Projects per year
Personal profile
Personal Statement
Principle research interests lie in investigating metabolic changes throughout human life course with a focus on the dynamics of energy metabolism alongside biomarker detection. Currently developing a targeted research theme that incorporates pregnancy, frailty and ageing related clinical projects alongside novel analytical approaches that enable the targeting and quantification of pathways critical to biochemical energy production.
Portfolio of clinical research has covered a broad range of concepts including:
- Population level analysis of frailty metabolism
- Early diagnostic and theranostic biomarker detection
- Energy metabolism across the placenta
- Ageing effects the biological and metabolic basis of cancer
This work has also been complemented by development of statistical tools to understand how metabolite data can be automatically linked to biochemical pathways, helping to inform genomic studies and ultimately to develop models linking metabolic data and exposures to epidemiological studies.
Expertise & Capabilities
Lab has broad experience in
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Projects
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STRAthclyde Diversity in Data LinkagE (STRADDLE) Doctoral Training Centre
Barry, S., Kavanagh, K., Megiddo, I., Murray, P. & Rattray, N.
1/10/19 → 31/03/23
Project: Research - Studentship
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Exploring the role of the gut microbiome and its interaction with food components in patients with Crohn’s disease - an integrated systems biology approach
1/03/21 → 1/03/24
Project: Internally funded project
Research Output
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An ENT2-dependent, cell-penetrating, and DNA-damaging lupus autoantibody crosses the blood-brain barrier to target brain tumors
Rattray, Z., Deng, G., Zhang, S., Shirali, A., May, C., Liu, J., Zou, P., Cuffari, B., Rattray, N., Johnson, C., Dubljevic, V., Campbell, J., Huttner, A., Baehring, J., Zhou, J. & Hansen, J., 4 Aug 2020, In : Neuro-Oncology Advances. 2, Supplement 2, p. ii13-ii13 1 p.Research output: Contribution to journal › Meeting abstract
Open Access -
Sex differences in colon cancer metabolism reveal a novel subphenotype
Cai, Y., Rattray, N. J. W., Zhang, Q., Mironova, V., Santos-Neto, A., Hsu, K-S., Rattray, Z., Cross, J. R., Zhang, Y., Paty, P. B., Khan, S. A. & Johnson, C. H., 17 Mar 2020, In : Scientific Reports. 10, 13 p., 4905.Research output: Contribution to journal › Article
Open AccessFile1 Citation (Scopus)2 Downloads (Pure)
Activities
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Deadlier colon cancer develops differently in women and men
Zahra Rattray (Recipient) & Nicholas Rattray (Recipient)
17 Mar 2020Activity: Other activity types › Types of Public engagement and outreach - Media article or participation
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MSc Thesis Examination
Nicholas Rattray (Examiner)
28 Jan 2020Activity: Examination types › Examination