Projects per year
Personal profile
Personal Statement
Lian obtained his PhD in Mechanical Engineering from the University of Colorado at Boulder in 2010. He then took his first postdoctoral training in Biomedical Engineering at the University of Wisconsin-Madison in USA and his second postdoctoral training in cardiovascular biology in the Department of Medicine at Queen's University in Canada. He Joined SIPBS in 2020. His research interests focus on cardiovascular physiology, biomechanics, biology and modeling, particularly in pulmonary hypertension. The goal is to understand the mechanism at molecular, cellular, tissue and organ levels for disease diagnosis, monitoring and therapeutic treatment. His group has recently focused on right ventricular fibrosis and function in pulmonary arterial hypertension.
PhD and postdoctoral positions are available to work on the following projects:
1. Sex-dependent mitochondrial function in the right ventricle in pulmonary arterial hypertension
2. Right ventricular ischemia and function in pulmonary arterial hypertension
3. Cardiovascular physiology, biomechanics and modeling
Applicants who are interested in cardiovascular physiology and biology are encouraged to contact Dr. Lian Tian.
Research Interests
Cardiovascular physiology, biomechanics, biology and modeling in pulmonary hypertension
Education/Academic qualification
Doctor of Philosophy, University of Colorado
Sep 2006 → Dec 2010
Award Date: 17 Dec 2010
Master of Science, University of British Columbia
Sep 2004 → Jul 2006
Award Date: 17 Nov 2006
Bachelor of Science, University of Science and Technology of China
Sep 1999 → Jul 2003
Award Date: 2 Jul 2003
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Projects
- 2 Active
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Sex-dependent mitochondrial function in right ventricle in pulmonary arterial hypertension
1/05/21 → 31/10/21
Project: Research
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Doctoral Training Partnership 2020-2021 University of Strathclyde | Coyle, Chelbi
Bushell, T., Plevin, R., Tian, L., MacLean, M. & Coyle, C.
EPSRC (Engineering and Physical Sciences Research Council)
1/10/20 → 1/04/24
Project: Research Studentship - Internally Allocated
Research output
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Oxygen sensing, mitochondrial biology and experimental therapeutics for pulmonary hypertension and cancer
Wu, D., Dasgupta, A., Read, A. D., Bentley, R. E. T., Motamed, M., Chen, K-H., Al-Qazazi, R., Mewburn, J. D., Dunham-Snary, K. J., Alizadeh, E., Tian, L. & Archer, S. L., 12 Jan 2021, In: Free Radical Biology and Medicine. 29 p.Research output: Contribution to journal › Article › peer-review
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Epigenetic metabolic reprogramming of right ventricular fibroblasts in pulmonary arterial hypertension: a pyruvate dehydrogenase kinase-dependent shift in mitochondrial metabolism promotes right ventricular fibrosis
Tian, L., Wu, D., Dasgupta, A., Chen, K-H., Mewburn, J., Potus, F., Lima, P. D. A., Hong, Z., Zhao, Y-Y., Hindmarch, C. C. T., Kutty, S., Provencher, S., Bonnet, S., Sutendra, G. & Archer, S. L., 5 Jun 2020, In: Circulation Research. 126, 12, p. 1723-1745 23 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile11 Citations (Scopus)17 Downloads (Pure)
Prizes
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AHA 3CPR Cournand and Comroe Young Investigator Award Finalist
Tian, Lian (Recipient), 2015
Prize: Prize (including medals and awards)
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AHA 3CPR Junior Investigator Travel Stipend
Tian, Lian (Recipient), 2016
Prize: Prize (including medals and awards)
Activities
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Targeting right ventricular ischemia, fibrosis and diastolic dysfunction in pulmonary arterial hypertension
Lian Tian (Speaker)
11 Feb 2021Activity: Talk or presentation types › Invited talk
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Frontiers Research Topic (Journal)
Lian Tian (Guest editor)
20 Apr 2020 → 15 Mar 2021Activity: Publication peer-review and editorial work types › Journal or guest editorship