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I am a Chancellors Fellow within the Department of Biomedical Engineering. My research interests center on mechnicsms to control cell function/fate using mechanical stimulation and biomaterials. The goal of these investigations largely relate to regenerative medicine and tissue repair through the development of new implantable cellular and acellular biomaterials.
Since 2012 I have been involved with a multidisciplinary collaboration using nano-amplitude vibration to stimulate bone formation from adult stem cells in a process dubbed 'nanokicking'. This technology is now being translated towards clinic to produce an osteogenic cell therapy for orthopaedic repair. I have also been involved in the pre-clinical translation of implantable bioactive polymers for growth factor delivery ('HealiOst'). Previously, I was awarded a Royal Society of Edinburgh Enterprise Fellowship and have a keen interest in the clinical/commercial translation of cell engineering technologies.
- Tissue engineering
- stem cells
- clinical translation
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- 2 Active
31/03/21 → 30/03/22
1/05/20 → 30/04/25
The use of nanovibration to discover specific and potent bioactive metabolites that stimulate osteogenic differentiation in mesenchymal stem cellsHodgkinson, T., Monica Tsimbouri, P., Llopis-Hernandez, V., Campsie, P., Scurr, D., Childs, P. G., Phillips, D., Donnelly, S., Wells, J., Salmerón-Sánchez, M., Burgess, K. E. V., Alexander, M., Vassalli, M., Oreffo, R., Reid, S., France, D. J. & Dalby, M. J., 26 Feb 2021, In: Science Advances. 7, 9, 17 p., eabb7921.
Research output: Contribution to journal › Article › peer-reviewOpen AccessFile1 Downloads (Pure)
Childs, P. G., Reid, S., Salmeron-Sanchez, M. & Dalby, M. J., 17 Sep 2020, In: The Biochemical journal. 477, 17, p. 3349-3366 18 p.
Research output: Contribution to journal › Article › peer-reviewOpen AccessFile
Data for: "Design, construction and characterisation of a novel nanovibrational bioreactor and cultureware for osteogenesis"
Campsie, P. (Creator), Childs, P. (Creator), Robertson, S. (Creator), Cameron, K. (Creator), Hough, J. (Creator), Salmerón-Sánchez, M. (Creator), Tsimbouri, P. M. (Creator), Vichare, P. (Creator), Dalby, M. J. (Creator) & Reid, S. (Creator), University of Strathclyde, 19 Aug 2020
- 1 Oral presentation