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Personal profile

Research Interests

My research background is in molecular and population genetics, which are the fields of science that underpin the analysis, statistical interpretation and evaluation of forensic DNA evidence. I have therefore developed forensic genetics research by applying my experience to questions of a forensic nature. I am interested in the development of nucleic acid (DNA and RNA) assays to determine the source, type, age and time of deposition of forensic samples, such as single or mixed body fluid stains and touch DNA. Current research in forensic genetics includes development of DNA methylation models to accurately determine the age of the donor of unknown body fluid samples, RNA degradation assays to determine the time of deposition of body fluid stains and the use of novel DNA profiling methods across different global populations. 

Teaching Interests

I teach a variety of topics in forensic science, principally in the area of forensic biology, across first to final year BSc/MChem Forensic and Analytical Chemistry undergraduates, and to MSc Forensic Science postgraduate students. I lecture on a range of trace evidence types, including fibres, hairs, pollen, glass and paint, and cover the search and recovery of trace evidence as well as the evaluation of its significance using frequency databases. I also cover methods for the analysis of trace evidence, including a variety of specialised microscopy techniques and colour/dye analyses. I deliver advanced modules on DNA evidence, covering theoretical and practical aspects of DNA profiling, the interpretation and population genetic analysis of DNA profiling data, and methods for dealing with DNA mixtures, which result in profiles that include contributions from more than one individual. I teach biological evidence evaluation, including the evaluation of sexual offence and DNA evidence, incorporating the calculation of random match probabilities and likelihood ratios, and the use of the Bayesian framework for assessing the significance of evidence. I also coordinate the major crime scene exercise, which runs as part of the MSc Forensic Science, during which students investigate simulated outdoor crime scenes, develop forensic strategy, undertake all laboratory analysis and evidence interpretation, then present their evidence in court in a joint exercise with the University of Strathclyde Law School.

Fingerprint Fingerprint is based on mining the text of the person's scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

Drosophila melanogaster Medicine & Life Sciences
Drosophila Medicine & Life Sciences
Genes Chemical Compounds
Polymorphism Chemical Compounds
Genome Medicine & Life Sciences
Codon Medicine & Life Sciences
Adalia bipunctata Agriculture & Biology
Chromosomes Chemical Compounds

Research Output 2000 2017

A multi-tissue age prediction model based on DNA methylation analysis

Alsaleh, H., McCallum, N. A., Halligan, D. L. & Haddrill, P. R., 31 Dec 2017, In : Forensic Science International: Genetics Supplement Series. 6, p. e62-e64 3 p.

Research output: Contribution to journalArticle

Open Access
File
DNA Methylation
Genetic Markers
Saliva
Somatotypes
Cheek
2 Citations
Open Access
File
RNA Stability
Crime
MicroRNAs
RNA
Messenger RNA