Paul Hoskisson - Network - University of Strathclyde

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Phone01415482819
Emailpaul.hoskissonstrath.acuk

United Kingdom

Accepting PhD Students

PhD projects

Functional characterisation of cell wall deacetylases in Corynebacterium diphtheriae<br/><br/>Modification of the bacterial cell wall is one of the most fundamental processes that bacteria use to adapt and to survive in changing environmental conditions. The ability to modify the bacterial cell wall, which is a essential component of the bacterial cell envelope, through modification and decoration is a key adaptation that bacteria use to avoid host defences (such as hydrolytic enzymes) and enhance survival in host cells. These modifications can be highly complicated such as the covalent and non-covalent attachment of proteins, lipids and polysaccharides. Important human pathogens such as Corynebacterium and Mycobacterium have taken cell wall decoration to extraordinary levels with the attachment of highly specialised mycolic acids, arabinomannan, glycolipids and proteins, which have been relatively well studied in these organisms (sometimes referred to as the Mycolata). Some of these components, such as the mycolic acids are vital components and are essential for pathogenicity and in some cases viability. Other modifications of cell wall polymers such as N-deacetylations have received relatively little attention. It is these that will be the focus of this project, where will investigate the role of cell wall deacetylases in the growth and pathogenicity of Corynebacterium diphtheriae. We will also investigate the enzymology of the C. diphtheriae enzyme to elucidate its substrate and co-factor specificity.

Faculty Of Science

University Of Strathclyde

Organisational unit: Faculty

157 shared research output

University Of Strathclyde

Organisational unit: University

157 shared research output

Physics

Faculty Of Science

Organisational unit: Department

29 shared research output

Measurement, Digital and Enabling Technologies

Organisational unit: Interdisciplinary Research Theme

21 shared research output

Health and Wellbeing

Organisational unit: Interdisciplinary Research Theme

17 shared research output

Faculty Of Engineering

University Of Strathclyde

Organisational unit: Faculty

13 shared research output

Biomedical Engineering

Faculty Of Engineering

Organisational unit: Department

11 shared research output

Pure And Applied Chemistry

Faculty Of Science

Organisational unit: Department

10 shared research output

Research Pooling

University Of Strathclyde

Organisational unit: Research

7 shared research output

Doctoral Training Centres

University Of Strathclyde

Organisational unit: Research

7 shared research output

SUPA

Research Pooling

Organisational unit: Research

7 shared research output

Medical Devices and Health Technologies

Doctoral Training Centres

Organisational unit: Research

6 shared research output

Electronic And Electrical Engineering

Faculty Of Engineering

Organisational unit: Department

4 shared research output

Civil And Environmental Engineering

Faculty Of Engineering

Organisational unit: Department

3 shared research output

Psychological Sciences And Health

Faculty Of Humanities And Social Sciences

Organisational unit: School

2 shared research output

Mathematics And Statistics

Faculty Of Science

Organisational unit: Department

2 shared research output

Faculty Of Humanities And Social Sciences

University Of Strathclyde

Organisational unit: Faculty

2 shared research output

GlaxoSmithKline

Doctoral Training Centres

Organisational unit: Research

1 shared research output

University of Strathclyde

External organisation: UK Educational Institution

5 shared research output

University of Strathclyde

External organisation: Unknown

4 shared research output

Glasgow Royal Infirmary

External organisation: Unknown

4 shared research output

Northumbria University

External organisation: UK Educational Institution

4 shared research output

University of Glasgow

External organisation: UK Educational Institution

4 shared research output

University of Newcastle

External organisation: UK Educational Institution

3 shared research output

University of Glasgow

External organisation: Unknown

3 shared research output

University of Dundee

External organisation: UK Educational Institution

3 shared research output

Kasetsart University

External organisation: Unknown

2 shared research output

Leiden University

External organisation: Unknown

2 shared research output

University of Wisconsin-Madison

External organisation: Unknown

2 shared research output

STFC Rutherford Appleton Lab

External organisation: Not specified

2 shared research output

Kasetsart University

External organisation: Unknown

2 shared research output

SIPBS, Strathclyde Inst Pharm & Biomed Sci

External organisation: Not specified

2 shared research output

HERIOT-WATT UNIVERSITY

External organisation: Unknown

2 shared research output

Green Chemistry Centre of Excellence, University of York, Department of Chemistry, University of York, Heslington, York YO10 5DD, U.K.

External organisation: Unknown

2 shared research output

STFC Rutherford Appleton Laboratory

External organisation: Unknown

2 shared research output

University of East Anglia

External organisation: UK Educational Institution

2 shared research output

Friedrich-Alexander University Erlangen

External organisation: Unknown

2 shared research output

Heriot-Watt University

External organisation: Unknown

2 shared research output

Acibadem Mehmet Ali Aydinlar University

External organisation: Overseas other (non-European)

2 shared research output

Royal Alexandra Hospital

External organisation: Unknown

2 shared research output

LifeScan

External organisation: Unknown

2 shared research output

Free University of Brussels

External organisation: EU Other

2 shared research output

The Roslin Institute and Royal (Dick) School of Veterinary Studies

External organisation: Unknown

1 shared research output

University of Leeds

External organisation: Unknown

1 shared research output

University of California

External organisation: Unknown

1 shared research output

University of Ljubljana

External organisation: EU Other

1 shared research output

Health Protection Scotland, Glasgow and Royal Alexandra Hospital

External organisation: Unknown

1 shared research output

Edge Hill University

External organisation: Unknown

1 shared research output

Acies Bio D.O.O.

External organisation: Unknown

1 shared research output

STFC Rutherford Appleton Laboratory

External organisation: Unknown

1 shared research output

Leiden University

External organisation: Unknown

1 shared research output

GlaxoSmithKline, Medicines Research Centre, Gunnels Wood Road, Stevenage, Hertfordshire SG1 2NY, UK

External organisation: Corporate

1 shared research output

Ankara Yildirim Beyazit University

External organisation: Overseas other (non-European)

1 shared research output

University of Mosul

External organisation: Unknown

1 shared research output

Lehrstuhl für Mikrobiologie, Friedrich-Alexander-Universität Erlangen-Nürnberg, Germany.

External organisation: Unknown

1 shared research output

Microbial Biotechnology, Institute of Biology, Leiden University, Rapenburg, The Netherlands

External organisation: Unknown

1 shared research output

IInstitute of Marine Affairs

External organisation: Unknown

1 shared research output

Colorifix Ltd, Norwich Research Park, Norwich, UK

External organisation: Unknown

1 shared research output

Kasetsart University (OmiKU), Omics Center for Agriculture, Bioresources, Food and Health, Bangkok, Thailand, GRID: grid.9723.f, ISNI: 0000 0001 0944 049X

External organisation: Unknown

1 shared research output

Humboldt-Universität zu Berlin

External organisation: Unknown

1 shared research output

Department of Molecular Microbiology, John Innes Centre, Norwich Research Park, Norwich NR4 7UH, UK

External organisation: Unknown

1 shared research output

Rio de Janeiro State University

External organisation: Unknown

1 shared research output

Acies Bio Ltd

External organisation: Not specified

1 shared research output

University of Illinois at Urbana-Champaign

External organisation: Unknown

1 shared research output

Newcastle University

External organisation: Unknown

1 shared research output

University of Aberdeen

External organisation: Unknown

1 shared research output

University of Illinois at Urbana-Champaign

External organisation: Unknown

1 shared research output

Laboratorio de Microbiología Molecular y Biotecnología Ambiental, Departamento de Química & Centro de Biotecnología Daniel Alkalay Lowitt, Universidad Técnica Federico Santa María, Valparaíso 2340000, Chile

External organisation: Unknown

1 shared research output

University of Birmingham

External organisation: Unknown

1 shared research output

Glasgow University

External organisation: Unknown

1 shared research output

Nottingham Trent University

External organisation: Unknown

1 shared research output

University of Glasgow

External organisation: UK Educational Institution

1 shared research output

Microbiology Department, Royal Infirmary of Edinburgh, 51 Little France Cresent, Old Dalkeith Road, Edinburgh EH16 4SA, UK.

External organisation: Unknown

1 shared research output

Novo mesto

External organisation: Unknown

1 shared research output

University of Glasgow

External organisation: Unknown

1 shared research output

University of East Anglia

External organisation: Unknown

1 shared research output

Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, United Kingdom

External organisation: Unknown

1 shared research output

Faculty of Biological Sciences, University of Leeds, Leeds, LS2 9JT, UK; Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds, LS2 9JT, UK

External organisation: Unknown

1 shared research output

University of Birmingham

External organisation: Unknown

1 shared research output

School of Chemistry, Centre for Biomolecular Sciences, University of Nottingham

External organisation: Unknown

1 shared research output

Leiden University

External organisation: Unknown

1 shared research output

Institute of Microbiology and Infection, College of Medical and Dental Science, University of Birmingham, Birmingham, United Kingdom

External organisation: Unknown

1 shared research output

Bioinformatics Resource Facility, Center for Biotechnology (CeBiTec), Bielefeld University, Germany.

External organisation: Unknown

1 shared research output

Universidad Nacional Autónoma de México, Centro de Ciencias Matemáticas, en Morelia, Michoacán, Mexico

External organisation: Unknown

1 shared research output

John Innes Ctr

External organisation: Not specified

1 shared research output

Northumbria University

External organisation: Unknown

1 shared research output

University of Glasgow

External organisation: Unknown

1 shared research output

University of Leeds

External organisation: UK Educational Institution

1 shared research output

College of Life Sciences, University of Dundee, Dundee DD1 5EH, UK.

External organisation: Unknown

1 shared research output

Diamond House, Diamond Light Source

External organisation: Not specified

1 shared research output

SUPA

External organisation: Unknown

1 shared research output

Newcastle University

External organisation: Unknown

1 shared research output

Georgia Institute of Technology

External organisation: Overseas other (non-European)

1 shared research output

Department of Chemistry, Durham University, South Road, Durham DH1 3LE, UK

External organisation: Unknown

1 shared research output

International Microbiome Centre, University of Calgary, Calgary, Canada

External organisation: Unknown

1 shared research output

Bangor University

External organisation: UK Educational Institution

1 shared research output

Leeds University

External organisation: Unknown

1 shared research output

GlaxoSmithKline

External organisation: Unknown

1 shared research output

Department of Critical Care Medicine, Cumming School of Medicine, University of Calgary, Calgary, Canada

External organisation: Unknown

1 shared research output

Isomerase Therapeutics Ltd

External organisation: Unknown

1 shared research output

Helsinki Institute of Information Technology, Department of Mathematics and Statistics, University of Helsinki, Helsinki, Finland

External organisation: Unknown

1 shared research output

Aberdeen Royal Infirmary

External organisation: Unknown

1 shared research output

Universidad Autónoma de Baja California

External organisation: Academic

1 shared research output

University of Queensland

External organisation: Unknown

1 shared research output

Queen's University Belfast

External organisation: Unknown

1 shared research output

Newcastle University

External organisation: Unknown

1 shared research output

University of Glasgow

External organisation: Unknown

1 shared research output

Lawrence Berkeley National Laboratory, Environmental Genomics and Systems Biology Division, Berkeley, CA 94720, USA; US Department of Energy Joint Genome Institute, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA

External organisation: Unknown

1 shared research output

Mosul University

External organisation: Unknown

1 shared research output

University of York

External organisation: Unknown

1 shared research output

Department of Insect Symbiosis, Max Planck Institute for Chemical Ecology, Hans-Knöll-Straße 8, 07745 Jena, Germany

External organisation: Unknown

1 shared research output

Ikerbasque, Basque Foundation for Research

External organisation: Unknown

1 shared research output

Calvin, Phoebe, and Joan Snyder Institute for Chronic Diseases, Cumming School of Medicine, University of Calgary, Calgary, Canada

External organisation: Unknown

1 shared research output

Kasetsart University, Department of Genetics, Faculty of Sciences, Bangkok, Thailand, GRID: grid.9723.f, ISNI: 0000 0001 0944 049X

External organisation: Unknown

1 shared research output

School of Biological Sciences, University of East Anglia, Norwich Research Park, Norwich, NR4 7TJ, UK

External organisation: Unknown

1 shared research output

University of Glasgow

External organisation: Unknown

1 shared research output

Department of Conservation of Natural Resources, Neiker, Basque Institute for Agricultural Research

External organisation: Academic

1 shared research output

Université Libre de Bruxelles

External organisation: External collaborations

1 shared research output

Haverford College, Department of Chemistry, USA

External organisation: Unknown

1 shared research output

Edgehill University

External organisation: Unknown

1 shared research output

University of York

External organisation: UK Educational Institution

1 shared research output

Laboratoire de Dynamique des Interactions Membranaires Normales et Pathologiques, Université de Montpellier II

External organisation: Academic

1 shared research output

Edge Hill University

External organisation: Unknown

1 shared research output

School of Electronic and Electrical Engineering, University of Leeds

External organisation: Unknown

1 shared research output

University of Glasgow

External organisation: Not specified

1 shared research output

Strathclyde Institute of Pharmacy and Biomedical Sciences

External organisation: Unknown

1 shared research output

The James Hutton Institute, Invergowrie, Dundee, UK.

External organisation: Unknown

1 shared research output

Indian Institute of Technology Bombay

External organisation: Non-EU Others

1 shared research output

Chester Zoo

External organisation: Unknown

1 shared research output

Leibniz Institute DSMZ - German Collection of Microorganisms and Cell Cultures GmbH Inhoffenstraße 7B, 38124 Braunschweig, Germany

External organisation: Unknown

1 shared research output

Division of Bioinformatics and Data Management for Research, Research Group and Research Network Division, Research Department, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand

External organisation: Unknown

1 shared research output

University of Northumbria

External organisation: UK Educational Institution

1 shared research output

Host-Microbe Interactomics Group, Wageningen University, 6708 WD Wageningen, The Netherlands

External organisation: Unknown

1 shared research output

University of Glasgow

External organisation: Unknown

1 shared research output

Eskişehir Osmangazi Üniversitesi

External organisation: Overseas other (non-European)

1 shared research output

Swansea University Institute of Life Science, College of Medicine, Swansea, Wales, UK

External organisation: Unknown

1 shared research output

Institut Pasteur, Paris

External organisation: EU Government Bodies

1 shared research output

School of Biological and Behavioral Sciences, Queen Mary University of London, Mile End Road, London, E1 4NS, UK

External organisation: Unknown

1 shared research output

The Scottish Association for Marine Science

External organisation: UK Educational Institution

1 shared research output

Newcastle University

External organisation: Unknown

1 shared research output

Instituto de Agricultura Sostenible, Consejo Superior de Investigaciones Científicas (CSIC)

External organisation: Unknown

1 shared research output

John Innes Centre

External organisation: Unknown

1 shared research output

Leiden University

External organisation: Unknown

1 shared research output

Institute for Microbiology and Wine Research, Johannes Gutenberg-University Mainz

External organisation: EU Other

1 shared research output