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Personal profile

Personal Statement

Studying how the human body works helps us to understand the many processes that maintain health and find better treatment for diseases. Through excellent research and teaching we can make a difference to future populations by improving our knowledge of health and disease.

Cardiovascular disease is particularly interesting; Heart and vascular health is fundamental to healthy living but nonetheless remains the greatest disease burden in the developed western world and remains a challenging area in biology.

Heart attack, stroke and peripheral vascular disease are all driven by changes in vascular structure and function. The study of blood vessels and blood vessel cell biology in health and disease are central my research groups activity.

Working with colleagues within SIPBS (Biology, Pharmacology, Formulation, Drug Delivery, Pharmacy Practice) and within the wider research community within the University of Strathclyde (Chemistry, Bio-Engineering) ensures our collaborative research work is exciting and truly focusing on real clinical needs.  

Research Interests

Dr Paul Coats is an active researcher within cardiovascular research in SIPBS. His research focus is vascular physiology (health) and pathophysiology (disease). The studies of both large and small blood vessels are core to the research directed by Dr Paul Coats.

Specific research work:

  • Role of reactive oxygen species in modulating acute vascular contractile responses in the microcirculation
  • Effect of chronic ischaemic vascular disease on blood vessel structure and function
  • Identifying mechanisms of vascular restenosis in response to stent insertion or balloon angioplasty
  • Mechanisms underlying arteriovenous fistula (AVF) stenosis that occurs in people undergoing renal dialysis 

Expertise & Capabilities

  • Vascular organ bath pharmacology
  • Pressure Myography
  • Primary cell culture
  • Vascular Imaging
  • Novel drug delivery 

Industrial Relevance

Working in collaboration with colleagues within SIPBS, Chemistry and Bio-Engineering Dpts drug design and delivery research with our well established cell, organ culture and in-vivo models has a track record of attracting industrial support/ collaboration. 

Fingerprint Fingerprint is based on mining the text of the person's scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

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Projects 2004 2021

Research Output 1999 2017

  • 335 Citations
  • 21 Article
  • 5 Meeting abstract
  • 1 Literature review

Mitochondria has a role in regulating hypoxic-dependent cell proliferation in pulmonary cells and vascular remodelling

Coats, P., Plevin, R. & Burzangi, A. 30 Apr 2017 In : Heart . 103, Suppl 2, p. A6-A7 2 p.

Research output: Contribution to journalMeeting abstract

Open Access
Mitochondria
Cell Proliferation
Lung
Mitochondrial Dynamics
Messenger RNA
Open Access
MicroRNAs
Vascular Smooth Muscle
Smooth Muscle Myocytes
Cell Movement
Atherosclerosis

Thesis

Mitochondrial regulation of vascular smooth muscle cell proliferation and migration in atherogenesis and re-stenosis

Author: Al Sulti, Z. S. R., 1 Oct 2016

Supervisor: Coats, P. (Supervisor) & McCarron, J. (Supervisor)

Student thesis: Doctoral Thesis