Research output per year
Research output per year
- 1 - 50 out of 66 results
Search results
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2023
Silk bioconjugates: from concept to application
Matthew, S. A. L. & Seib, F. P., 27 Jan 2023, (E-pub ahead of print) In: ACS Biomaterials Science & Engineering. 17 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile5 Downloads (Pure) -
2022
Erratum: Mixing and flow-induced nanoprecipitation for morphology control of silk fibroin self-assembly
Matthew, S. A. L., Rezwan, R., Kaewchuchuen, J., Perrie, Y. & Seib, F. P., 7 Sept 2022, (E-pub ahead of print) In: RSC Advances. 12, 38, p. 25006-25009 4 p.Research output: Contribution to journal › Comment/debate › peer-review
Open AccessFile3 Downloads (Pure) -
Smart silk origami as eco-sensors for environmental pollution
Matthew, S. A. L., Egan, G., Witte, K., Kaewchuchuen, J., Phuagkhaopong, S., Totten, J. D. & Seib, F. P., 15 Aug 2022, In: ACS Applied Bio Materials. 5, 8, p. 3658-3666 9 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Citations (Scopus)9 Downloads (Pure) -
Volumetric scalability of microfluidic and semi-batch silk nanoprecipitation methods
Matthew, S. A. L., Rezwan, R., Perrie, Y. & Seib, F. P., 6 Apr 2022, In: Molecules. 27, 7, 27 p., 2368.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)20 Downloads (Pure) -
Impact of silk hydrogel secondary structure on hydrogel formation, silk leaching and in vitro response
Egan, G., Phuagkhaopong, S., Matthew, S. A. L., Connolly, P. & Seib, F. P., 8 Mar 2022, In: Scientific Reports. 12, 12 p., 3729.Research output: Contribution to journal › Article › peer-review
Open AccessFile4 Citations (Scopus)14 Downloads (Pure) -
Mixing and flow-induced nanoprecipitation for morphology control of silk fibroin self-assembly
Matthew, S. A. L., Rezwan, R., Kaewchuchuen, J., Perrie, Y. & Seib, F. P., 4 Mar 2022, In: RSC Advances. 12, 12, p. 7357-7373 17 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Citations (Scopus)19 Downloads (Pure) -
Investigation of chip formation mechanism in ultra-precision diamond turning of silk fibroin film
Wang, Z., Luo, X., Sun, J., Seib, P., Phuagkhaopong, S., Chang, W., Gao, J., Mir, A. & Cox, A., 28 Feb 2022, In: Journal of Manufacturing Processes. 74, p. 14-27 14 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Citations (Scopus)4 Downloads (Pure) -
2021
Towards clinical translation of 'second-generation' regenerative stroke therapies: hydrogels as game changers?
Totten, J. D., Alhadrami, H. A., Jiffri, E. H., McMullen, C., Seib, F. P. & Carswell, H. V. O., 20 Nov 2021, (E-pub ahead of print) In: Trends in Biotechnology. 41 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Citations (Scopus)4 Downloads (Pure) -
The innate immune response of self-assembling silk fibroin hydrogels
Gorenkova, N., Maitz, M. F., Böhme, G., Alhadrami, H. A., Jiffri, E. H., Totten, J. D., Werner, C., Carswell, H. V. O. & Seib, F. P., 7 Nov 2021, In: Biomaterials Science. 9, 21, p. 7194-7204 11 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile8 Citations (Scopus)28 Downloads (Pure) -
Silk hydrogel substrate stress relaxation primes mesenchymal stem cell behavior in 2D
Phuagkhaopong, S., Mendes, L., Müller, K., Wobus, M., Bornhäuser, M., Carswell, H. V. O., Duarte, I. F. & Seib, F. P., 7 Jul 2021, In: ACS Applied Materials and Interfaces. 13, 26, p. 30420-30433 14 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile13 Citations (Scopus)25 Downloads (Pure) -
Bioinspired and bioinstructive surfaces to control mesenchymal stem cells
Witte, K., Luo, J., Walker, M., Cantini, M., Seib, F. P. & Salmeron-Sanchez, M., 11 Jun 2021, Soft Matter for Biomedical Applications. Azevedo, H. S., Mano, J. F. & Borges, J. (eds.). Croydon: Royal Society of Chemistry, p. 301-325 25 p. (RSC Soft Matter; vol. 2021-January, no. 13).Research output: Chapter in Book/Report/Conference proceeding › Chapter
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Emerging silk material trends: repurposing, phase separation and solution-based designs
Seib, F. P., 1 Mar 2021, In: Materials. 14, 5, 11 p., 1160.Research output: Contribution to journal › Article › peer-review
Open AccessFile5 Citations (Scopus)55 Downloads (Pure) -
2020
Silk nanoparticle manufacture in semi-batch format
Matthew, S. A. L., Totten, J. D., Phuagkhaopong, S., Egan, G., Witte, K., Perrie, Y. & Seib, F. P., 14 Dec 2020, In: ACS Biomaterials Science & Engineering. 6, 12, p. 6748-6759 12 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile7 Citations (Scopus)32 Downloads (Pure) -
Focal drug administration via heparin-containing cryogel microcarriers reduces cancer growth and metastasis
Newland, B., Varricchio, C., Körner, Y., Hoppe, F., Taplan, C., Newland, H., Eigel, D., Tornillo, G., Pette, D., Brancale, A., Welzel, P. B., Seib, F. P. & Werner, C., 1 Oct 2020, In: Carbohydrate Polymers. 245, 116504.Research output: Contribution to journal › Article › peer-review
Open AccessFile13 Citations (Scopus)9 Downloads (Pure) -
Manual versus microfluidic-assisted nanoparticle manufacture: impact of silk fibroin stock on nanoparticle characteristics
Solomun, J. I., Totten, J. D., Wongpinyochit, T., Florence, A. J. & Seib, F. P., 11 May 2020, In: ACS Biomaterials Science & Engineering. 6, 5, p. 2796-2804 9 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile18 Citations (Scopus)62 Downloads (Pure) -
2019
Unraveling the impact of high-order silk structures on molecular drug binding and release behaviors
Wongpinyochit, T., Vassileiou, A. D., Gupta, S., Mushrif, S. H., Johnston, B. F. & Seib, F. P., 1 Aug 2019, In: Journal of Physical Chemistry Letters. 10, 15, p. 4278-4284 7 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile8 Citations (Scopus)8 Downloads (Pure) -
Nanomedicines for the delivery of biologics
Wahlich, J., Desai, A., Greco, F., Hill, K., Jones, A. T., Mrsny, R., Pasut, G., Perrie, Y., Seib, F. P., Seymour, L. W. & Uchegbu, I. F., 3 May 2019, In: Pharmaceutics. 11, 5, 14 p., 210.Research output: Contribution to journal › Article › peer-review
Open AccessFile25 Citations (Scopus)87 Downloads (Pure) -
PEGylation-dependent metabolic rewiring of macrophages with silk fibroin nanoparticles
Totten, J. D., Wongpinyochit, T., Carrola, J., Duarte, I. F. & Seib, F. P., 24 Apr 2019, In: ACS Applied Materials and Interfaces. 11, 16, p. 14515-14525 11 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile22 Citations (Scopus)27 Downloads (Pure) -
Microfluidic-assisted silk nanoparticle tuning
Wongpinyochit, T., Totten, J. D., Johnston, B. F. & Seib, F. P., 30 Jan 2019, In: Nanoscale Advances. 1, 2, p. 873-883 11 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile20 Citations (Scopus)23 Downloads (Pure) -
The biomedical use of silk: past, present, future
Holland, C., Numata, K., Rnjak-Kovacina, J. & Seib, F. P., 10 Jan 2019, In: Advanced Healthcare Materials. 8, 1, 26 p., 1800465.Research output: Contribution to journal › Article › peer-review
Open AccessFile405 Citations (Scopus)279 Downloads (Pure) -
2018
A review of the emerging role of silk for the treatment of the eye
Tran, S. H., Wilson, C. G. & Seib, F. P., 5 Dec 2018, In: Pharmaceutical Research. 35, 12, 16 p., 248.Research output: Contribution to journal › Article › peer-review
Open AccessFile29 Citations (Scopus)16 Downloads (Pure) -
In vivo evaluation of engineered self-assembling silk fibroin hydrogels after intracerebral injection in a rat stroke model
Gorenkova, N., Osama, I., Seib, F. P. & Carswell, H., 27 Nov 2018, (E-pub ahead of print) In: ACS Biomaterials Science & Engineering. 11 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile31 Citations (Scopus)48 Downloads (Pure) -
In vitro studies on space-conforming self-assembling silk hydrogels as a mesenchymal stem cell-support matrix suitable for minimally invasive brain application
Osama, I., Gorenkova, N., McKittrick, C. M., Wongpinyochit, T., Goudie, A., Seib, F. P. & Carswell, H. V. O., 12 Sept 2018, In: Scientific Reports. 8, 11 p., 13655.Research output: Contribution to journal › Article › peer-review
Open AccessFile23 Citations (Scopus)28 Downloads (Pure) -
Impact of the hypoxia phenotype on the uptake and efflux of nanoparticles by human breast cancer cells
Brownlee, W. J. & Seib, F. P., 17 Aug 2018, (E-pub ahead of print) In: Scientific Reports. 8, 11 p., 12318.Research output: Contribution to journal › Article › peer-review
Open AccessFile16 Citations (Scopus)25 Downloads (Pure) -
Reverse-engineered silk hydrogels for cell and drug delivery
Seib, F. P., 3 May 2018, In: Therapeutic Delivery. 9, 6, p. 469-487 19 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile30 Citations (Scopus)48 Downloads (Pure) -
Soft and flexible poly(ethylene glycol) nanotubes for local drug delivery
Newland, B., Taplan, C., Pette, D., Friedrichs, J., Steinhart, M., Wang, W., Voit, B., Seib, F. P. & Werner, C., 1 May 2018, In: Nanoscale. 10, 18, p. 8413-8421 9 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile17 Citations (Scopus)23 Downloads (Pure) -
Self-assembling hydrogels from reverse-engineered silk
Seib, P., 19 Apr 2018, Self-assembling Biomaterials: Molecular Design, Characterization and Application in Biology and Medicine. Azevedo, H. S. & da Silva, R. M. P. (eds.). 1 ed. Duxford, p. 27-47Research output: Chapter in Book/Report/Conference proceeding › Chapter
4 Citations (Scopus) -
Degradation behavior of silk nanoparticles – enzyme responsiveness
Wongpinyochit, T., Johnston, B. F. & Seib, F. P., 7 Feb 2018, (E-pub ahead of print) In: ACS Biomaterials Science & Engineering. 4, 3, p. 942-951 10 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile55 Citations (Scopus)38 Downloads (Pure) -
2017
Biocompatibility assessment of silk nanoparticles: hemocompatibility and internalization by human blood cells
Maitz, M. F., Sperling, C., Wongpinyochit, T., Herklotz, M., Werner, C. & Seib, F. P., 30 Nov 2017, In: Nanomedicine: Nanotechnology, Biology and Medicine. 13, 8, p. 2633-2642 10 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile55 Citations (Scopus)92 Downloads (Pure) -
Silk nanoparticles: proof of lysosomotropic anticancer drug delivery at single cell resolution
Totten, J. D., Wongpinyochit, T. & Seib, F. P., 16 Aug 2017, (E-pub ahead of print) In: Journal of Drug Targeting. p. 1-8 8 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile40 Citations (Scopus)60 Downloads (Pure) -
Silk hydrogels for drug and cell delivery
Seib, F. P., 12 Aug 2017, Hydrogels: Design, Synthesis & Application in Drug Delivery & Regenerative Medicine. Singh, T. R. R., Laverty, G. & Donnelly, R. (eds.). p. 208-227 20 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter
Open AccessFile85 Downloads (Pure) -
Metabolic reprogramming of macrophages exposed to silk, poly(lactic-co-glycolic acid) and silica nanoparticles
Saborano, R., Wongpinyochit, T., Totten, J. D., Johnston, B. F., Seib, P. & Duarte, I. F., 8 May 2017, (E-pub ahead of print) In: Advanced Healthcare Materials. 13 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile42 Citations (Scopus)185 Downloads (Pure) -
In vivo silk hydrogel distribution, biocompatibility and biodegradation in the brain after experimental stroke
Gorenkova, N., McKittrick, C., White, S., Ibrahim, O., Seib, F. P. & Carswell, H., 1 Apr 2017, In: Journal of Cerebral Blood Flow and Metabolism. 37, 1_suppl, p. 384-384 1 p.Research output: Contribution to journal › Conference Contribution › peer-review
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Silk nanoparticles - an emerging anticancer nanomedicine
Seib, F. P., 22 Mar 2017, In: AIMS Bioengineering. 42, 2, p. 239-258 20 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile216 Downloads (Pure) -
2016
Heparin modified polyethylene glycol microparticle aggregates for focal cancer chemotherapy
Seib, F. P., Tsurkan, M., Freudenberg, U., Kaplan, D. L. & Werner, C., 21 Oct 2016, In: ACS Biomaterials Science & Engineering. 2, 12, p. 2287-2293 7 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile22 Citations (Scopus)273 Downloads (Pure) -
Manufacture and drug delivery applications of silk nanoparticles
Wongpinyochit, T., Johnston, B. F. & Seib, P., 10 Aug 2016, In: The Journal of Visualized Experiments. 116Research output: Contribution to journal › Article › peer-review
Open AccessFile26 Citations (Scopus)104 Downloads (Pure) -
2015
PEGylated silk nanoparticles for anticancer drug delivery
Wongpinyochit, T., Uhlmann, P., Urquhart, A. J. & Seib, F. P., 9 Nov 2015, In: Biomacromolecules. 16, 11, p. 3712-3722 11 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile87 Citations (Scopus)217 Downloads (Pure) -
Focal therapy of neuroblastoma using silk films to deliver kinase and chemotherapeutic agents in vivo
Seib, F. P., Coburn, J., Konrad, I., Klebanov, N., Jones, G. T., Blackwood, B., Charest, A., Kaplan, D. L. & Chiu, B., 1 Jul 2015, In: Acta Biomaterialia. 20, p. 32-38 7 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile47 Citations (Scopus)212 Downloads (Pure) -
Tissue engineering a surrogate niche for metastatic cancer cells
Seib, F. P., Berry, J. E., Shiozawa, Y., Taichman, R. S. & Kaplan, D. L., 1 May 2015, In: Biomaterials. 51, p. 313-319 7 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile50 Citations (Scopus)309 Downloads (Pure) -
2014
A material-based platform to modulate fibronectin activity and focal adhesion assembly
Vanterpool, F. A., Cantini, M., Seib, F. P. & Salmerón-Sánchez, M., Dec 2014, In: BioResearch Open Access. 3, 6, p. 286-296 11 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile32 Citations (Scopus)59 Downloads (Pure) -
Surgery combined with controlled-release doxorubicin silk films as a treatment strategy in an orthotopic neuroblastoma mouse model
Chiu, B., Pilichowska, M., Seib, P., Charest, A. & Kaplan, DL., 12 Aug 2014, In: British Journal of Cancer. 111, 708 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile52 Citations (Scopus)57 Downloads (Pure) -
Biomaterials to direct stem cell fate
Prewitz, M., Seib, P., Pompe, T. & Werner, C., May 2014, Stem cells: from basic research to therapy. volume two: tissue homeostasis and regeneration during adulthood, applications, legislation and ethics. Calegari, F. & Waskow, C. (eds.). 1 ed. Boca Raton, Vol. 2. p. 238-270 33 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter
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Multifunctional silk-heparin biomaterials for vascular tissue engineering applications
Seib, F. P., Herklotz, M., Burke, K., Maitz, M., Werner, C. & Kaplan, D., 1 Jan 2014, In: Biomaterials. 35, 1, p. 83-91 9 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile97 Citations (Scopus)235 Downloads (Pure) -
2013
Silk for drug delivery applications: opportunities and challenges
Seib, F. P. & Kaplan, D., Oct 2013, In: Israel Journal of Chemistry. 53, 9-10, p. 756-766 11 p.Research output: Contribution to journal › Article › peer-review
28 Citations (Scopus) -
Surgical resection combined with application of doxorubicin-loaded sustained release silk film as a treatment strategy in an orthotopic xenograft neuroblastoma mouse model
Chiu, B., Coburn, J., Seib, F. P., Charest, A. & Kaplan, D. L., 1 Sept 2013, In: Journal of the American College of Surgeons . 217, 3Research output: Contribution to journal › Article › peer-review
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Self-assembling doxorubicin silk hydrogels for the focal treatment of primary breast cancer
Seib, F. P., Pritchard, E. M. & Kaplan, D. L., 7 Jan 2013, In: Advanced Functional Materials. 23, 1, p. 58–65 8 p.Research output: Contribution to journal › Article › peer-review
121 Citations (Scopus) -
pH-dependent anticancer drug release from silk nanoparticles
Seib, F. P., Jones, G., Rnjak-Kovacina, J., Lin, Y. & Kaplan, D. L., 2013, In: Advanced Healthcare Materials. 6 p.Research output: Contribution to journal › Article › peer-review
174 Citations (Scopus) -
Tightly anchored tissue-mimetic matrices as instructive stem cell microenvironments
Prewitz, M., Seib, F. P., von Bonin, M., Friedrichs, J., Stißel, A., Niehage, C., Müller, K., Anastassiadis, K., Waskow, C., Hoflack, B., Bornhäuser, M. & Werner, C., 2013, In: Nature Methods . 10, 8, p. 788–794 7 p.Research output: Contribution to journal › Article › peer-review
164 Citations (Scopus) -
2012
Doxorubicin-loaded silk films: drug-silk interactions and in vivo performance in human orthotopic breast cancer
Seib, F. P. & Kaplan, D. L., Nov 2012, In: Biomaterials. 33, 33, p. 8442-8450 9 p.Research output: Contribution to journal › Article › peer-review
89 Citations (Scopus) -
Polymeric biomaterials for stem cell bioengineering
Prewitz, M., Seib, F. P., Pompe, T. & Werner, C., 14 Sept 2012, In: Macromolecular Rapid Communications. 33, 17, p. 1420-1431 12 p.Research output: Contribution to journal › Article › peer-review
36 Citations (Scopus)