Projects per year
Personal profile
Personal Statement
Principle research interests lie in investigating metabolic changes throughout human life course with a focus on the dynamics of energy metabolism alongside biomarker detection. Currently developing a targeted research theme that incorporates pregnancy, frailty and ageing related clinical projects alongside novel analytical approaches that enable the targeting and quantification of pathways critical to biochemical energy production.
Portfolio of clinical research has covered a broad range of concepts including:
- Population level analysis of frailty metabolism
- Early diagnostic and theranostic biomarker detection
- Energy metabolism across the placenta
- Ageing effects the biological and metabolic basis of cancer
This work has also been complemented by development of statistical tools to understand how metabolite data can be automatically linked to biochemical pathways, helping to inform genomic studies and ultimately to develop models linking metabolic data and exposures to epidemiological studies.
Expertise & Capabilities
Lab has broad experience in
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Projects
- 3 Active
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The impact of KPNA2 overexpression on breast cancer cellular phenotype (RSE Reboot)
8/04/21 → 7/10/21
Project: Research
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Exploring the role of the gut microbiome and its interaction with food components in patients with Crohn’s disease - an integrated systems biology approach
1/03/21 → 1/03/24
Project: Internally funded project
Research output
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An ENT2-dependent, cell-penetrating, and DNA-damaging lupus autoantibody crosses the blood-brain barrier to target brain tumors
Rattray, Z., Deng, G., Zhang, S., Shirali, A., May, C., Liu, J., Zou, P., Cuffari, B., Rattray, N., Johnson, C., Dubljevic, V., Campbell, J., Huttner, A., Baehring, J., Zhou, J. & Hansen, J., 4 Aug 2020, In: Neuro-Oncology Advances. 2, Supplement 2, p. ii13-ii13 1 p.Research output: Contribution to journal › Meeting abstract › peer-review
Open Access -
Sex differences in colon cancer metabolism reveal a novel subphenotype
Cai, Y., Rattray, N. J. W., Zhang, Q., Mironova, V., Santos-Neto, A., Hsu, K-S., Rattray, Z., Cross, J. R., Zhang, Y., Paty, P. B., Khan, S. A. & Johnson, C. H., 17 Mar 2020, In: Scientific Reports. 10, 13 p., 4905.Research output: Contribution to journal › Article › peer-review
Open AccessFile6 Citations (Scopus)2 Downloads (Pure)
Activities
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Serum and sebum-based biomarker detection approaches for Parkinson’s Disease.
Nicholas Rattray (Speaker)
16 Feb 2021Activity: Talk or presentation types › Invited talk
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Using omics technologies to develop biomarkers of frailty
Nicholas Rattray (Speaker)
21 Feb 2021Activity: Talk or presentation types › Invited talk