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Personal profile

Personal Statement

I’m a Senior Lecturer in the Departments of Electronic & Electrical Engineering and Biomedical Engineering. 

My research is concerned with microbial infection control, and the development of novel disinfection and sterilisation technologies for public health applications, with particular focus on healthcare-associated infections (HAI) – the most frequent adverse event in health-care delivery worldwide, with hundreds of millions of patients affected annually.  

My major research focus has been on the fundamental antimicrobial effects of violet-blue light and it's development as a cutting-edge decontamination technology for a range of infection control applications.

I have a highly interdisciplinary background, with a BSc in Immunology and Microbiology (2002), and a PhD focused on the interdisciplinary development of UV and visible-light for sterilisation and infection control applications (2006), which I conducted at The Robertson Trust Laboratory for Electronic Sterilisation Technologies (ROLEST), at Strathclyde.  After completion of my PhD I continued my research at ROLEST where I worked as a Research Fellow.  In 2014, I was appointed as a Lecturer through a Strathclyde Chancellors Fellowship, and I was promoted to Senior Lecturer in 2017.  I have more than 70 publications, including journals, conference proceedings and presentations at scientific and medical conferences, and also have a growing IP portfolio.

Expertise & Capabilities

  • applied microbiology
  • microbial inactivation
  • decontamination and sterilisation
  • infection control

Research Interests

I am based in The Robertson Trust Laboratory for Electronic Sterilisation Technologies (ROLEST), in the Department of Electronic & Electrical Engineering, and my research is focused on the development of novel disinfection and infection control intervention technologies for public health applications, including prevention of healthcare and food/waterborne infections.

The majority of my research to date has focused on investigations into the fundamental antimicrobial effects of 405 nm high-intensity narrow-spectrum (HINS) light.  Research has focused on determining antimicrobial sensitivity, wavelength sensitivity and the mechanism of inactivation.  Much work has been focused on establishing the effects of this antimicrobial light against key pathogens including MRSA and Clostridium difficile, and I am involved in the investigation and development of this light technology for a range of disinfection applications. 

One such example of this is the development of the HINS-light Environmental Decontamination System (EDS), a novel visible light system for continuous disinfection of occupied environments such as hospital isolation rooms.  This research project was awarded the Times Higher Education Award for ‘Research Project of the Year’ in 2011.   

I am also involved in the development of a number of other electro-technologies for development towards disinfection and sterilisation applications, including ultraviolet light, pulsed electric fields, oxidative corona and plasma technologies, and ozone.

Teaching Interests

I teach on a variety of modules in the Biomedical Engineering Department:

BE919 Research Methodology

BE428 Research Methods in Biomedical Engineering

BE207 Human Cell Biology 2

BE915 Medical Science for Engineering (Haematology and Immunology lectures)

BE101 Biomedical Engineering (sterilisation of devices lecture)

BE901 Regenerative Medicine & Tissue Engineering (sterilisation and decontamination lecture)

I also supervise a range of interdisciplinary students (EEE, BME, SIPBS) for their undergraduate and postgraduate research projects.

Education/Academic qualification

Doctor of Philosophy, University of Strathclyde

Bachelor of Science, University of Strathclyde

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Research Output

Non-ionizing 405nm light as a potential bactericidal technology for platelet safety: evaluation of in vitro bacterial inactivation and in vivo platelet recovery in severe combined immunodeficient mice

MacLean, M., Gelderman, M. P., Kulkarni, S., Tomb, R. M., Stewart, C. F., Anderson, J. G., MacGregor, S. J. & Atreya, C. D., 15 Jan 2020, In : Frontiers in Medicine. 6, 8 p., 331.

Research output: Contribution to journalArticle

Open Access
  • 15 Downloads (Pure)

    Surface design for immobilization of an antimicrobial peptide mimic for efficient anti‐biofouling

    Hasan, A., Lee, K., Tewari, K., Pandey, L. M., Messersmith, P. B., Faulds, K., MacLean, M. & Lau, K. H. A., 7 May 2020, In : Chemistry - A European Journal. 26, 26, p. 5789-5793 5 p.

    Research output: Contribution to journalArticle

    Open Access
  • 1 Citation (Scopus)


    Optimisation of 405 nm HINS-light technology for the development of patient-safe decontamination in arthroplasty surgery

    Author: Ramakrishnan, P., 19 May 2016

    Supervisor: Grant, M. (Supervisor) & MacLean, M. (Supervisor)

    Student thesis: Doctoral Thesis


    Research Project of the Year

    Michelle MacLean (Recipient), Scott MacGregor (Recipient), John Anderson (Recipient) & Gerry Woolsey (Recipient), 2011

    Prize: Prize (including medals and awards)

  • Activities

    • 1 Examination

    PhD External Examiner

    Michelle MacLean (External Examiner)
    11 Jan 2017

    Activity: Examination typesExamination