Projects per year
Personal profile
Personal Statement
Group website: www.mackenzie-lab.org
Dr Lewis E. MacKenzie is a Royal Society University Research Fellow & Chancellor's Fellow in the Department of Pure and Applied Chemistry, leading an interdisciplinary research team. The team’s research focuses on the development of nanosensors for biosensing, with a current focus on non-invasive measurement of blood and tissue oxygenation. The end-goal of this research is to improve the efficiency quality of hypoxia measurements in biomedical research. Dr MacKenzie is also interested in biophotonics, imaging, spectroscopy, microscopy, circularly polarised luminescence for chiral molecules, optical instrumentation, and science communication. Dr MacKenzie can offer project opportunities for masters-level and PhD students. Please email directly for details.
Career Timeline:
2025 - 2033. Royal Society University Research Fellow (Department of Pure and Applied Chemistry).
2021 onwards: Chancellor’s Fellow (Department of Pure and Applied Chemistry, University of Strathclyde).
2020 – 2023: BBSRC Discovery Fellow (initially hosted by the Pal group at Durham, then as independent group leader at Strathclyde from 2021 onwards).
2017 – 2020: Postdoctoral Research Associate (Pal group, Department of Chemistry, Durham University).
2016 – 2017: Postdoctoral Research Fellow (Millner BioNanoTechnology Group, School of Biomedical Science, University of Leeds).
2012 – 2016: PhD Researcher (Imaging Concepts Group, School of Physics and Astronomy, University of Glasgow)
Research Interests
The MacKenzie NanoBioPhotonics group currently focus on these interdisciplinary research themes:
- Upconversion nanoparticles: synthesis, design, and functionalization.
- Nanobiosensing: oxygen measurement in blood, cells, and tissue.
- Applied optics: imaging and spectroscopy
- Chiral nanomaterials and chiral spectroscopy, particularly circularly polarised luminescence.
- Quantitative science communication: science podcast and chemistry YouTube channels
For a detailed breakdown, please visit:
Academic / Professional qualifications
2025. Associate Fellowship of the Higher Education Academy. Advance HE. In recognition of attainment against the Professional Standards Framework for teaching and learning support in higher education
Ph.D. 2016. School of Physics and Astronomy, University of Glasgow. Thesis title: 'In vivo oximetry using multispectral imaging'. Supervisor: Prof. Andy Harvey.
M.Sc. Astrophysics. 2012. School of Physics and Astronomy, University of Glasgow.
B.Sc. (Hons). Physics and Astronomy. 2011. School of Physics and Astronomy, University of Glasgow.
Expertise & Capabilities
Upconversion nanoparticles, nanosensors, biophotonics, blood oximetry, tissue optics, imaging, optical instrumentation, spectroscopy, chiral spectroscopy, circularly polarised luminescence (CPL), science communication and new media.
Teaching Interests
Dr MacKenzie currently teaches CH213 'Handling Chemical Data and Mathematics' as part of the level 2 undergraduate Chemistry curriculum.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Bachelor of Science, Physics and Astronomy (2011), University of Glasgow
Master in Science, MSc Astrophysics (2012), University of Glasgow
Doctor of Science, In vivo microvascular oximetry using multispectral imaging (2016), University of Glasgow
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Collaborations and top research areas from the last five years
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Cancer-Targeting Upconversion Nanoparticles to Track-and-Treat Glioblastoma
MacKenzie, L. (Principal Investigator), Chow, S. (Co-investigator) & Gomez-Roman, N. (Co-investigator)
1/10/25 → 31/03/27
Project: Research
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Breaking Barriers in Upconversion Nanoparticle Research: Improving Accessibility and Enabling (University Research Fellowship)
MacKenzie, L. (Principal Investigator)
1/10/25 → 30/09/33
Project: Research Fellowship
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Observation of Rayleigh optical activity for chiral molecules: a new chiroptical tool
McArthur, D., Alexakis, E. I., Puente, A. R., McGonigle, R., Love, A. J., Polavarapu, P. L., Barron, L. D., MacKenzie, L. E., Arnold, A. S. & Cameron, R. P., 4 Dec 2025, (E-pub ahead of print) In: Journal of Physical Chemistry A. 2 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Observation of Rayleigh optical activity for chiral molecules: a new chiroptical tool
McArthur, D., Alexakis, E. I., Puente, A. R., McGonigle, R., Love, A. J., Polavarapu, P., Barron, L. D., MacKenzie, L. E., Arnold, A. S. & Cameron, R. P., 26 Jul 2025, Ithaca, NY, 2 p.Research output: Working paper › Working Paper/Preprint
Open AccessFile13 Downloads (Pure)
Datasets
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Supporting data and software for: Low-temperature open-air synthesis of PVP-coated NaYF4:Yb,Er,Mn upconversion nanoparticles with strong red emission
MacKenzie, L. (Creator), Àlvarez Ruiz, D. (Creator) & Pal, R. (Creator), Zenodo, 29 Aug 2023
Dataset
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Supplementary material from "Low-temperature open-air synthesis of PVP-coated NaYF4:Yb,Er,Mn upconversion nanoparticles with strong red emission"
Mackenzie, L. E. (Contributor), Alvarez-Ruiz, D. (Creator) & Pal, R. (Creator), figshare, 29 Aug 2023
DOI: 10.6084/m9.figshare.c.5767123.v1
Dataset
Prizes
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Análise de mais de 1600 canais de química no Youtube de 2005 a 2023
MacKenzie, L. (Speaker)
18 Jun 2025Activity: Talk or Presentation › Invited talk
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Exciting Upconversion Nanoparticles
MacKenzie, L. (Speaker)
18 Feb 2025Activity: Talk or Presentation › Invited talk