My work as a bioinformatician has primarily been applied to plant pathogens, and covered multiple kingdoms of life including viruses, bacteria, and Eukaryotes like nematodes, and occasionally plants. One major project focused on metabarcoding of environmental DNA for oomycetes with implications for tree health, developing the THAPBI PICT pipeline. I am currently working on pyANI-plus for whole-genome classification of microbes using Average Nucleotide Identity and similar methods. These projects and most of my other software work is released as Open Source. I have for many years contributed to the Biopython Project and the Open Bioinformatics Foundation as a board member, and am the current president.