1993 …2020
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Research Output 1993 2019

7 Citations (Scopus)

Regression of prostate tumors after intravenous administration of lactoferrin-bearing polypropylenimine dendriplexes encoding TNF-α, TRAIL and interleukin-12

Altwaijry, N., Somani, S., Parkinson, J. A., Tate, R. J., Keating, P., Warzecha, M., MacKenzie, G. R., Leung, H. Y. & Dufès, C., 1 Mar 2018, In : Drug Delivery. 25, 1, p. 679-689 11 p.

Research output: Contribution to journalArticle

Open Access
File
Lactoferrin
Interleukin-12
Intravenous Administration
Prostate
Tumor Necrosis Factor-alpha
5 Citations (Scopus)

Regulation of lipid metabolism by microRNAs

Tate, R., Rotondo, D. & Davidson, J., 10 Jun 2015, In : Current Opinion in Lipidology. 26, 3, p. 243-244 2 p.

Research output: Contribution to journalEditorial

Open Access
File

RNA stability in frozen/thawed clinical blood samples

Posada Estefan, O. M., Tate, R. & Grant, M., 2011, p. 9. 1 p.

Research output: Contribution to conferenceAbstract

RNA Stability
RNA
Gene Expression

RNA stability in frozen/thawed clinical samples

Posada Estefan, O. M., Tate, R. & Grant, M., Aug 2011.

Research output: Contribution to conferencePoster

Posters
RNA Stability
24 Citations (Scopus)
Coordination Complexes
Platinum
Drug delivery
Cytotoxicity
Pharmaceutical Preparations
83 Citations (Scopus)
1-Phosphatidylinositol 4-Kinase
Mitogen-Activated Protein Kinase 1
Phosphatidylinositols
Mitogen-Activated Protein Kinases
Smooth Muscle
16 Citations (Scopus)
Open Access
File
Microfluidics
Surface-Active Agents
HEPES
Lipids
Tromethamine
14 Citations (Scopus)

The gamma-subunit of the rod photoreceptor cGMP-binding cGMP-specific PDE is expressed in mouse lung

Tate, R. J., Lochhead, A., Brzeski, H., Arshavsky, V. & Pyne, N. J., 1998, In : Cell Biochemistry and Biophysics. 29, 1-2, p. 133-144 12 p.

Research output: Contribution to journalArticle

Type 6 Cyclic Nucleotide Phosphodiesterases
Type 5 Cyclic Nucleotide Phosphodiesterases
Retinal Rod Photoreceptor Cells
Enzyme Inhibitors
Hydrolysis
10 Citations (Scopus)
Type 6 Cyclic Nucleotide Phosphodiesterases
Type 5 Cyclic Nucleotide Phosphodiesterases
Retinal Rod Photoreceptor Cells
Phosphoric Diester Hydrolases
Caspase 3
11 Citations (Scopus)
Vertebrate Photoreceptor Cells
Cyclic GMP
Phosphoric Diester Hydrolases
Lung
Messenger RNA
19 Citations (Scopus)
Type 6 Cyclic Nucleotide Phosphodiesterases
Mitogen-Activated Protein Kinase 1
Phosphoric Diester Hydrolases
Mitogen-Activated Protein Kinases
Epidermal Growth Factor
60 Citations (Scopus)
Mitogen-Activated Protein Kinase 1
Cyclic GMP
Phosphoric Diester Hydrolases
G-Protein-Coupled Receptor Kinase 2
Mitogen-Activated Protein Kinases
2 Citations (Scopus)

The p.Arg86Gln change in GARP2 (glutamic acid-rich protein-2) is a common West African-related polymorphism

Gibriel, A., Tate, R., Yu, Y., Rawson-Lax, E., Hammer, HM., Tettey, J. N. A., Pyne, N. & Converse, C., 15 Feb 2013, In : Gene. 515, 1, p. 155-158 4 p.

Research output: Contribution to journalArticle

Retinitis Pigmentosa
Glutamic Acid
Exons
Mutation
Proteins
Open Access
File
Receptors, Prostaglandin E, EP4 Subtype
Prostaglandin Receptors
Dinoprostone
Tumor Necrosis Factor-alpha
Cytokines
3 Citations (Scopus)
Neuromuscular Blocking Agents
Nicotinic Receptors
Ligands
Amino Acids
Muscles
7 Citations (Scopus)
Open Access
File
Lysosphingolipid Receptors
Exosomes
Extracellular Signal-Regulated MAP Kinases
Fibroblasts
Breast Neoplasms
82 Citations (Scopus)

The sphingosine kinase 1 inhibitor 2-(P-hydroxyanilino)-4-(P-chlorophenyl)thiazole induces proteasomal degradation of sphingosine kinase 1 in mammalian cells

Loveridge, C., Tonelli, F., Leclercq, T., Lim, K. G., Long, J. S., Berdyshev, E., Tate, R. J., Natarajan, V., Pitson, S. M., Pyne, N. J. & Pyne, S., 10 Dec 2010, In : Journal of Biological Chemistry . 285, 50, p. 38841-38852 12 p.

Research output: Contribution to journalArticle

Thiazoles
Cells
Degradation
Androgens
Apoptosis
15 Citations (Scopus)

The sphingosine kinase inhibitor 2-(p-hyroxyanilino)-4-(p-chlorophenyl)thiazole reduces androgen receptor expression via an oxidative stress-dependent mechanism

Tonelli, F., Alossaimi, M., Williamson, L., Tate, R. J., Watson, D. G., Chan, E., Bittman, R., Pyne, N. J. & Pyne, S., 1 Mar 2013, In : British Journal of Pharmacology. 168, 6, p. 1497-1505 9 p.

Research output: Contribution to journalArticle

Thiazoles
Androgen Receptors
Oxidative Stress
Prostatic Neoplasms
sphingosine kinase
4 Citations (Scopus)

Toll-like receptor 3 activation impairs excitability and synaptic activity via TRIF signalling in immature rat and human neurons

Ritchie, L., Tate, R., Chamberlain, L. H., Robertson, G., Zagnoni, M., Sposito, T., Wray, S., Wright, J. A., Bryant, C. E., Gay, N. J. & Bushell, T. J., 30 Jun 2018, In : Neuropharmacology. 135, p. 1-10 10 p.

Research output: Contribution to journalArticle

Open Access
File
Toll-Like Receptor 3
Poly I-C
Neurons
Induced Pluripotent Stem Cells
Miniature Postsynaptic Potentials
19 Citations (Scopus)

Toxicity of cobalt-chromium nanoparticles released from a resurfacing hip implant and cobalt ions on primary human lymphocytes in vitro

Posada, O. M., Tate, R. J. & Grant, M. H., 6 Jun 2015, In : Journal of Applied Toxicology. 35, 6, p. 614-622 9 p.

Research output: Contribution to journalArticle

Open Access
File
Lymphocytes
Chromium
Cobalt
Debris
Nanoparticles
3 Citations (Scopus)
Open Access
File
Fatigue
Healthy Volunteers
Fatigue of materials
athletic performance
rehabilitation (people)
92 Citations (Scopus)

Trypsin stimulates proteinase-activated receptor-2-dependent and -independent activation of mitogen-activated protein kinases

Belham, C. M., Tate, R. J., Scott, P. H., Pemberton, A. D., Miller, H. R., Wadsworth, R. M., Gould, G. W. & Plevin, R., 1996, In : Biochemical journal. 320 ( Pt 3), p. 939-46 8 p.

Research output: Contribution to journalArticle

PAR-2 Receptor
seryl-leucyl-isoleucyl-glycyl-arginyl-leucine
Mitogen-Activated Protein Kinases
Trypsin
Chemical activation
74 Citations (Scopus)

Tumor regression after systemic administration of a novel tumor-targeted gene delivery system carrying a therapeutic plasmid DNA

Koppu, S., Oh, Y. J., Edrada-Ebel, R., Blatchford, D. R., Tetley, L., Tate, R. & Dufès, C., 19 Apr 2010, In : Journal of Controlled Release. 143, 2, p. 215-221 7 p.

Research output: Contribution to journalArticle

Gene Transfer Techniques
Plasmids
DNA
Intravenous Administration
Transferrin
24 Citations (Scopus)

Tumor regression following intravenous administration of a tumor-targeted p73 gene delivery system

Lemarié, F., Croft, D., Tate, R., Ryan, K. M. & Dufès, C., 2012, In : Biomaterials. 33, p. 2701-2709 9 p.

Research output: Contribution to journalArticle

Gene Transfer Techniques
Intravenous Administration
Tumors
Genes
Dendrimers
21 Citations (Scopus)

Tumor regression following intravenous administration of lactoferrin- and lactoferricin-bearing dendriplexes

Lim, L. Y., Koh, P. Y., Somani, S., Al Robaian, M., Karim, R., Yean, Y. L., Mitchell, J., Tate, R. J., Edrada-Ebel, R., Blatchford, D. R., Mullin, M. & Dufès, C., Aug 2015, In : Nanomedicine: Nanotechnology, Biology and Medicine. 11, p. 1445-1454 10 p.

Research output: Contribution to journalArticle

Open Access
File
Bearings (structural)
Lactoferrin
Intravenous Administration
Tumors
Dendrimers
132 Citations (Scopus)

Two-pore domain k channel, TASK-1, in pulmonary artery smooth muscle cells

Gurney, A. M., Osipenko, O. N., MacMillan, D., McFarlane, K. M., Tate, R. J. S. J. & Kempsill, F. E. J., 2003, In : Circulation Research. 93, p. 957-964 8 p.

Research output: Contribution to journalArticle

Membrane Potentials
Pulmonary Artery
Smooth Muscle Myocytes
Lung
Blood Vessels
1 Citation (Scopus)

Whole genome microarray analysis of DUSP4-deletion reveals a novel role for MAP kinase phosphatase-2 (MKP-2) in macrophage gene expression and function

Neamatallah, T., Jabbar, S., Tate, R., Schroeder, J., Shweash, M., Alexander, J. & Plevin, R., 12 Jul 2019, In : International Journal of Molecular Sciences. 20, 14, 17 p., 3434.

Research output: Contribution to journalArticle

Open Access
File
deletion
phosphatases
macrophages
genome
Macrophages