Research output per year
Research output per year
- 36 results
Search results
-
2023
Immunisation with transgenic L. tarentolae expressing gamma glutamyl cysteine synthetase from pathogenic Leishmania species protected against L. major and L. donovani infection in a murine model
Topuz Ata, D., Hussain, M., Jones, M., Best, J., Wiese, M. & Carter, K. C., 17 May 2023, In: Microorganisms. 11, 5, 17 p., 1322.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Citations (Scopus)43 Downloads (Pure) -
2022
Absence of DEATH kinesin is fatal for Leishmania mexicana amastigotes
Al Kufi, S. G. J., Emmerson, J., Rosenqvist, H., Garcia, C. M. M., Rios-Szwed, D. O. & Wiese, M., 28 Feb 2022, In: Scientific Reports. 12, 1, 13 p., 3266.Research output: Contribution to journal › Article › peer-review
Open AccessFile4 Citations (Scopus)30 Downloads (Pure) -
2020
Glycan–glycan interactions determine Leishmania attachment to the midgut of permissive sand fly vectors
Hall, A. R., Blakeman, J. T., Eissa, A. M., Chapman, P., Morales-García, A. L., Stennett, L., Martin, O., Giraud, E., Dockrell, D. H., Cameron, N. R., Wiese, M., Yakop, L., Rogers, M. E. & Geoghegan, M., 28 Oct 2020, In: Chemical Science. 11, 40, p. 10973-10983 11 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile7 Citations (Scopus)29 Downloads (Pure) -
2019
Leishmania donovani 90 kD heat shock protein - impact of phosphosites on parasite fitness, infectivity and casein kinase affinity
Hombach-Barrigah, A., Bartsch, K., Smirlis, D., Rosenqvist, H., MacDonald, A., Dingli, F., Loew, D., Späth, G. F., Rachidi, N., Wiese, M. & Clos, J., 25 Mar 2019, In: Scientific Reports. 9, 1, 16 p., 5074.Research output: Contribution to journal › Article › peer-review
Open AccessFile26 Citations (Scopus)50 Downloads (Pure) -
2016
An arginine deprivation response pathway is induced in Leishmania during macrophage invasion
Goldman-Pinkovich, A., Balno, C., Strasser, R., Zeituni-Molad, M., Bendelak, K., Rentsch, D., Ephros, M., Wiese, M., Jardim, A., Myler, P. J. & Zilberstein, D., 4 Apr 2016, In: PLOS Pathogens. 12, 4, 18 p., e1005494.Research output: Contribution to journal › Article › peer-review
Open AccessFile68 Citations (Scopus)196 Downloads (Pure) -
2014
Transgenic analysis of the Leishmania MAP kinase MPK10 reveals an auto-inhibitory mechanism crucial for stage-regulated activity and parasite viability
Cayla, M., Rachidi, N., Leclercq, O., Schmidt-Arras, D., Rosenqvist, H., Wiese, M. & Späth, G. F., 30 Sept 2014, In: PLOS Pathogens. 10, 9, 10 p., e1004347.Research output: Contribution to journal › Article › peer-review
Open AccessFile18 Citations (Scopus)176 Downloads (Pure) -
The Leishmania donovani chaperone cyclophilin 40 is essential for intracellular infection independent of its stage-specific phosphorylation status
Yau, W.-L., Pescher, P., MacDonald, A., Hem, S., Zander, D., Retzlaff, S., Blisnick, T., Rotureau, B., Rosenqvist, H., Wiese, M., Bastin, P., Clos, J. & Späth, G., 31 Jul 2014, In: Molecular Microbiology. 93, 1, p. 80–97 18 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile22 Citations (Scopus)138 Downloads (Pure) -
2012
Modulation of Leishmania major aquaglyceroporin activity by a mitogen-activated protein kinase
Mandal, G., Sharma, M., Kruse, M., Sander-Juelch, C., Munro, L. A., Wang, Y., Vilg, J. V., Tamás, M. J., Bhattacharjee, H., Wiese, M. & Mukhopadhyay, R., Sept 2012, In: Molecular Microbiology. 85, 6, p. 1204–1218 15 p.Research output: Contribution to journal › Article › peer-review
50 Citations (Scopus) -
The efficacy of aerosol treatment with non-ionic surfactant vesicles containing amphotericin B in rodent models of leishmaniasis and pulmonary aspergillosis infection
Alsaadi, M., Italia, J. L., Mullen, A., Kumar, M. N. V. R., Candlish, A. A., Williams, R., Shaw, C. D., Al-Gawhari, F., Coombs, G., Wiese, M., Thomson, A., Puig-Sellart, M., Wallace, J., Sharp, A., Wheeler, L., Warn, P. & Carter, K., 28 Jun 2012, In: Journal of Controlled Release. 160, 3, p. 685-691 7 p.Research output: Contribution to journal › Article › peer-review
46 Citations (Scopus) -
2010
Deletion of UDP-glucose pyrophosphorylase reveals a UDP-glucose independent UDP-galactose salvage pathway in Leishmania major
Lamerz, A.-C., Damerow, S., Kleczka, B., Wiese, M., van Zandbergen, G., Lamerz, J., Wenzel, A., Hsu, F.-F., Turk, J., Beverley, S. M. & Routier, F. H., Jul 2010, In: Glycobiology. 20, 7, p. 872-882 11 p.Research output: Contribution to journal › Article › peer-review
19 Citations (Scopus) -
LmxMPK4, an essential mitogen-activated protein kinase of Leishmania mexicana is phosphorylated and activated by the STE7-like protein kinase LmxMKK5
von Freyend, S. J., Rosenqvist, H., Fink, A., Melzer, I. M., Clos, J., Jensen, O. N. & Wiese, M., Jul 2010, In: International Journal for Parasitology. 40, 8, p. 969-978 10 p.Research output: Contribution to journal › Article › peer-review
20 Citations (Scopus) -
2009
Trypanosomatid protein kinases as potential drug targets
Wiese, M., Morris, A. & Grant, K. M., Apr 2009, Antiparasitic and Antibacterial Drug Discovery: From Molecular Targets to Drug Candidates. Selzer , P. M. (ed.). John Wiley & Sons Inc., p. 227-276 50 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter
2 Citations (Scopus) -
2008
Involvement of a Leishmania thymidine kinase in flagellum formation, promastigote shape and growth as well as virulence
Thiel, M., Harder, S., Wiese, M., Kroemer, M. & Bruchhaus, I., Apr 2008, In: Molecular and Biochemical Parasitology. 158, 2, p. 152-162 10 p.Research output: Contribution to journal › Article › peer-review
18 Citations (Scopus) -
2007
Leishmania MAP kinases-familiar proteins in an unusual context
Wiese, M., Aug 2007, In: International Journal for Parasitology. 37, 10, p. 1053-62 10 p.Research output: Contribution to journal › Article › peer-review
72 Citations (Scopus) -
Targeted gene deletion of leishmania major UDP-galactopyranose mutase leads to attenuated virulence
Kleczka, B., Lamerz, A.-C., van Zandbergen, G., Wenzel, U., Gerardy-Schahn, R., Wiese, M. & Routier, F. H., 6 Apr 2007, In: Journal of Biological Chemistry. 282, 14, p. 10498-10505 7 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile72 Citations (Scopus)18 Downloads (Pure) -
2006
Interacting protein kinases involved in the regulation of flagellar length
Erdmann, M., Scholz, M., Melzer, I. M., Schmetz, C. & Wiese, M., 2006, In: Molecular Biology of the Cell. 17, 4, p. 2035-2045 10 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile74 Citations (Scopus)359 Downloads (Pure) -
2005
LmxMPK4, a mitogen-activated protein (MAP) kinase homologue essential for promastigotes and amastigotes of Leishmania mexicana
Wang, Q., Melzer, I. M., Kruse, M., Sander-Juelch, C. & Wiese, M., 29 Dec 2005, In: Kinetoplastid Biology and Disease. 4, 9 p., 6.Research output: Contribution to journal › Article › peer-review
43 Citations (Scopus) -
Binding affinity and capacity of putative adaptor-mediated sorting of a Type I membrane protein in Leishmania mexicana
Weise, F., Thilo, L., Engstler, M., Wiese, M., Benzel, I., Kühn, C., Bühring, H.-J. & Overath, P., Aug 2005, In: Molecular and Biochemical Parasitology. 142, 2, p. 203-11 9 p.Research output: Contribution to journal › Article › peer-review
6 Citations (Scopus) -
LmxPK4, a mitogen-activated protein kinase kinase homologue of Leishmania mexicana with a potential role in parasite differentiation
Kuhn, D. & Wiese, M., 30 Jun 2005, In: Molecular Microbiology. 56, 5, p. 1169-1182 14 p.Research output: Contribution to journal › Article › peer-review
41 Citations (Scopus) -
LmxMPK9, a mitogen-activated protein kinase homologue affects flagellar length in leishmania mexicana
Bengs, F., Scholz, A., Kuhn, D. & Wiese, M., 2005, In: Molecular Microbiology. 55, 5, p. 1606-1615 10 p.Research output: Contribution to journal › Article › peer-review
109 Citations (Scopus) -
2003
Identification of mitogen-activated protein kinase homologues from Leishmania mexicana
Wiese, M., Wang, Q. & Görcke, I., Dec 2003, In: International Journal for Parasitology. 33, 14, p. 1577-1587 11 p.Research output: Contribution to journal › Article › peer-review
28 Citations (Scopus) -
Protein kinase involved in flagellar-length control
Wiese, M., Kuhn, D. & Grunfelder, C. G., 2003, In: Eukaryotic cell. 2, 4, p. 769-777 9 p.Research output: Contribution to journal › Article › peer-review
76 Citations (Scopus) -
2001
Early response gene expression during differentiation of cultured Leishmania donovani
Duncan, R., Alvarez, R., Jaffe, C. L., Wiese, M., Klutch, M., Shakarian, A., Dwyer, D. & Nakhasi, H. L., Nov 2001, In: Parasitology Research. 87, 11, p. 897-906 10 p.Research output: Contribution to journal › Article › peer-review
23 Citations (Scopus) -
Homologues of LMPK, a mitogen-activated protein kinase from Leishmania mexicana, in different Leishmania species
Wiese, M. & Görcke, I., Nov 2001, In: Medical Microbiology and Immunology. 190, 1-2, p. 19-22 4 p.Research output: Contribution to journal › Article › peer-review
12 Citations (Scopus) -
2000
Distribution of GPI-anchored proteins in the protozoan parasite Leishmania, based on an improved ultrastructural description using high-pressure frozen cells
Weise, F., Stierhof, Y. D., Kühn, C., Wiese, M. & Overath, P., Dec 2000, In: Journal of Cell Science. 113 Pt 24, p. 4587-4603 17 p.Research output: Contribution to journal › Article › peer-review
84 Citations (Scopus) -
Deletion of the gene for the membrane-bound acid phosphatase of Leishmania mexicana
Benzel, I., Weise, F. & Wiese, M., Nov 2000, In: Molecular and Biochemical Parasitology. 111, 1, p. 77-86 10 p.Research output: Contribution to journal › Article › peer-review
22 Citations (Scopus) -
Subunit vaccination of mice against new world cutaneous leishmaniasis: comparison of three proteins expressed in amastigotes and six adjuvants
Aebischer, T., Wolfram, M., Patzer, S. I., Ilg, T., Wiese, M. & Overath, P., Mar 2000, In: Infection and Immunity . 68, 3, p. 1328-1336 9 p.Research output: Contribution to journal › Article › peer-review
49 Citations (Scopus) -
1999
Expression and species-specific glycosylation of Leishmania mexicana secreted acid phosphatase in Leishmania major
Wiese, M., Görcke, I. & Overath, P., 20 Aug 1999, In: Molecular and Biochemical Parasitology. 102, 2, p. 325-329 5 p.Research output: Contribution to journal › Article › peer-review
6 Citations (Scopus) -
1998
Structure of a filamentous phosphoglycoprotein polymer: the secreted acid phosphatase of Leishmania mexicana
Stierhof, Y. D., Wiese, M., Ilg, T., Overath, P., Häner, M. & Aebi, U., 11 Sept 1998, In: Journal of Molecular Biology . 282, 1, p. 137-148 12 p.Research output: Contribution to journal › Article › peer-review
20 Citations (Scopus) -
A mitogen-activated protein (MAP) kinase homologue of Leishmania mexicana is essential for parasite survival in the infected host
Wiese, M., 1 May 1998, In: The EMBO journal. 17, 9, p. 2619-2628 10 p.Research output: Contribution to journal › Article › peer-review
144 Citations (Scopus) -
1997
Endocytosis and secretion in trypanosomatid parasites - Tumultuous traffic in a pocket
Overath, P., Stierhof, Y. D. & Wiese, M., Jan 1997, In: Trends in Cell Biology. 7, 1, p. 27-33 7 p.Research output: Contribution to journal › Article › peer-review
125 Citations (Scopus) -
1996
Antigen presentation by Leishmania mexicana-infected macrophages: activation of helper T cells by a model parasite antigen secreted into the parasitophorous vacuole or expressed on the amastigote surface
Wolfram, M., Fuchs, M., Wiese, M., Stierhof, Y. D. & Overath, P., Dec 1996, In: European Journal of Immunology. 26, 12, p. 3153-3162 10 p.Research output: Contribution to journal › Article › peer-review
38 Citations (Scopus) -
Gene cloning and cellular localization of a membrane-bound acid phosphatase of Leishmania mexicana
Wiese, M., Berger, O., Stierhof, Y.-D., Wolfram, M., Fuchs, M. & Overath, P., 25 Nov 1996, In: Molecular and Biochemical Parasitology. 82, 2, p. 153-165 13 p.Research output: Contribution to journal › Article › peer-review
41 Citations (Scopus) -
1995
Ser/Thr-rich repetitive motifs as targets for phosphoglycan modifications in Leishmania mexicana secreted acid phosphatase
Wiese, M., Ilg, T., Lottspeich, F. & Overath, P., 15 Mar 1995, In: The EMBO journal. 14, 6, p. 1067-1074 8 p.Research output: Contribution to journal › Article › peer-review
83 Citations (Scopus) -
1994
Characterization of phosphoglycan-containing secretory products of Leishmania
Ilg, T., Stierhof, Y. D., Wiese, M., McConville, M. J. & Overath, P., Mar 1994, In: Parasitology. 108, S1, p. S63-71Research output: Contribution to journal › Article › peer-review
68 Citations (Scopus) -
1993
Monoclonal antibodies directed against Leishmania secreted acid phosphatase and lipophosphoglycan. Partial characterization of private and public epitopes
Ilg, T., Harbecke, D., Wiese, M. & Overath, P., 15 Oct 1993, In: European Journal of Biochemistry . 217, 2, p. 603-15 13 p.Research output: Contribution to journal › Article › peer-review
57 Citations (Scopus)