Projects per year
Personal profile
Personal Statement
Laboratory webpage is here http://paulhoskisson.weebly.com
Research in my group is focussed on the synthesis of antibiotics and the evolution of bacterial pathogens, using a range of techniques from molecular biology and biochemistry through to mathematical modelling and image analysis. The bacterial genus Streptomyces is the main focus of work in my Research Group due to its industrial importance, being responsible for producing around two thirds of all commercially important antibiotics as well as numerous anti-fungal, anti-helminthic and anti-cancer drugs.
We also have an interest in evolution of metabolism, evolution of bacterial pathogens, genomics of actinobacteria and the exploitation of amphibian proteins for biotechnology.
We use a range of techniques to study the biology of actinobacteria including molecular genetics, protein biochemistry, genomics, microscopy, physiology, advanced spectroscopy, mathematical modeling and bioinformatics.
I was elected as a member of the Royal Society of Edinburgh Young Academy of Scotland in 2014 and a Fellow of the Royal Society of Biology (FRSB) in 2016.
I am a member of the Microbiology Society, the American Society of Microbiology, the Biochemical Society, The Royal Society of Biology and British Herpetological Society.
I am a managing editor for Antonie van Leeuwenhoek International Journal of Microbiology, and sit on the editorial board for Microbial Genomics, Frontiers in Antimicrobials, resistance and chemotherapy, Frontiers in Microbial Physiology and Metabolism, Frontiers in Synthetic Biology and Metabolism and Nature Scientific Data and Nature Scientific Reports.I am a former Editor in Chief of Microbiology Today.
I am a Fellow of the Higher Education Academy.
I am interested in the use of Social media for communication of science and you can follow on Twitter @paulhoskisson
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Keywords
- Microbiology; biochemistry; molecular biology; Streptomyces; Corynebacterium
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Collaborations and top research areas from the last five years
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Engineering Streptomyces bacteria for the sustainable manufacture of antibiotics
Hoskisson, P. (Principal Investigator)
BBSRC (Biotech & Biological Sciences Research Council)
14/02/24 → 13/02/26
Project: Research
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Taming of the Streptomycete: Understanding the rules of domestication in antibiotic-producing bacteria
Hoskisson, P. (Principal Investigator)
BBSRC (Biotech & Biological Sciences Research Council)
1/12/23 → 30/11/26
Project: Research
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Quantifying the fractal complexity of nutrient transport channels in Escherichia coli biofilms under varying cell shape and growth environment
Bottura, B., Rooney, L., Feeney, M., Hoskisson, P. A. & McConnell, G., 5 Nov 2024, In: Microbiology. 170, 11, 11 p., 001511.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Downloads (Pure) -
Gram-scale enzymatic synthesis of 2′-deoxyribonucleoside analogues using nucleoside transglycosylase-2
Salihovic, A., Ascham, A., Taladriz-Sender, A., Bryson, S., Withers, J. M., Mckean, I. J. W., Hoskisson, P. A., Grogan, G. & Burley, G. A., 7 Oct 2024, In: Chemical Science. 15, 37, p. 15399-15407 9 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)7 Downloads (Pure)
Datasets
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Data for "Genomic analysis of endemic clones of toxigenic and non-toxigenic Corynebacterium diphtheriae in Belarus during and after the major epidemic in 1990s"
Grosse-Kock, S. (Creator), Kolodkina, V. (Creator), Schwalbe, E. C. (Creator), Blom, J. (Creator), Burkovski, A. (Creator), Hoskisson, P. A. (Creator), Brisse, S. (Creator), Smith, D. (Creator), Sutcliffe, I. C. (Creator), Titov, L. (Creator) & Sangal, V. (Contributor), figshare, 14 Jun 2023
DOI: 10.6084/m9.figshare.c.3929158.v1
Dataset
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Data for "Adherence and invasive properties of Corynebacterium diphtheriae strains correlates with the predicted membrane-associated and secreted proteome"
Sangal, V. (Contributor), Blom, J. (Creator), Sutcliffe, I. C. (Creator), von Hunolstein, C. (Contributor), Burkovski, A. (Creator) & Hoskisson, P. A. (Creator), figshare, 14 Jun 2023
DOI: 10.6084/m9.figshare.c.3646040.v1
Dataset
Prizes
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Appointed as a core member of BBSRC Committee D - Molecules, cells and industrial biotechnology
Hoskisson, P. (Recipient), 1 May 2020
Prize: Appointment
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Activities
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BBSRC (Biotech & Biological Sciences Research Council) (External organisation)
Hoskisson, P. (Advisor)
23 Sept 2024Activity: Membership types › Membership of committee
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BBSRC (Biotech & Biological Sciences Research Council) (External organisation)
Hoskisson, P. (Advisor)
21 Feb 2024Activity: Membership types › Membership of committee