PD-L1-expressing cancer cells
Chow, S. Y. & Unciti-Broceta, A., 1 Jul 2022, In: JACS Au. 2, 7, p. 1747–1756 10 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile5 Citations (Scopus)2 Downloads (Pure)
Prizes
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Wellcome Trust iTPA Springboard Award
CHOW, S. (Recipient), 2021
Prize: Prize (including medals and awards)
Activities
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Scottish Research Showcase - Explorathon 22
CHOW, S. (Recipient)
3 Nov 2022Activity: Public Engagement and Outreach › Media Participation
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RSC Research Enablement Grant Peer Review (Event)
Chow, S. (Peer reviewer)
Aug 2024 → …Activity: Publication peer-review and editorial work types › To be assigned