Projects per year
My research focuses on exploiting microengineering approaches (lab-on-a-chip, microfluidics, materials engineering) to create new in vitro models for investigating and controlling cell behaviours. Applications of this work include the development of tools for drug screening and for tissue engineering, with a particular focus on vascular cell biology.
Current research projects are focussed upon combining lab-on-a-chip approaches and material functionalisation with live-cell imaging to:
- investigate the phenotypic changes in vascular cells that underlie cardiovascular disease
- develop new methods for monitoring mitochondrial dynamics in neuronal preparations
- develop physiologically relevant, in vitro model systems
I have taught on both the BEng/MEng and MSc courses in Biomedical Engineering and I am currently module coordinator for BE105 (Cell Biology 1).
1/10/20 → 1/10/24
Project: Research Studentship - Internally Allocated
Development of novel, automated analyses for the quantification of cellular and sub-cellular dynamics from fluorescence video-microscopy
1/09/20 → 11/09/21
Project: Internally funded project
MYC regulates fatty acid metabolism through a multigenic program in claudin-low triple negative breast cancerCasciano, J. C., Perry, C., Cohen-Nowak, A. J., Miller, K. D., Voorde, J. V., Zhang, Q., Chalmers, S., Sandison, M. E., Lui, Q., Hedley, A., McBryan, T., Tang, H-Y., Gorman, N., Beer, T., Speicher, D. W., Adams, P. D., Lui, X., Schlegel, R., McCarron, J. G., Wakelam, M. J. O. & 3 others, , 17 Mar 2020, In: British Journal of Cancer. 122, 6, p. 868-884 17 p.
Research output: Contribution to journal › Article › peer-reviewOpen AccessFile9 Citations (Scopus)13 Downloads (Pure)
An in vitro tissue-based model of vascular remodeling in the descending aorta at intercostal artery branch pointsSandison, M., 11 Apr 2019. 1 p.
Research output: Contribution to conference › Abstract › peer-review