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1993 …2020

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2020

Metabolomics-guided isolation of anti-trypanosomal compounds from endophytic fungi of the mangrove plant Avicennia lanata

Mazlan, N. W., Tate, R., Yusoff, Y. M., Clements, C. & Edrada-Ebel, R., 1 Jan 2020, In : Current Medicinal Chemistry. 27, 11, p. 1815-1835 21 p.

Research output: Contribution to journalArticle

Open Access
File
4 Citations (Scopus)
7 Downloads (Pure)
2019

Camptothecin-based dendrimersomes for gene delivery and redox-responsive drug delivery to cancer cells

Laskar, P., Somani, S., Campbell, S. J., Mullin, M., Keating, P., Tate, R. J., Irving, C., Leung, H. Y. & Dufès, C., 14 Nov 2019, In : Nanoscale. 11, 42, p. 20058-20071 14 p.

Research output: Contribution to journalArticle

Open Access
File
4 Citations (Scopus)

Whole genome microarray analysis of DUSP4-deletion reveals a novel role for MAP kinase phosphatase-2 (MKP-2) in macrophage gene expression and function

Neamatallah, T., Jabbar, S., Tate, R., Schroeder, J., Shweash, M., Alexander, J. & Plevin, R., 12 Jul 2019, In : International Journal of Molecular Sciences. 20, 14, 17 p., 3434.

Research output: Contribution to journalArticle

Open Access
File
1 Citation (Scopus)
18 Downloads (Pure)
2018
Open Access
File
13 Downloads (Pure)

Disruption of the Zdhhc9 intellectual disability gene leads to behavioural abnormalities in a mouse

Kouskou, M., Thomson, D. M., Brett, R. R., Wheeler, L., Tate, R. J., Pratt, J. A. & Chamberlain, L. H., 31 Oct 2018, In : Experimental Neurology. 308, p. 35-46 12 p.

Research output: Contribution to journalArticle

Open Access
File
4 Citations (Scopus)
33 Downloads (Pure)

Native and polyubiquitinated forms of dihydroceramide desaturase are differentially linked to human embryonic kidney cell survival

Alsanafi, M., Kelly, S. L., Jubair, K., McNaughton, M., Tate, R. J., Merrill Jr., A. H., Pyne, S. & Pyne, N. J., 13 Nov 2018, In : Molecular and Cellular Biology. 38, 18 p., e00222.

Research output: Contribution to journalArticle

Open Access
File
6 Citations (Scopus)
10 Downloads (Pure)
Open Access
File
12 Downloads (Pure)

Redox-sensitive, cholesterol-bearing PEGylated poly(propyleneimine)-based dendrimersomes for drug and gene delivery to cancer cells

Laskar, P., Somani, S., Altwaijry, N. A. S., Mullin, M., Bowering, D., Warzecha, M., Keating, P., Tate, R. J., Leung, H. Y. & Dufès, C., 28 Dec 2018, In : Nanoscale. 10, 48, p. 22830-22847 18 p.

Research output: Contribution to journalArticle

Open Access
File
11 Citations (Scopus)
5 Downloads (Pure)

Regression of prostate tumors after intravenous administration of lactoferrin-bearing polypropylenimine dendriplexes encoding TNF-α, TRAIL and interleukin-12

Altwaijry, N., Somani, S., Parkinson, J. A., Tate, R. J., Keating, P., Warzecha, M., MacKenzie, G. R., Leung, H. Y. & Dufès, C., 1 Mar 2018, In : Drug Delivery. 25, 1, p. 679-689 11 p.

Research output: Contribution to journalArticle

Open Access
File
16 Citations (Scopus)
49 Downloads (Pure)
Open Access
File
5 Citations (Scopus)
22 Downloads (Pure)
16 Citations (Scopus)
34 Downloads (Pure)

Toll-like receptor 3 activation impairs excitability and synaptic activity via TRIF signalling in immature rat and human neurons

Ritchie, L., Tate, R., Chamberlain, L. H., Robertson, G., Zagnoni, M., Sposito, T., Wray, S., Wright, J. A., Bryant, C. E., Gay, N. J. & Bushell, T. J., 30 Jun 2018, In : Neuropharmacology. 135, p. 1-10 10 p.

Research output: Contribution to journalArticle

Open Access
File
7 Citations (Scopus)
13 Downloads (Pure)
2017
13 Citations (Scopus)
29 Downloads (Pure)

Etoposide upregulates survival favoring sphingosine-1-phosphate in etoposide-resistant retinoblastoma cells

Kakkassery, V., Skosyrski, S., Lüth, A., Kleuser, B., van der Giet, M., Tate, R., Reinhard, J., Faissner, A., Joachim, S. C. & Kociok, N., 15 Nov 2017, In : Pathology & Oncology Research. 9 p.

Research output: Contribution to journalArticle

Open Access
File
3 Citations (Scopus)
8 Downloads (Pure)
Open Access
File
16 Citations (Scopus)
29 Downloads (Pure)

Metabolomic tools to assess the chemistry and bioactivity of endophytic aspergillus strain

Tawfike, A. F., Tate, R., Abbott, G., Young, L., Viegelmann, C., Schumacher, M., Diederich, M. & Edrada-Ebel, R. A., 3 Jul 2017, In : Chemistry and Biodiversity.

Research output: Contribution to journalArticle

Open Access
File
15 Citations (Scopus)
112 Downloads (Pure)
23 Citations (Scopus)
115 Downloads (Pure)
Open Access
File
6 Citations (Scopus)
95 Downloads (Pure)
2015
44 Citations (Scopus)
68 Downloads (Pure)

Effects of CoCr metal wear debris generated from metal-on-metal hip implants and Co ions on human monocyte-like U937 cells

Posada, O. M., Tate, R. J. & Grant, M. H., Mar 2015, In : Toxicology in Vitro. 29, 2, p. 271-280 10 p.

Research output: Contribution to journalArticle

Open Access
File
27 Citations (Scopus)
158 Downloads (Pure)
Open Access
File
16 Citations (Scopus)
76 Downloads (Pure)
Open Access
File
22 Citations (Scopus)
110 Downloads (Pure)

Tumor regression following intravenous administration of lactoferrin- and lactoferricin-bearing dendriplexes

Lim, L. Y., Koh, P. Y., Somani, S., Al Robaian, M., Karim, R., Yean, Y. L., Mitchell, J., Tate, R. J., Edrada-Ebel, R., Blatchford, D. R., Mullin, M. & Dufès, C., Aug 2015, In : Nanomedicine: Nanotechnology, Biology and Medicine. 11, p. 1445-1454 10 p.

Research output: Contribution to journalArticle

Open Access
File
28 Citations (Scopus)
276 Downloads (Pure)
2014
Open Access
File
21 Citations (Scopus)
153 Downloads (Pure)
2013

The p.Arg86Gln change in GARP2 (glutamic acid-rich protein-2) is a common West African-related polymorphism

Gibriel, A., Tate, R., Yu, Y., Rawson-Lax, E., Hammer, HM., Tettey, J. N. A., Pyne, N. & Converse, C., 15 Feb 2013, In : Gene. 515, 1, p. 155-158 4 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

The sphingosine kinase inhibitor 2-(p-hyroxyanilino)-4-(p-chlorophenyl)thiazole reduces androgen receptor expression via an oxidative stress-dependent mechanism

Tonelli, F., Alossaimi, M., Williamson, L., Tate, R. J., Watson, D. G., Chan, E., Bittman, R., Pyne, N. J. & Pyne, S., 1 Mar 2013, In : British Journal of Pharmacology. 168, 6, p. 1497-1505 9 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)
2012
14 Citations (Scopus)

Tumor regression following intravenous administration of a tumor-targeted p73 gene delivery system

Lemarié, F., Croft, D., Tate, R., Ryan, K. M. & Dufès, C., 2012, In : Biomaterials. 33, p. 2701-2709 9 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)
2011

Enhanced gene expression in tumors after intravenous administration of arginine-, lysine- and leucine-bearing polyethylenimine polyplex

Aldawsari, H. M., Sundara Raj, B., Edrada-Ebel, R., Blatchford, D., Tate, R., Tetley, L. & Dufès, C., 2011, In : Nanomedicine: Nanotechnology, Biology and Medicine. 7, 5, p. 815-823 9 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)

Enhanced gene expression in tumors after intravenous administration of arginine-, lysine- and leucine-bearing polypropylenimine polyplex

Aldawsari, H. M., Edrada-Ebel, R., Blatchford, D., Tate, R., Tetley, L. & Dufès, C., Sep 2011, In : Biomaterials. 32, 25, p. 5889-5899 11 p.

Research output: Contribution to journalArticle

41 Citations (Scopus)
6 Downloads (Pure)
2010

Enhanced transfection efficacy of polyethylenimine by surface modification with arginine, lysine, and leucine

Aldawsari, H. M., Sundara Raj, B., Edrada-Ebel, R., Blatchford, D., Tate, R. & Dufès, C., 2010, In : Controlled Release Society Newsletter. 27, 6, p. 12-14 3 p.

Research output: Contribution to journalArticle

The sphingosine kinase 1 inhibitor 2-(P-hydroxyanilino)-4-(P-chlorophenyl)thiazole induces proteasomal degradation of sphingosine kinase 1 in mammalian cells

Loveridge, C., Tonelli, F., Leclercq, T., Lim, K. G., Long, J. S., Berdyshev, E., Tate, R. J., Natarajan, V., Pitson, S. M., Pyne, N. J. & Pyne, S., 10 Dec 2010, In : Journal of Biological Chemistry . 285, 50, p. 38841-38852 12 p.

Research output: Contribution to journalArticle

90 Citations (Scopus)

Tumor regression after systemic administration of a novel tumor-targeted gene delivery system carrying a therapeutic plasmid DNA

Koppu, S., Oh, Y. J., Edrada-Ebel, R., Blatchford, D. R., Tetley, L., Tate, R. & Dufès, C., 19 Apr 2010, In : Journal of Controlled Release. 143, 2, p. 215-221 7 p.

Research output: Contribution to journalArticle

75 Citations (Scopus)
3 Downloads (Pure)
2009
26 Citations (Scopus)
2008

Mechanisms underlying the metabolic actions of galegine that contribute to weight loss in mice

Mooney, M. H., Fogarty, S., Stevenson, C., Gallagher, A. M., Palit, P., Hawley, S. A., Hardie, D. G., Coxon, G., Waigh, R., Tate, R., Harvey, A. & Furman, B., Apr 2008, In : British Journal of Pharmacology. 153, 8, p. 1669-1677 9 p.

Research output: Contribution to journalArticle

45 Citations (Scopus)
2007
3 Citations (Scopus)
2006

Lack of immunological cross-reactivity between parasite-derived and recombinant forms of es-62, a secreted protein of acanthocheilonema viteae

Egan, C. A., Houston, K. M., Alcocer, M. J. C., Solovyova, A., Tate, R., Lochnit, G., McInnes, I. B. & Harnett, M. M., Feb 2006, In : Parasitology. 132, 2, p. 263-274 11 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)
2003

Interaction of caspase-3 with the cyclic GMP binding cyclic GMP specific phosphodiesterase (PDE5a1)

Frame, M. J., Tate, R., Adams, D. R., Morgan, K. M., Houslay, M. D., Vandenabeele, P. & Pyne, N. J., Mar 2003, In : European Journal of Biochemistry . 270, 5, p. 962-970 9 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)
19 Citations (Scopus)

Two-pore domain k channel, TASK-1, in pulmonary artery smooth muscle cells

Gurney, A. M., Osipenko, O. N., MacMillan, D., McFarlane, K. M., Tate, R. J. S. J. & Kempsill, F. E. J., 2003, In : Circulation Research. 93, p. 957-964 8 p.

Research output: Contribution to journalArticle

139 Citations (Scopus)
2002

Expression of the filarial nematode phosphorylcholine-containing glycoprotein, ES62, is stage specific

Stepek, G., Auchie, M., Tate, R., Watson, K., Russell, D. G., Devaney, E. & Harnett, W., 2002, In : Parasitology. 125, Pt 2, p. 155-64 10 p.

Research output: Contribution to journalArticle

31 Citations (Scopus)

Properties of the cellular prion protein expressed in Xenopus oocytes

Connolly, J. G., Tate, R. J., McLennan, N. F., Brown, D., Telling, G. C., Fraser, J. & Head, M. W., 2002, In : NeuroReport. 13, 9, p. 1229-1233 4 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
2001
27 Citations (Scopus)
10 Citations (Scopus)
64 Citations (Scopus)
2000
27 Citations (Scopus)

Potential role for kv3.1b channels as oxygen sensors

Osipenko, O. N., Tate, R. J., Gurney, A. M. & Tate, R., 2000, In : Circulation Research. 86, 5, p. 534-40 7 p.

Research output: Contribution to journalArticle

112 Citations (Scopus)
1999

Molecular cloning of magnesium-independent type 2 phosphatidic acid phosphatases from airway smooth muscle

Tate, R. J., Tolan, D. & Pyne, S., 1999, In : Cellular Signalling. 11, 7, p. 515-522 8 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)