Projects per year
My research focuses on exploiting microsystems engineering approaches (lab-on-a-chip, microfluidics, materials engineering) to create new in vitro models for investigating and controlling cell behaviours. Applications of this work include the development of tools for drug screening and for tissue engineering, with a particular focus on vascular cell biology. My background is highly interdisciplinary, spanning the engineering-life science interface, with expertise in a wide range of cell biology, microfabrication, live-cell imaging and analytical technologies.
Current research projects, involving collaboration with a diverse range of academic and clinical collaborators, include:
- investigating the phenotypic changes in vascular cells that underlie cardiovascular disease
- the development of organ-on-a-chip models for chronic gynaecological conditions
- the development of new methods for monitoring mitochondrial dynamics in neuronal preparations.
I have taught on both the BEng/MEng and MSc courses in Biomedical Engineering and I am currently module coordinator for BE105 (Cell Biology 1).
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1/10/20 → 1/10/24
Project: Research Studentship - Internally Allocated
Development of novel, automated analyses for the quantification of cellular and sub-cellular dynamics from fluorescence video-microscopy
1/09/20 → 11/09/21
Project: Internally funded project
Metal oxide-doped elastomeric materials for enhancement of 405-nm light-based antimicrobial surface decontaminationMcShea, L., Kambo, H., Maclean, M. & Sandison, M., 11 Nov 2020, p. 145. 1 p.
Research output: Contribution to conference › Poster › peer-review
MYC regulates fatty acid metabolism through a multigenic program in claudin-low triple negative breast cancerCasciano, J. C., Perry, C., Cohen-Nowak, A. J., Miller, K. D., Voorde, J. V., Zhang, Q., Chalmers, S., Sandison, M. E., Lui, Q., Hedley, A., McBryan, T., Tang, H-Y., Gorman, N., Beer, T., Speicher, D. W., Adams, P. D., Lui, X., Schlegel, R., McCarron, J. G., Wakelam, M. J. O. & 3 others, , 17 Mar 2020, In: British Journal of Cancer. 122, 6, p. 868-884 17 p.
Research output: Contribution to journal › Article › peer-reviewOpen AccessFile