Projects per year
Dr Marie Boyd joined SIPBS from the CRUK Beatson Laboratories in July 2009 as a SULSA Reader in Translational Biology. Dr Boyd was awarded a CRUK Senior Cancer Research Fellowship in 2005 to investigate targeted radionuclide therapy for cancer. Targeted radionuclide therapy utilised radiation like a drug, that is molecules which are accrued specifically in tumours have a radioactive molecule attached, and once the radiopharmaceutical is injected into the body and it gets concentrated only in tumour cells. This results in irradiation specifically to tumour cells sparing normal tissues and thus reduction of toxic side effects. Our research group focuses on expansion of this form of radiotherapy to more tumour types by investigation and development of novel radiopharmaceuticals and targets as well as by adopting gene therapy techniques.
The group also investigates the basic biology of cellular response to radiotherapy and have a large area of research into combining radiotherapy with novel and existing drugs and interrogation of cell signaling and mechanisms using traditional and “Omics” based approaches. The Boyd group have already translated some therapeutic schemes into clinical trial and other promising schemes based upon repurposing of existing drugs, are underway with Industrial partners including AstraZeneca.
Since the transfer to Strathclyde, the group has established several cross-disciplinary links within the TIC themes in areas of advanced Sciences and Technologies, Bionanotechnology, and Health Technologies at Strathclyde. These collaborations are formed around the need to establish multidisciplinary approaches to the development of cancer therapy. Our work fosters the marriage of cancer biology and radiobiology with platform technologies such as Laser Plasma Wakefield Accelerators, microfluidics, biogels and the combinations of novel and existing drugs and nanomaterials in the SU pipeline with chemo- and radiotherapy produced by a variety of radiation sources. The group will also be integral to the new TIC building hosting the SCAPA (Scottish centre for applied particle accelerators) facility. This research environment is a resource which is unique to Strathclyde University.
The Group is highly active within the recently established RICAS (Research In Cancer at Strathclyde) initiative, has been highly successful in achieving multi-disciplinary, Industry and clinical linked funding. The breadth of research has also recently expanded by involvement in the SIPBS led multi-university programme in pharmacoepidemiology. With our partners we are interrogating prescribing databases to interrogate questions which may lead to the development of better and more personalised cancer therapeutics. The group is also involved with several drug discovery programmes within and outwith the university and has developed phenotypic assay cascades to aid these programmes.
Dr Boyd's group is highly active in the research, industrial and clinical arena and the lab hosts senior fellows, Post docs, PhD students, research assistants, undergraduate and students from within SIPBS and from other University Departments (Physics, chemistry, EEE). The Boyd group will also host vertically Integrated Studentships (VIPs) within the lab, which are being run in collaboration with Chemistry and EEE and we are becoming partners in the Laser Plasma Accelerator Doctoral training centre spearheaded by the university.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
- Cancer therapy
- radiation oncology
- drug discovery
- combination therapy
- drug delivery
- peadiatric cancer
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Developing Aberdeen's Cancer Research Network
Spiers, V., kiltie, A., Gomez-Roman, N., Boyd, M., Tomlinson, I. P. M., Gourley, C., Machesky, L., Chalmers, A., Broche, L. & Stansfield, I.
1/10/22 → 30/09/23
Project: Knowledge Exchange
Understanding radiation response and cell cycle variation in brain tumour cells using Raman spectroscopyHill, I. E., Boyd, M., Milligan, K., Jenkins, C. A., Sorensen, A., Jirasek, A., Graham, D. & Faulds, K., 7 Jun 2023, In: Analyst. 148, 11, p. 2594-2608 15 p.
Research output: Contribution to journal › Article › peer-reviewOpen AccessFile6 Downloads (Pure)
Comparing trastuzumab-related cardiotoxicity between elderly and younger patients with breast cancer: a prospective cohort studyAladwani, A., Mullen, A., Alrashidi, M., Alfarisi, O., Alterkait, F., Aladwani, A., Kumar, A., Boyd, M. & Eldosouky, M. E., 31 Dec 2021, In: European Review for Medical and Pharmacological Sciences. 25, 24, p. 7643-7653 11 p.
Research output: Contribution to journal › Article › peer-reviewOpen AccessFile
Data for: "Understanding Radiation Response and Cell Cycle Variation in Brain Tumour Cells using Raman Spectroscopy"
Hill, I. (Creator), Boyd, M. (Creator), Milligan, K. (Creator), Jenkins, C. A. (Creator), Sorensen, A. (Creator), Graham, D. (Creator), Faulds, K. (Supervisor) & Jirasek, A. (Creator), University of Strathclyde, 21 Sept 2022
Invited Trustee and Scientific Advisory Committee of the LH Gray Trust
Boyd, Marie (Recipient), 2008
Prize: Election to learned society
NCRI ‚Radiation Research
Boyd, Marie (Recipient), 2009
Prize: Election to learned society
Management Science (Organisational unit)
Ioanna Fragkandrea Nixon (Chair), Alec Morton (Member), Roma Maguire (Member), Jens Sutter (Member), Marie Boyd (Member) & Stuart Forsyth (Member)2020
Activity: Membership types › Membership of committee
Marie Boyd (Visiting researcher)Jan 2015 → …
Activity: Visiting an external institution types › Visiting an external academic institution
MicrocentrifugeStrathclyde Institute Of Pharmacy And Biomedical Sciences