Research output per year
Research output per year
- 1 - 50 out of 54 results
Search results
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2024
Bad to the bone: an RNA-sequencing study identifying a role for IKK-alpha in osteosarcoma cell division and progression
Tinto, K., Bonfanti, M., Cunningham, M. R. & Plevin, R., 4 Sept 2024.Research output: Contribution to conference › Presentation/Speech › peer-review
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Altered regulation of Ca2+ handling proteins in an in vivo rat model of Angiotensin II-induced hypertension
Olatunji, Z., BOSAKHAR, Z. Y. H. A. H. A., MacKenzie, G., Cunningham, M. R., MacQuaide, N. & Currie, S., 28 Aug 2024, In: Medical Science Forum. 27, (1) 3, 2.27.Research output: Contribution to journal › Conference abstract › peer-review
Open Access -
Recounting the untold stories of breast cancer patient experiences: lessons learned from a patient-public involvement and engagement (PPIE) storytelling event
Cunningham, M. R., Rattray, N. J. W., McFadden, Y., Berardi, D., Daramy, K., Kelly, P. E., Galbraith, A., Lochiel, I., Mills, L., Scott, Y., Chalmers, S., Lannigan, A. & Rattray, Z., 1 Aug 2024, (Accepted/In press) In: International Journal of Pharmacy Practice. 9 p., riae052.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Recounting the untold stories of breast cancer
Cunningham, M. R. & Rattray, Z., 11 Jun 2024.Research output: Contribution to conference › Presentation/Speech
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Defining and unpacking the core concepts of pharmacology: a global initiative
Guilding, C., White, P. J., Cunningham, M., Kelly-Laubscher, R., Koenig, J., Babey, A. M., Tucker, S., Kelly, J. P., Gorman, L., Aronsson, P., Hawes, M., Ngo, S. N. T., Mifsud, J., Werners, A. H., Hinton, T., Khan, F., Aljofan, M. & Angelo, T., Feb 2024, In: British Journal of Pharmacology. 181, 3, p. 375-392 18 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile8 Citations (Scopus)6 Downloads (Pure) -
2023
Altered regulation of cardiac calcium handling proteins in an in vivo rat model of angiotensin-induced hypertension
Olatunji, Z. O., Bosakhar, Z., MacKenzie, G., Cunningham, M., Macquaide, N. & Currie, S., 4 Sept 2023. 1 p.Research output: Contribution to conference › Poster › peer-review
Open AccessFile37 Downloads (Pure) -
A novel role for IL-1b in non-canonical NFkB signalling in U20S cells
Tinto, K., McIntosh, K., Cunningham, M. R. & Plevin, R., 31 Jul 2023.Research output: Contribution to conference › Abstract › peer-review
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HMGB1 release in the cardiac niche: interplay between HMGB1 and thrombin
Bosakhar, Z., MacKenzie, G., Gu, H., Currie, S. & Cunningham, M., 31 Jul 2023, In: British Journal of Pharmacology. 180, S1, p. 140 1 p., P0589.Research output: Contribution to journal › Conference abstract › peer-review
Open Access -
TAK1 is an upstream MAP 3 K regulator of a novel non-canonical NFkB pathway stimulated by IL-1b
Farhan, M., McIntosh, K. A., Cunningham, M. R., Plevin, R. & Tinto, K., 31 Jul 2023, In: British Journal of Pharmacology. 180, S1, p. 708-709 2 p., OC143.Research output: Contribution to journal › Conference abstract › peer-review
Open Access -
Concept mapping in pharmacology: quantitative evaluation and qualitative reflection
Bremner, S., Klemm, N., Ford, S., Cunningham, M. R. & Plevin, R., 1 Jul 2023.Research output: Contribution to conference › Poster
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Utilising storytelling to reveal the untold stories of breast cancer
Hill, M., Cunningham, M. R. & Rattray, Z., 1 Jul 2023. 1 p.Research output: Contribution to conference › Poster
Open AccessFile28 Downloads (Pure) -
Exploring protease signalling within the cell, a focus on mitochondrial PAR4
Bonfanti, M., Qu, T., Gould, G. W. & Cunningham, M. R., 27 Jun 2023, In: British Journal of Pharmacology. 180, p. 669-670 1 p., P0404.Research output: Contribution to journal › Conference abstract › peer-review
Open Access -
TAK-1 inhibition prevents cytokine-mediated CXCL12 production in a bone cancer cell line
Farhan, M., Cunningham, M. R., McIntosh, K. & Plevin, R., 27 Jun 2023, In: British Journal of Pharmacology. 180, 1 p., OC012.Research output: Contribution to journal › Conference Contribution › peer-review
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A roadmap for patient-public involvement and engagement (PPIE): recounting the untold stories of breast cancer patient experiences
Cunningham, M. R., Rattray, N. JW., McFadden, Y., Berardi, D., Kelly, P. E., Daramy, K., Galbraith, A., Lochiel, I., Mills, L., Scott, Y., Chalmers, S., Lannigan, A. & Rattray, Z., 19 Jun 2023, Ithaca, New York, p. 1-16, 16 p.Research output: Working paper › Working Paper/Preprint
Open AccessFile102 Downloads (Pure) -
Identifying the core concepts of pharmacology education: a global initiative
White, P., Guilding, C., Angelo, T., Kelly, J., Gorman, L., Tucker, S., Fun, A., Han, J., Chen, G., Samak, Y., Babey, A-M., Caetano, F., Sarangi, S., Keonig, J., Hao, H., Goldfarb, J., Karpa, K., Vieira, L., Restini, C., Cunningham, M., & 13 others, 31 May 2023, In: British Journal of Pharmacology. 180, 9, p. 1197-1209 13 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile8 Citations (Scopus)22 Downloads (Pure) -
2022
Anti-Cancer Drug-Induced Cardiotoxicity
Currie, S. (ed.), Cunningham, M. R. (ed.), Cross, M. (ed.) & Maddock, H. L. (ed.), 30 Sept 2022, Switzerland: Frontiers Media S.A. 161 p.Research output: Book/Report › Book
Open Access -
2021
Sustainable Impact by Design
Essex, J., Wellisch, G., Galbraith, A., Egea Alvarez, A., Cunningham, M. R., Giovelli, N., Ivaturi, A., Li, R., Maddock, C., Somorin, T., Yue, H., Hendry, P., Hendry, M., Essex, W., Caccavale, E. & Johnson, M. P., 30 Sept 2021, 70 p. Glasgow : University of Strathclyde.Research output: Other contribution
Open AccessFile90 Downloads (Pure) -
Different responses of the blockade of the P2Y1 receptor with BPTU in human and porcine intestinal tissues and in cell cultures
Traserra, S., Barber, C., MacInnes, J., Relea, L., MacPherson, L. C., Cunningham, M. R., Vergara, P., Accarino, A., Kennedy, C. & Jimenez, M., Jul 2021, In: Neurogastroenterology and Motility. 33, 7, e14101.Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Citations (Scopus)33 Downloads (Pure) -
A new model for regulation of sphingosine kinase 1 translocation to the plasma membrane in breast cancer cells
Brown, R. D. R., Veerman, B. E. P., Oh, J., Tate, R. J., Torta, F., Cunningham, M. R., Adams, D. R., Pyne, S. & Pyne, N. J., 16 Apr 2021, In: Journal of Biological Chemistry. 32 p., 100674.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Citations (Scopus)30 Downloads (Pure) -
On synthetic instrument response functions of time-correlated single-photon counting based fluorescence lifetime imaging analysis
Xiao, D., Sapermsap, N., Safar, M., Cunningham, M. R., Chen, Y. & Li, D. D-U., 2 Mar 2021, In: Frontiers in Physics. 9, 11 p., 635645.Research output: Contribution to journal › Article › peer-review
Open AccessFile7 Citations (Scopus)161 Downloads (Pure) -
Sunitinib and imatinib display differential cardiotoxicity in adult rat cardiac fibroblasts that involves a role for calcium/calmodulin dependent protein kinase II
McMullen, C. J., Chalmers, S., Wood, R., Cunningham, M. R. & Currie, S., 1 Feb 2021, In: Frontiers in Cardiovascular Medicine. 7, 15 p., 630480.Research output: Contribution to journal › Article › peer-review
Open AccessFile15 Citations (Scopus)52 Downloads (Pure) -
2020
The development of proteinase-activated receptor-2 modulators and the challenges involved
McIntosh, K. A., Cunningham, M. R., Bushell, T. & Plevin, R., 31 Dec 2020, In: Biochemical Society Transactions. 48, 6, p. 2525-2537 13 p., BST20200191.Research output: Contribution to journal › Review article › peer-review
Open AccessFile23 Citations (Scopus)241 Downloads (Pure) -
Investigations on average fluorescence lifetimes for visualizing multi-exponential decays
Li, Y., Natakorn, S., Chen, Y., Safar, M., Cunningham, M., Tian, J. & Li, D. D-U., 16 Oct 2020, In: Frontiers in Physics. 8, 13 p., 576862.Research output: Contribution to journal › Article › peer-review
Open AccessFile44 Citations (Scopus)977 Downloads (Pure) -
Interrogating purinergic P2Y1 and P2Y12 heterodimerisation
Safar, M., Tate, R., Sapermsap, N., Li, D., Cunningham, M. & Kennedy, C., 14 Oct 2020.Research output: Contribution to conference › Poster › peer-review
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Dysregulation of endothelial cell connexin-43 localisation in response to doxorubicin
Veerman, B., McGivern, S-J., Dempsie, Y., Martin, P. E. M., Johnston, B., Currie, S. & Cunningham, M. R., 5 Apr 2020, In: Heart . 106, 1, 1 p., 11.Research output: Contribution to journal › Conference abstract › peer-review
Open AccessFile28 Downloads (Pure) -
Sunitinib mediates mitochondrial ROS production in adult rat cardiac fibroblasts via CaMKII oxidation
McMullen, CJ., Chalmers, S., Cunningham, MR. & Currie, S., 5 Apr 2020, In: Heart . 106, Suppl 1, 1 p., OP8.Research output: Contribution to journal › Conference abstract › peer-review
Open AccessFile36 Downloads (Pure) -
2019
P2Y1 and P2Y12 receptor heterodimerisation: from recombinant systems to native detection
Safar, M. A., Wood, R., Cunningham, M. R. & Kennedy, C., 1 Aug 2019, In: British Journal of Pharmacology. 176, 16, p. 3049 1 p.Research output: Contribution to journal › Conference abstract › peer-review
Open AccessFile42 Downloads (Pure) -
Assessment of adult rat cardiac fibroblast viability following chronic sunitinib treatment
McMullen, C. J., Wood, R. A., Cunningham, M. R. & Currie, S., 1 May 2019, In: Heart . 105, suppl 4, p. A6-A7 2 p.Research output: Contribution to journal › Conference abstract › peer-review
Open AccessFile8 Citations (Scopus)41 Downloads (Pure) -
2018
P2Y1and P2Y12 receptor heterodimerisation: from recombinant systems to native detection
Safar, M. A. A., Wood, R. A. (ed.), Tate, R. (ed.), Cunningham, M. R. & Kennedy, C. (ed.), 4 Dec 2018.Research output: Contribution to conference › Presentation/Speech › peer-review
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P2Y1 and P2Y12 receptor heterodimerisation: from recombinant systems to native detection
Safar, M. A. A., Wood, R. A. (ed.), Tate, R. (ed.), Cunningham, M. R. & Kennedy, C. (ed.), 2 Dec 2018.Research output: Contribution to conference › Presentation/Speech
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Heterodimerisation of purinergic GPCRs
Safar, M. A. A., Wood, R. A. (ed.), Cunningham, M. R. & Kennedy, C. (ed.), 15 Nov 2018.Research output: Contribution to conference › Poster › peer-review
12 Downloads (Pure) -
CaMKIIδ interacts directly with IKKβ and modulates NF-kB signalling in adult cardiac fibroblasts
Martin, T. P., McCluskey, C., Cunningham, M. R., Beattie, J., Paul, A. & Currie, S., 27 Jul 2018, (E-pub ahead of print) In: Cellular Signalling.Research output: Contribution to journal › Article › peer-review
Open AccessFile20 Citations (Scopus)44 Downloads (Pure) -
Anti-cancer tyrosine kinase inhibitors increase oxidative stress in primary cardiac fibroblasts
McMullen, CJ., McCluskey, C., Kim, SJ., Laovitthayanggoon, S., MacDonald, M., Safar, M., Wood, R., Cunningham, MR. & Currie, S., 26 Mar 2018, In: Heart . 104, S4, 1 p.Research output: Contribution to journal › Conference abstract › peer-review
Open Access -
Conflicting evidence for the role of JNK as a target in breast cancer cell proliferation: comparisons between pharmacological inhibition and selective shRNA knockdown approaches
Wood, R. A., Barbour, M. J., Gould, G. W., Cunningham, M. R. & Plevin, R. J., 28 Feb 2018, In: Pharmacology Research & Perspectives. 6, 1, 10 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile5 Citations (Scopus)105 Downloads (Pure) -
2017
Editorial for Pharmacology Matters
Cunningham, M., 25 Jul 2017, In: Pharmacology Matters. 10, 2, 1 p.Research output: Contribution to journal › Editorial
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Pathophysiological consequences of receptor mistraffic: tales from the platelet P2Y12 receptor
Cunningham, M., Aungraheeta, R. & Mundell, S. J., 14 Feb 2017, In: Molecular and Cellular Endocrinology. p. 1-23 23 p.Research output: Contribution to journal › Review article › peer-review
Open AccessFile7 Citations (Scopus)48 Downloads (Pure) -
2016
Protease-activated receptor 4 variant p.Tyr157Cys reduces platelet functional responses and alters receptor trafficking
Norman, J. E., Cunningham, M. R., Jones, M. L., Walker, M. E., Westbury, S. K., Sessions, R. B., Mundell, S. J. & Mumford, A. D., 1 May 2016, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 36, 5, p. 952-960 9 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile16 Citations (Scopus)56 Downloads (Pure) -
Proteinase-activated receptors (PARs) as targets for antiplatelet therapy
Cunningham, M., McIntosh, K., Bushell, T., Sloan, G. & Plevin, R., 15 Apr 2016, In: Biochemical Society Transactions. 44, 2, p. 606-612 7 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile15 Citations (Scopus)161 Downloads (Pure) -
Protease-activated receptor 2: are common functions in glial and immune cells linked to inflammation-related CNS disorders?
Bushell, T. J., Cunningham, M. R., McIntosh, K. A., Moudio, S. & Plevin, R., 2016, In: Current Drug Targets. 17, 16, p. 1861-1870 10 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile14 Citations (Scopus)274 Downloads (Pure) -
2015
Identification and characterization of novel variations in platelet G-protein coupled receptor (GPCR) genes in patients historically diagnosed with type 1 von Willebrand disease: GPCR variations in type 1 von Willebrand disease
Stockley, J., Nisar, S. P., Leo, V. C., Sabi, E., Cunningham, M. R., Eikenboom, J. C., Lethagen, S., Schneppenheim, R., Goodeve, A. C., Watson, S. P., Mundell, S. J., Daly, M. E. & on behalf of the GAPP study in collaboration with the MCMDM-1VWD study group, 2 Dec 2015, In: PLoS ONE. 10, 12, 15 p., e0143913.Research output: Contribution to journal › Article › peer-review
Open AccessFile6 Citations (Scopus)118 Downloads (Pure) -
Rare platelet G protein-coupled receptor variants: what can we learn?
Nisar, S. P., Jones, M. L., Cunningham, M. R., Mumford, A. D., Mundell, S. J. & UK GAPP Study Group, 2015, In: British Journal of Pharmacology.Research output: Contribution to journal › Article › peer-review
Open AccessFile10 Citations (Scopus)101 Downloads (Pure) -
2014
A novel thromboxane A2 receptor N42S variant results in reduced surface expression and platelet dysfunction
Nisar, S. P., Lordkipanidzé, M., Jones, M. L., Dawood, B., Murden, S., Cunningham, M. R., Mumford, A. D., Wilde, J. T., Watson, S. P., Mundell, S. J., Lowe, G. C. & UK GAPP Study Group, 5 May 2014, In: Thrombosis and haemostasis. 111, 5, p. 923-932 10 p.Research output: Contribution to journal › Article › peer-review
22 Citations (Scopus) -
2013
Ethanol reversal of cellular tolerance to morphine in rat locus coeruleus neurons
Llorente, J., Withey, S., Rivero, G., Cunningham, M., Cooke, A., Saxena, K., McPherson, J., Oldfield, S., Dewey, W. L., Bailey, C. P., Kelly, E. & Henderson, G., Aug 2013, In: Molecular Pharmacology. 84, 2, p. 252-260 9 p.Research output: Contribution to journal › Article › peer-review
11 Citations (Scopus) -
Differential endosomal sorting of a novel P2Y12 purinoreceptor mutant
Cunningham, M. R., Nisar, S. P., Cooke, A. E., Emery, E. D. & Mundell, S. J., May 2013, In: Traffic. 14, 5, p. 585-598 14 p.Research output: Contribution to journal › Article › peer-review
13 Citations (Scopus) -
How GPCRs changed my life
Cunningham, M. R., Apr 2013, In: Pharmacology Matters. 6, 1, p. 12-13 2 p.Research output: Contribution to journal › Special issue
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Molecular mechanisms of platelet P2Y(12) receptor regulation
Cunningham, M. R., Nisar, S. P. & Mundell, S. J., 1 Feb 2013, In: Biochemical Society Transactions. 41, 1, p. 225-230 6 p.Research output: Contribution to journal › Article › peer-review
28 Citations (Scopus) -
2012
Endocytosis of G protein-coupled receptors is regulated by clathrin light chain phosphorylation
Ferreira, F., Foley, M., Cooke, A., Cunningham, M., Smith, G., Woolley, R., Henderson, G., Kelly, E., Mundell, S. & Smythe, E., 7 Aug 2012, In: Current Biology. 22, 15, p. 1361-1370 10 p.Research output: Contribution to journal › Article › peer-review
38 Citations (Scopus) -
Arrestin scaffolds NHERF1 to the P2Y12 receptor to regulate receptor internalization
Nisar, S. P., Cunningham, M., Saxena, K., Pope, R. J., Kelly, E. & Mundell, S. J., 13 Jul 2012, In: Journal of Biological Chemistry. 287, 29, p. 24505-24515 11 p.Research output: Contribution to journal › Article › peer-review
32 Citations (Scopus) -
Novel role for proteinase-activated receptor 2 (PAR2) in membrane trafficking of proteinase-activated receptor 4 (PAR4)
Cunningham, M. R., McIntosh, K. A., Pediani, J. D., Robben, J., Cooke, A. E., Nilsson, M., Gould, G. W., Mundell, S., Milligan, G. & Plevin, R., 11 May 2012, In: Journal of Biological Chemistry. 287, 20, p. 16656-16669 14 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile37 Citations (Scopus)405 Downloads (Pure) -
2010
Proteinase-activated receptor-2 mediated inhibition of TNFα-stimulated JNK activation — A novel paradigm for Gq/11 linked GPCRs
McIntosh, K., Cunningham, M. R., Cadalbert, L., Lochart, J., Boyd, G., Ferrell, W. R. & Plevin, R. J., Feb 2010, In: Cellular Signalling. 22, 2, p. 265-273 8 p.Research output: Contribution to journal › Article › peer-review
7 Citations (Scopus)