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19992020

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2020

A high-throughput genomic screen identifies a role for the plasmid-borne type II secretion system of Escherichia coli O157:H7 (Sakai) in plant-microbe interactions

Holmes, A., Pritchard, L., Hedley, P. E., Morris, J., McAteer, S. P., Gally, D. L. & Holden, N. J., 12 Jul 2020, In : Genomics. 112, 6, p. 4242-4253 12 p.

Research output: Contribution to journalArticle

Dataset of Escherichia coli O157: H7 genes enriched in adherence to spinach root tissue

Holmes, A., Pritchard, L., Hedley, P., Morris, J., McAteer, S. P., Gally, D. L. & Holden, N. J., 31 Aug 2020, In : Data in Brief. 31, 5 p., 105769.

Research output: Contribution to journalArticle

Open Access
File
1 Downloads (Pure)

Diversity of woody-host infecting Phytophthora species in public parks and botanic gardens as revealed by metabarcoding, and opportunities for mitigation through best practice

Green, S., Riddell, C. E., Frederickson-Matika, D., Armstrong, A., Elliot, M., Forster, J., Hedley, P. E., Morris, J., Thorpe, P., Cooke, D. E. L., Sharp, P. & Pritchard, L., 21 Feb 2020, In : Sibbaldia. 18, p. 67-88 22 p.

Research output: Contribution to journalArticle

Open Access
File
1 Downloads (Pure)

Pectobacterium parvum sp. nov. having a Salmonella SPI-1-like Type III secretion system and low virulence

Pasanen, M., Waleron, M., Schott, T., Cleenwerk, I., Misztak, A., Waleron, K., Pritchard, L., Bakr, R., Degefu, Y., van der Wolf, J., Vandamme, P. & Pirhonen, M., 20 Feb 2020, In : International Journal of Systematic and Evolutionary Microbiology. 70, 4, p. 2440-2448 9 p.

Research output: Contribution to journalArticle

Open Access
File
1 Citation (Scopus)
3 Downloads (Pure)
2019

Metabarcoding reveals a high diversity of woody host-associated Phytophthora spp. in soils at public gardens and amenity woodlands in Britain

Riddell, C. E., Frederickson-Matika, D., Armstrong, A. C., Elliot, M., Forster, J., Hedley, P. E., Morris, J., Thorpe, P., Cooke, D. EL., Pritchard, L., Sharp, P. M. & Green, S., 16 May 2019, In : PeerJ. 7, 31 p., e6931.

Research output: Contribution to journalArticle

Open Access
File
1 Downloads (Pure)

Toward collaborative open data science in metabolomics using Jupyter Notebooks and cloud computing

Mendez, K. M., Pritchard, L., Reinke, S. N. & Broadhurst, D. I., 31 Oct 2019, In : Metabolomics. 15, 16 p., 125.

Research output: Contribution to journalArticle

Open Access
File
3 Citations (Scopus)
27 Downloads (Pure)
2018

Absence of curli in soil-persistent Escherichia coli is mediated by a C-di-GMP signaling defect and suggests evidence of biofilm-independent niche specialization

Somorin, Y. M., Vollmerhausen, T., Waters, N., Pritchard, L., Abram, F., Brennan, F. & O'Byrne, C., 22 Jun 2018, In : Frontiers in Microbiology. 9, 13 p., 1340.

Research output: Contribution to journalArticle

Open Access
File
1 Citation (Scopus)
4 Downloads (Pure)

riboSeed: leveraging prokaryotic genomic architecture to assemble across ribosomal regions

Waters, N. R., Abram, F., Brennan, F., Holmes, A. & Pritchard, L., 20 Jun 2018, In : Nucleic Acids Research. 46, 11, 10 p., e68.

Research output: Contribution to journalArticle

Open Access
File
1 Citation (Scopus)
1 Downloads (Pure)

Toward assessing farm-based anaerobic digestate public health risks: comparative investigation with slurry, effect of pasteurization treatments, and use of miniature bioreactors as proxies for pathogen spiking trials

Nolan, S., Waters, N. R., Brennan, F., Auer, A., Fenton, O., Richards, K., Bolton, D. J., Pritchard, L., O'Flaherty, V. & Abram, F., 20 Jul 2018, In : Frontiers in Sustainable Food Systems. 2, 11 p., 41.

Research output: Contribution to journalArticle

Open Access
File
5 Citations (Scopus)
5 Downloads (Pure)
2017

Metagenomic analysis of the gut microbiome of the common black slug arion ater in search of novel lignocellulose degrading enzymes

Joynson, R., Pritchard, L., Osemwekha, E. & Ferry, N., 8 Nov 2017, In : Frontiers in Microbiology. 8, 11 p., 2181.

Research output: Contribution to journalArticle

Open Access
File
4 Citations (Scopus)
6 Downloads (Pure)
2015

Detection of the bacterial potato pathogens pectobacterium and dickeya spp. using conventional and real-time PCR

Humphris, S. N., Cahill, G., Elphinstone, J. G., Kelly, R., Parkinson, N. M., Pritchard, L., Toth, I. K. & Saddler, G. S., 1 Jan 2015, In : Methods in Molecular Biology. 1302, p. 1-16 17 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Epidemiology of Dickeya dianthicola and Dickeya solani in ornamental hosts and potato studied using variable number tandem repeat analysis

Parkinson, N., Pritchard, L., Bryant, R., Toth, I. & Elphinstone, J., 31 Jan 2015, In : European Journal of Plant Pathology. 141, 1, p. 63-70 8 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Why genomics research on pectobacterium and dickeya makes a difference

Toth, I., Humphris, S., Campbell, E. & Pritchard, L., 12 Mar 2015, In : American Journal of Potato Research. 92, 2, p. 218-222 5 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)
2014

Dickeya solani sp. nov., a pectinolytic plant-pathogenic bacterium isolated from potato (Solanum tuberosum)

van der Wolf, J. M., Nijhuis, E. H., Kowalewska, M. J., Saddler, G. S., Parkinson, N., Elphinstone, J. G., Pritchard, L., Toth, I. K., Lojkowska, E., Potrykus, M., Waleron, M., de Vos, P., Cleenwerck, I., Pirhonen, M., Garlant, L., Hélias, V., Pothier, J. F., Pflüger, V., Duffy, B., Tsror, L. & 1 others, Manulis, S., 1 Mar 2014, In : International Journal of Systematic and Evolutionary Microbiology. 64, 3, p. 768-774 7 p.

Research output: Contribution to journalArticle

109 Citations (Scopus)

The zigzag model of plant-microbe interactions: is it time to move on?

Pritchard, L. & Birch, P. R. J., 9 Nov 2014, In : Molecular Plant Pathology. 15, 9, p. 865-870 6 p.

Research output: Contribution to journalArticle

Open Access
31 Citations (Scopus)
2013

An RxLR effector from Phytophthora infestans prevents re-localisation of two plant NAC transcription factors from the endoplasmic reticulum to the nucleus

McLellan, H., Boevink, P. C., Armstrong, M. R., Pritchard, L., Gomez, S., Morales, J., Whisson, S. C., Beynon, J. L. & Birch, P. R. J., 10 Oct 2013, In : PLOS Pathogens. 9, 10, 16 p., e1003670.

Research output: Contribution to journalArticle

Open Access
File
107 Citations (Scopus)
3 Downloads (Pure)

Detection of phytopathogens of the genus Dickeya using a PCR primer prediction pipeline for draft bacterial genome sequences

Pritchard, L., Humphris, S., Saddler, G. S., Parkinson, N. M., Bertrand, V., Elphinstone, J. G. & Toth, I. K., 30 Jun 2013, In : Plant Pathology. 62, 3, p. 587-596 10 p.

Research output: Contribution to journalArticle

57 Citations (Scopus)

Draft genome sequences of 17 isolates of the plant pathogenic bacterium Dickeya

Pritchard, L., Humphris, S., Saddler, G. S., Elphinstone, J. G., Pirhonen, M. & Toth, I. K., 21 Nov 2013, In : Genome Announcements. 1, 6, 2 p., e00978-13.

Research output: Contribution to journalArticle

Open Access
File
15 Citations (Scopus)
1 Downloads (Pure)

Draft genome sequences of four Dickeya dianthicola and four Dickeya solani strains

Pritchard, L., Humphris, S., Baeyen, S., Maes, M., Van Vaerenbergh, J., Elphinstone, J., Saddler, G. & Toth, I., 25 Jul 2013, In : Genome Announcements. 1, 4, 2 p., e00087-12.

Research output: Contribution to journalArticle

Open Access
File
24 Citations (Scopus)

Galaxy tools and workflows for sequence analysis with applications in molecular plant pathology

Cock, P. J. A., Grüning, B. A., Paszkiewicz, K. & Pritchard, L., 17 Sep 2013, In : PeerJ. 22 p., e167.

Research output: Contribution to journalArticle

Open Access
File
78 Citations (Scopus)
1 Downloads (Pure)

Resistance gene enrichment sequencing (RenSeq) enables reannotation of the NB-LRR gene family from sequenced plant genomes and rapid mapping of resistance loci in segregating populations

Jupe, F., Witek, K., Verweij, W., Śliwka, J., Pritchard, L., Etherington, G. J., Maclean, D., Cock, P. J., Leggett, R. M., Bryan, G. J., Cardle, L., Hein, I. & Jones, J. D. G., 30 Nov 2013, In : Plant Journal. 76, 3, p. 530-544 15 p.

Research output: Contribution to journalArticle

Open Access
File
153 Citations (Scopus)
1 Downloads (Pure)

Using tablet for visual exploration of second-generation sequencing data

Milne, I., Stephen, G., Bayer, M., Cock, P. J. A., Pritchard, L., Cardle, L., Shawand, P. D. & Marshall, D., 31 Mar 2013, In : Briefings in Bioinformatics. 14, 2, p. 193-202 10 p.

Research output: Contribution to journalArticle

446 Citations (Scopus)
2012

Alignment-free design of highly discriminatory diagnostic primer sets for Escherichia coli O104:H4 outbreak strains

Pritchard, L., Holden, N. J., Bielaszewska, M., Karch, H. & Toth, I. K., 5 Apr 2012, In : PLoS ONE. 7, 4, 8 p., e34498.

Research output: Contribution to journalArticle

Open Access
File
22 Citations (Scopus)
1 Downloads (Pure)

Genetic characterization of the HrpL regulon of the fire blight pathogen Erwinia amylovora reveals novel virulence factors

McNally, R. R., Toth, I. K., Cock, P. J. A., Pritchard, L., Hedley, P. E., Morris, J. A., Zhao, Y. & Sundin, G. W., 29 Feb 2012, In : Molecular Plant Pathology. 13, 2, p. 160-173 14 p.

Research output: Contribution to journalArticle

Open Access
File
44 Citations (Scopus)
11 Downloads (Pure)

Genome-wide analysis of the response of Dickeya dadantii 3937 to plant antimicrobial peptides

Rio-Alvarez, I., Rodríguez-Herva, J. J., Cuartas-Lanza, R., Toth, I., Pritchard, L., Rodríguez-Palenzuela, P. & López-Solanilla, E., 30 Apr 2012, In : Molecular Plant-Microbe Interactions. 25, 4, p. 523-533 11 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Identification and localisation of the NB-LRR gene family within the potato genome

Jupe, F., Pritchard, L., Etherington, G. J., MacKenzie, K., Cock, P. JA., Wright, F., Sharma, S. K., Bolser, D., Bryan, G. J., Jones, J. DG. & Hein, I., 15 Feb 2012, In : BMC Genomics. 13, 14 p., 75.

Research output: Contribution to journalArticle

Open Access
File
163 Citations (Scopus)
2011

Presence/absence, differential expression and sequence polymorphisms between PiAVR2 and PiAVR2-like in Phytophthora infestans determine virulence on R2 plants

Gilroy, E. M., Breen, S., Whisson, S. C., Squires, J., Hein, I., Kaczmarek, M., Turnbull, D., Boevink, P. C., Lokossou, A., Cano, L. M., Morales, J., Avrova, A. O., Pritchard, L., Randall, E., Lees, A., Govers, F., van West, P., Kamoun, S., Vleeshouwers, V. G. A. A., Cooke, D. E. L. & 1 others, Birch, P. R. J., 31 Aug 2011, In : New Phytologist. 191, 3, p. 763-776 14 p.

Research output: Contribution to journalArticle

80 Citations (Scopus)
2010

Genome-wide identification of HrpL-regulated genes in the necrotrophic phytopathogen Dickeya dadantii 3937

Yang, S., Peng, Q., Zhang, Q., Zou, L., Li, Y., Robert, C., Pritchard, L., Liu, H., Hovey, R., Wang, Q., Birch, P., Toth, I. K. & Yang, C-H., 19 Oct 2010, In : PLoS ONE. 5, 10, 10 p., e13472.

Research output: Contribution to journalArticle

Open Access
File
16 Citations (Scopus)
2009

Corrigendum: Bacterial chemoattraction towards jasmonate plays a role in the entry of Dickeya dadantii through wounded tissues

Antunez-Lamas, M., Cabrera, E., Lopez-Solanilla, E., Solano, R., González-Melendi, P., Chico, J. M., Toth, I., Birch, P., Pritchard, L., Liu, H. & Rodriguez-Palenzuela, P., 31 Dec 2009, In : Molecular Microbiology. 74, 6, p. 1543-1543 1 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Genome sequence and analysis of the Irish potato famine pathogen Phytophthora infestans

Haas, B. J., Kamoun, S., Zody, M. C., Jiang, R. H. Y., Handsaker, R. E., Cano, L. M., Grabherr, M., Kodira, C. D., Raffaele, S., Torto-Alalibo, T., Bozkurt, T. O., Ah-Fong, A. M. V., Alvarado, L., Anderson, V. L., Armstrong, M. R., Avrova, A., Baxter, L., Beynon, J., Boevink, P. C., Bollmann, S. R. & 76 others, Bos, J. I. B., Bulone, V., Cai, G., Cakir, C., Carrington, J. C., Chawner, M., Conti, L., Costanzo, S., Ewan, R., Fahlgren, N., Fischbach, M. A., Fugelstad, J., Gilroy, E. M., Gnerre, S., Green, P. J., Grenville-Briggs, L. J., Griffith, J., Grünwald, N. J., Horn, K., Horner, N. R., Hu, C-H., Huitema, E., Jeong, D-H., Jones, A. M. E., Jones, J. D. G., Jones, R. W., Karlsson, E. K., Kunjeti, S. G., Lamour, K., Liu, Z., Ma, L., MacLean, D., Chibucos, M. C., McDonald, H., McWalters, J., Meijer, H. J. G., Morgan, W., Morris, P. F., Munro, C. A., O'Neill, K., Ospina-Giraldo, M., Pinzón, A., Pritchard, L., Ramsahoye, B., Ren, Q., Restrepo, S., Roy, S., Sadanandom, A., Savidor, A., Schornack, S., Schwartz, D. C., Schumann, U. D., Schwessinger, B., Seyer, L., Sharpe, T., Silvar, C., Song, J., Studholme, D. J., Sykes, S., Thines, M., van de Vondervoort, P. J. I., Phuntumart, V., Wawra, S., Weide, R., Win, J., Young, C., Zhou, S., Fry, W., Meyers, B. C., van West, P., Ristaino, J., Govers, F., Birch, P. R. J., Whisson, S. C., Judelson, H. S. & Nusbaum, C., 9 Sep 2009, In : Nature. 461, 7262, p. 393-398 6 p.

Research output: Contribution to journalArticle

Open Access
863 Citations (Scopus)

Microarray comparative genomic hybridisation analysis incorporating genomic organisation, and application to enterobacterial plant pathogens

Pritchard, L., Liu, H., Booth, C., Douglas, E., François, P., Schrenzel, J., Hedley, P. E., Birch, P. R. J. & Toth, I. K., 21 Aug 2009, In : PLoS Computational Biology. 5, 8, 17 p., e1000473.

Research output: Contribution to journalArticle

Open Access
File
7 Citations (Scopus)

Towards understanding the virulence functions of RXLR effectors of the oomycete plant pathogen Phytophthora infestans

Birch, P. R. J., Armstrong, M., Bos, J., Boevink, P., Gilroy, E. M., Taylor, R. M., Wawra, S., Pritchard, L., Conti, L., Ewan, R., Whisson, S. C., van West, P., Sadanandom, A. & Kamoun, S., 31 Mar 2009, In : Journal of Experimental Botany. 60, 4, p. 1133-1140 8 p.

Research output: Contribution to journalArticle

64 Citations (Scopus)
2008

Quorum sensing coordinates brute force and stealth modes of infection in the plant pathogen Pectobacterium atrosepticum

Liu, H., Coulthurst, S. J., Pritchard, L., Hedley, P. E., Ravensdale, M., Humphris, S., Burr, T., Takle, G., Brurberg, M-B., Birch, P. R. J., Salmond, G. P. C. & Toth, I. K., 20 Jun 2008, In : PLOS Pathogens. 4, 6, 11 p., e1000093.

Research output: Contribution to journalArticle

Open Access
File
160 Citations (Scopus)
2007

A novel non-protein-coding infection-specific gene family is clustered throughout the genome of Phytophthora infestans

Avrova, A. O., Whisson, S. C., Pritchard, L., Venter, E., De Luca, S., Hein, I. & Birch, P. R. J., 1 Mar 2007, In : Microbiology. 153, 3, p. 747-759 13 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)

A translocation signal for delivery of oomycete effector proteins into host plant cells

Whisson, S. C., Boevink, P. C., Moleleki, L., Avrova, A. O., Morales, J. G., Gilroy, E. M., Armstrong, M. R., Grouffaud, S., van West, P., Chapman, S., Hein, I., Toth, I. K., Pritchard, L. & Birch, P. R. J., 30 Sep 2007, In : Nature. 450, p. 115-118 4 p.

Research output: Contribution to journalArticle

505 Citations (Scopus)

Efflux pump gene expression in Erwinia chrysanthemi is induced by exposure to phenolic acids

Ravirala, R. S., Barabote, R. D., Wheeler, D. M., Reverchon, S., Tatum, O., Malouf, J., Liu, H., Pritchard, L., Hedley, P. E., Birch, P. R. J., Toth, I. K., Payton, P. & San Francisco, M. J. D., 1 Mar 2007, In : Molecular Plant-Microbe Interactions. 20, 3, p. 313-320 8 p.

Research output: Contribution to journalArticle

35 Citations (Scopus)

Expressed sequence tag (EST) analysis of the pine wood nematode Bursaphelenchus xylophilus and B. mucronatus

Kikuchi, T., Aikawa, T., Kosaka, H., Pritchard, L., Ogura, N. & Jones, J. T., 30 Sep 2007, In : Molecular and Biochemical Parasitology. 155, 1, p. 9-17 9 p.

Research output: Contribution to journalArticle

68 Citations (Scopus)

Involvement of cathepsin B in the plant disease resistance hypersensitive response

Gilroy, E. M., Hein, I., Van Der Hoorn, R., Boevink, P. C., Venter, E., McLellan, H., Kaffarnik, F., Hrubikova, K., Shaw, J., Holeva, M., López, E. C., Borras-Hidalgo, O., Pritchard, L., Loake, G. J., Lacomme, C. & Birch, P. R. J., 31 Oct 2007, In : Plant Journal. 52, 1, p. 1-13 13 p.

Research output: Contribution to journalArticle

113 Citations (Scopus)
2006

GenomeDiagram: a python package for the visualization of large-scale genomic data

Pritchard, L., White, J. A., Birch, P. R. J. & Toth, I. K., 1 Mar 2006, In : Bioinformatics. 22, 5, p. 616-617 2 p.

Research output: Contribution to journalArticle

50 Citations (Scopus)

Trafficking arms: oomycete effectors enter host plant cells

Birch, P. R. J., Rehmany, A. P., Pritchard, L., Kamoun, S. & Beynon, J. L., 1 Jan 2006, In : Trends in Microbiology. 14, 1, p. 8-11 4 p.

Research output: Contribution to journalArticle

211 Citations (Scopus)
2005

A general model of error-prone PCR

Pritchard, L., Corne, D., Kell, D., Rowland, J. & Winson, M., 21 Jun 2005, In : Journal of Theoretical Biology. 234, 4, p. 497-509 13 p.

Research output: Contribution to journalArticle

38 Citations (Scopus)

An ancestral oomycete locus contains late blight avirulence gene Avr3a, encoding a protein that is recognized in the host cytoplasm

Armstrong, M. R., Whisson, S. C., Pritchard, L., Bos, J. I. B., Venter, E., Avrova, A. O., Rehmany, A. P., Böhme, U., Brooks, K., Cherevach, I., Hamlin, N., White, B., Fraser, A., Lord, A., Quail, M. A., Churcher, C., Hall, N., Berriman, M., Huang, S., Kamoun, S. & 2 others, Beynon, J. L. & Birch, P. R. J., 24 May 2005, In : Proceedings of the National Academy of Sciences of the United States of America. 102, 21, p. 7766-7771 6 p.

Research output: Contribution to journalArticle

323 Citations (Scopus)

Families of short interspersed elements in the genome of the oomycete plant pathogen, Phytophthora infestans

Whisson, S. C., Avrova, A. O., Lavrova, O. & Pritchard, L., 30 Apr 2005, In : Fungal Genetics and Biology. 42, 4, p. 351-365 15 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)
2004

Genome sequence of the enterobacterial phytopathogen Erwinia carotovora subsp. atroseptica and characterization of virulence factors

Bell, K. S., Sebaihia, M., Pritchard, L., Holden, M. T. G., Hyman, L. J., Holeva, M. C., Thomson, N. R., Bentley, S. D., Churcher, L. J. C., Mungall, K., Atkin, R., Bason, N., Brooks, K., Chillingworth, T., Clark, K., Doggett, J., Fraser, A., Hance, Z., Hauser, H., Jagels, K. & 12 others, Moule, S., Norbertczak, H., Ormond, D., Price, C., Quail, M. A., Sanders, M., Walker, D., Whitehead, S., Salmond, G. P. C., Birch, P. R. J., Parkhill, J. & Toth, I. K., 27 Jul 2004, In : Proceedings of the National Academy of Sciences of the United States of America. 101, 30, p. 11105-11110 6 p.

Research output: Contribution to journalArticle

280 Citations (Scopus)
2003
3 Citations (Scopus)
2002

Schemes of flux control in a model of Saccharomyces cerevisiae glycolysis

Pritchard, L. & Kell, D. B., 31 Aug 2002, In : European Journal of Biochemistry . 269, 16, p. 3894-3904 11 p.

Research output: Contribution to journalArticle

79 Citations (Scopus)
2001

Evaluation of a novel method for the identification of coevolving protein residues

Pritchard, L., Bladon, P., Mitchell, J. M. O. & Dufton, M. J., 31 Aug 2001, In : Protein Engineering. 14, 6, p. 549-555 7 p.

Research output: Contribution to journalArticle

29 Citations (Scopus)
2000
16 Citations (Scopus)