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Research Output 2010 2018

2018
12 Citations (Scopus)

Enabling precision manufacturing of active pharmaceutical ingredients: workflow for seeded cooling continuous crystallisations

Brown, C. J., McGlone, T., Yerdelen, S., Srirambhatla, V., Mabbott, F., Gurung, R., Briuglia, M. L., Ahmed, B., Polyzois, H., Mcginty, J., Perciballi, F., Fysikopoulos, D., Macfhionnghaile, P., Siddique, H., Raval, V., Harrington, T. S., Vassileiou, A. D., Robertson, M., Prasad, E., Johnston, A. & 9 othersJohnston, B., Nordon, A., Srai, J. S., Halbert, G., ter Horst, J. H., Price, C. J., Rielly, C. D., Sefcik, J. & Florence, A. J., 1 Jun 2018, In : Molecular Systems Design and Engineering. 3, 3, p. 518-549 32 p.

Research output: Contribution to journalArticle

Open Access
File
Workflow
Crystallization
Drug products
Cooling
Pharmaceutical Preparations

Enabling precision manufacturing of active pharmaceutical ingredients: workflow for seeded cooling continuous crystallisation

Brown, C. J., McGlone, T., Yerdelen, S., Srirambhatla, V., Mabbott, F., Gurung, R., Briuglia, M. L., Ahmed, B., Polyzois, H., McGinty, J., Perciballi, F., Fysikopoulos, D., Macfhionnghaile, P., Siddique, H., Raval, V., Harrington, T. S., Vassileiou, A., Robertson, M., Prasad, E., Johnston, A. & 9 othersJohnston, B., Nordon, A., Srai, J., Halbert, G., Ter Horst, J. H., Price, C. J., Rielly, C. D., Sefcik, J. & Florence, A. J., 1 Jun 2018, In : Molecular Systems Design & Engineering. 2018, 3, p. 518-549 32 p.

Research output: Contribution to journalArticle

Open Access
File
Workflow
Crystallization
Cooling
Pharmaceutical Preparations
Process design
4 Citations (Scopus)
Open Access
File
Secondary Ion Mass Spectrometry
Surface Properties
Acetaminophen
Secondary ion mass spectrometry
secondary ion mass spectrometry
2017
3 Citations (Scopus)

Inhibitory Kappa B kinase α (IKKα) inhibitors that recapitulate their selectivity in cells against isoform-related biomarkers

Anthony, N. G., Baiget, J., Berretta, G., Boyd, M., Breen, D., Edwards, J., Gamble, C., Gray, A. I., Harvey, A. L., Hatziieremia, S., Ho, K. H., Huggan, J. K., Lang, S., Llona-Minguez, S., Luo, J. L., McIntosh, K., Paul, A., Plevin, R. J., Robertson, M. N., Scott, R. & 4 othersSuckling, C. J., Sutcliffe, O. B., Young, L. C. & MacKay, S. P., 24 Jul 2017, In : Journal of Medicinal Chemistry. 60, 16, p. 7043-7066 24 p.

Research output: Contribution to journalArticle

Open Access
File
Protein Isoforms
Phosphotransferases
Biomarkers
NF-kappa B
Phosphorylation
2016
85 Citations (Scopus)

Open source drug discovery: highly potent antimalarial compounds derived from the tres cantos arylpyrroles

Williamson, A. E., Ylioja, P. M., Robertson, M. N., Antonova-Koch, Y., Avery, V., Baell, J. B., Batchu, H., Batra, S., Burrows, J. N., Bhattacharyya, S., Calderon, F., Charman, S. A., Clark, J., Crespo, B., Dean, M., Debbert, S. L., Delves, M., Dennis, A. S. M., Deroose, F., Duffy, S. & 33 othersFletcher, S., Giaever, G., Hallyburton, I., Gamo, F-J., Gebbia, M., Guy, R. K., Hungerford, Z., Kirk, K., Lafuente-Monasterio, M. J., Lee, A., Meister, S., Nislow, C., Overington, J. P., Papadatos, G., Patiny, L., Pham, J., Ralph, S. A., Ruecker, A., Ryan, E., Southan, C., Srivastava, K., Swain, C., Tarnowski, M. J., Thomson, P., Turner, P., Wallace, I. M., Wells, T. N. C., White, K., White, L., Willis, P., Winzeler, E. A., Wittlin, S. & Todd, M. H., 26 Oct 2016, In : ACS central science. 2, 10, p. 687-701 15 p.

Research output: Contribution to journalArticle

Open Access
File
Antimalarials
Drug Discovery
Patents
Research
Liver
2015
Research Design
Crystallization
Research
Research Personnel
Technology
2010
3 Citations (Scopus)

The drug discovery portal: a computational platform for identifying drug leads from academia

Clark, R., Johnston, B., Mackay, S., Breslin, C., Robertson, M., Sutcliffe, O. B., Dufton, M. & Harvey, A., May 2010, In : Current Pharmaceutical Design. 16, 15, p. 1697-1702 6 p.

Research output: Contribution to journalArticle

Drug Discovery
Research
Pharmaceutical Preparations
Scotland
Libraries
3 Citations (Scopus)

The drug discovery portal: a computational platform for identifying drug leads from academia

Clark, R. L., Johnston, B. F., Mackay, S. P., Breslin, C. J., Robertson, M., Sutcliffe, O. B., Dufton, M. J. & Harvey, A. L., 2010, In : Current Pharmaceutical Design . 16, 15, p. 1697-1702 6 p.

Research output: Contribution to journalArticle

Drug Discovery
Research
Pharmaceutical Preparations
Scotland
Libraries
21 Citations (Scopus)

The drug discovery portal: a resource to enhance drug discovery from academia

Clark, R. L., Johnston, B. F., Mackay, S. P., Breslin, C. J., Robertson, M. N. & Harvey, A. L., Aug 2010, In : Drug Discovery Today. 15, 15-16, p. 679-683 5 p.

Research output: Contribution to journalLiterature review

Drug Discovery
Pharmaceutical Chemistry
Pharmaceutical Preparations
Industry
Research

The drug discovery portal library: a unique resource to enhance drug discovery in academia

Al-Shar'i, N., Al-Jaidi, B., Johnston, B. F., Robertson, M. N., Mackay, S. P. & Clark, R. L., Oct 2010, In : Journal of Pharmacy and Pharmacology. 62, 10 special issue, p. 1382-1382 1 p.

Research output: Contribution to journalMeeting abstract

Drug Discovery
Libraries