Projects per year
Rebecca is a Chancellor’s Fellow and UKRI Future Leaders Fellow who joined the University of Strathclyde in June 2020. She obtained a BSc in biochemistry and chemistry from the University of Leeds in 2011 and completed her PhD at the University of Manchester in 2015. Rebecca spent 4 years at the Institute for Molecular Pathology in Vienna, Austria as a postdoctoral researcher/ Lise Meitner Postdoctoral Fellow. Throughout her career, she has collected experience in a plethora of mass spectrometry methods to study protein structure such as native mass spectrometry, ion mobility, hydrogen-deuterium exchange, and crosslinking.
Rebecca’s current research is centered around the development of native ion mobility mass spectrometry methods to study proteins and protein complexes, particularly those that are challenging to study with conventional biochemistry methods. Such systems include intrinsically disordered proteins that exist in a wide range of different shapes, and protein complexes formed by protein-degrading molecules such as PROTACs, the complex binding modes of which are challenging to delineate.
- mass spectrometry
- ion mobility
- intrinsically disordered proteins
- protein degraders
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Identifying chemical probes to characterise intrinsically disordered drug targets through novel ion mobility-based screening capabilities
1/10/21 → 31/03/25
Project: Research - Studentship
1/01/21 → 1/07/24
Project: Research Studentship - Internally Allocated
Structural proteomics methods to interrogate the conformation and dynamics of intrinsically disordered proteinsBeveridge, R. & Calabrese, A. N., 11 Mar 2021, In: Frontiers in Chemistry. 9, 20 p., 603639.
Research output: Contribution to journal › Review article › peer-reviewOpen AccessFile22 Downloads (Pure)
A cross-kingdom conserved ER-phagy receptor maintains endoplasmic reticulum homeostasis during stressStephani, M., Picchianti, L., Gajic, A., Beveridge, R., Skarwan, E., Sanchez de Medina Hernandez, V., Mohseni, A., Clavel, M., Zeng, Y., Naumann, C., Matuszkiewicz, M., Turco, E., Loefke, C., Li, B., Dürnberger, G., Schutzbier, M., Chen, H. T., Abdrakhmanov, A., Savova, A., Chia, K-S. & 9 others, , 27 Aug 2020, In: eLife. 9, 50 p., e58396.
Research output: Contribution to journal › Article › peer-reviewOpen AccessFile1 Downloads (Pure)