Projects per year
Personal profile
Personal Statement
I am a Chancellors Fellow within the Department of Biomedical Engineering. My research interests center on mechnicsms to control cell function/fate using mechanical stimulation and biomaterials. The goal of these investigations largely relate to regenerative medicine and tissue repair through the development of new implantable cellular and acellular biomaterials.
Since 2012 I have been involved with a multidisciplinary collaboration using nano-amplitude vibration to stimulate bone formation from adult stem cells in a process dubbed 'nanokicking'. This technology is now being translated towards clinic to produce an osteogenic cell therapy for orthopaedic repair. I have also been involved in the pre-clinical translation of implantable bioactive polymers for growth factor delivery ('HealiOst'). Previously, I was awarded a Royal Society of Edinburgh Enterprise Fellowship and have a keen interest in the clinical/commercial translation of cell engineering technologies.
Keywords
- Tissue engineering
- stem cells
- mechanobiology
- vibration
- clinical translation
- bioreactors
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Mechanobiology-based medicine / Mechanomeds
Zagnoni, M. (Principal Investigator) & Childs, P. (Co-investigator)
EPSRC (Engineering and Physical Sciences Research Council)
1/10/23 → 30/09/28
Project: Research
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BRAINS: BRAINS Strathclyde Centre for Doctoral Training
MacKenzie, L. (Principal Investigator), Childs, P. (Principal Investigator), Witte, K. (Principal Investigator), Jimenez, M. (Principal Investigator), Chow, S. (Principal Investigator), Fu, Y. (Principal Investigator), Gomez-Roman, N. (Principal Investigator), Fazio, M. (Principal Investigator) & Reid, A. B. (Principal Investigator)
1/05/23 → …
Project: Internally funded project
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Developing and investigating a nanovibration intervention for the prevention/reversal of bone loss following spinal cord injury
Williams, J. A., Campsie, P., Gibson, R., Johnson-Love, O., Werner, A., Sprott, M., Meechan, R., Huesa, C., Windmill, J. F. C., Purcell, M., Coupaud, S., Dalby, M. J., Childs, P., Riddell, J. S. & Reid, S., 9 Jul 2024, In: ACS Nano. 18, 27, p. 17630-17641 12 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile15 Downloads (Pure) -
Engineered surfaces that promote capture of latent proteins to facilitate integrin-mediated mechanical activation of growth factors
Dhawan, U., Williams, J. A., Windmill, J. F. C., Childs, P., Gonzalez-Garcia, C., Dalby, M. J. & Salmeron-Sanchez, M., 6 Jun 2024, In: Advanced Materials. 36, 23, 15 p., 2310789.Research output: Contribution to journal › Article › peer-review
Open AccessFile49 Downloads (Pure)
Datasets
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Data for: "Design, construction and characterisation of a novel nanovibrational bioreactor and cultureware for osteogenesis"
Campsie, P. (Creator), Childs, P. (Creator), Robertson, S. (Creator), Cameron, K. (Creator), Hough, J. (Creator), Salmerón-Sánchez, M. (Creator), Tsimbouri, P. M. (Creator), Vichare, P. (Creator), Dalby, M. J. (Creator) & Reid, S. (Creator), University of Strathclyde, 19 Aug 2020
DOI: 10.15129/6aaa2114-2ce4-4e63-a0a4-af34ad3f6324
Dataset
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Data for "Developing and Investigating a Nanovibration Intervention for the Prevention/Reversal of Bone Loss Following Spinal Cord Injury"
Williams, J. (Creator), Campsie, P. (Contributor), Gibson, R. (Contributor), Johnson-Love, O. (Contributor), Huesa, C. (Contributor), Windmill, J. (Contributor), Purcell, M. (Creator), Coupaud, S. (Contributor), Dalby, M. J. (Contributor), Childs, P. (Contributor), Riddell, J. S. (Creator) & Reid, S. (Contributor), University of Strathclyde, 16 Jul 2024
DOI: 10.15129/0b2d2d47-f4c9-40a6-a2ad-72565a740e37
Dataset
Activities
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High throughput mechanical phenotyping of nano vibrated mesenchymal stem cells using real time deformability cytometry
Pereira Sousa, R. P. (Speaker), Jimenez, M. (Speaker), Reid, S. (Speaker) & Childs, P. (Speaker)
10 Jun 2024Activity: Talk or presentation types › Oral presentation
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LifEtime CDT Dragon's Den
Childs, P. (Participant)
May 2023 → Sept 2023Activity: Participating in or organising an event types › Participation in workshop, seminar, course