Projects per year
Personal profile
Personal Statement
Michele Zagnoni's research is based on the development of new microsystems for basic biology investigation, diagnosis and treatment of disease using microfluidic and lab-on-a-chip technologies. More information on: www.zagnonilab.com
Research Interests
We use microfluidics for the development of screening and diagnostic systems for healthcare applications, including fundamental biological research, drug screening and personalized medicine therapy, for the creation of organ-on-a-chip in vitro models and for synthetic biology applications.
Expertise & Capabilities
Microfabrication of polymeric structures
Theoretical and experimental expertise in fluid dynamics at the microscale
On chip cell culture
Organ on a chip
Bioimaging
Miniaturised bioassay
Academic / Professional qualifications
08/2013 Member of the EPSRC Peer Review College
06/2013 Affiliate Membership to the Royal Society of Chemistry
10/2012: SCQF Certificate for Biosafety Practitioner Level 1
10/2012: PostGraduate Certificate in Advanced Academic Studies
04/2006: Ph.D. degree in Electronic Engineering and Computer Science
11/2002: Italian state certification for the practice of engineering as a profession (Chartered Engineer)
10/2002: Dr. Eng. degree (5 year degree) in Electronic Engineering (Bioengineering qualification)
Teaching Interests
Teaching Staff for the course EE312 - Instrumentation and Microcontrollers (3rd year) at the University of Strathclyde.
Support Staff for the course EE105 - Electronic Techniques and Design (1st year) at the University of Strathclyde.
Teaching Staff for Small Group Tutorials (SGT) at the University of Strathclyde.
Keywords
- Microfluidics
- Lab on a chip
- Bioelectronics
- Bioengineering
- Synthetic Biology
- Biosensor
- Microfabrication
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Collaborations and top research areas from the last five years
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Development of 'human stroke-on-a-chip' model to replace rodent stroke models
Carswell, H. (Principal Investigator) & Zagnoni, M. (Co-investigator)
National Centre for the Replacement, Refinement and Reduction of Animals in Research NC3Rs
1/01/25 → 31/12/27
Project: Research - Studentship
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Engineering the Bone Marrow Niche to Control Stem Cell Regulation, Metastatic Evolution and Cancer Dormancy
Zagnoni, M. (Principal Investigator)
EPSRC (Engineering and Physical Sciences Research Council)
5/02/24 → 4/02/29
Project: Research
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Accelerating cytocompatible hydrogel discovery: assessment of multiplexing approaches to increase screening throughput
Sinclair, L., Zagnoni, M., Mosedale, C. & Sandison, M., 4 Sept 2025.Research output: Contribution to conference › Poster › peer-review
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A high-fidelity microfluidic platform reveals retrograde propagation as the main mechanism of α-Synuclein spread in human neurons
Vroman, R., de Lichtervelde, L., Singh Dolt, K., Robertson, G., Kriek, M., Barbato, M., Cholewa-Waclaw, J., Kunath, T., Downey, P. & Zagnoni, M., 20 Apr 2025, In: npj Parkinson's Disease. 11, 1, 14 p., 80.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)13 Downloads (Pure)
Datasets
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Data for: "A microfluidic platform for the characterisation of CNS active compounds"
MacKerron, C. (Creator), Robertson, G. (Creator), Zagnoni, M. (Creator) & Bushell, T. (Creator), University of Strathclyde, 30 Nov 2017
DOI: 10.15129/5a018c9b-9458-4e3f-8a92-23657abcd44e
Dataset
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Data for: "Detection of Estrogen Receptor Alpha and Assessment of Fulvestrant Activity in MCF-7 Tumour Spheroids Using Microfluidics and SERS"
Kapara, A. (Creator), Faulds, K. (Supervisor), Paterson, K. (Contributor), Brunton, V. (Contributor), Graham, D. (Contributor) & Zagnoni, M. (Contributor), University of Strathclyde, 15 Apr 2021
DOI: 10.15129/c3d04bd3-64ef-4e7f-9d72-2cd1a3254a2f
Dataset
Prizes
Activities
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PhD student selected for oral presentation at international conference due to outstanding abstract.
Carswell, H. (Contributor), Aruvornlop, P. (Invited speaker) & Zagnoni, M. (Contributor)
5 Sept 2023Activity: Talk or Presentation › Invited talk
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ORGAN-ON-A-CHIP TECHNOLOGIESFOR MEDICAL RESEARCH
Zagnoni, M. (Recipient)
Jun 2023 → …Activity: Public Engagement and Outreach › Media Participation