Projects per year
Personal profile
Personal Statement
Please visit our group website: https://sipbs-compbiol.github.io/
Our group specialises in computational biology and bioinformatics, particularly for microbial genomics, but also in humans and plants. We have interests in taxonomy and classification of microbes, and the relationships between genome evolution and the different capabilities of organisms. We aim to understand links between genome and phenotype, such as the ability to produce - or resist - antibiotics, to produce enzymes and other products of biotechological value, the responses of human and plant cells to disease and infection, and the ways in which microbial pathogens interact with and control their hosts.
We study these areas using a range of techniques including phylogenetics and phylogenomics, comparative genomics and pangenomics, and mathematical and structural modelling.
You can follow the group (@SCompBiol), or me personally (@widdowquinn) on Twitter.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Bachelor of Arts, Mathematics, Open University
Bachelor of Science, Forensic and Analytical Chemistry, University Of Strathclyde
Doctor of Philosophy, Evolutionary analysis of protein sequence-structure-function relationships, University Of Strathclyde
External positions
Senior Editor, American Society for Microbiology
Keywords
- Computational Biology
- Bioinformatics
- Systems Biology
- Genomics
- Host-Microbe Interactions
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Collaborations and top research areas from the last five years
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BBSRC-NSF/BIO: Collaborative Proposal: genomeRxiv: a microbial whole-genome database and diagnostic marker design resource for classification, identification, and data sharing
Pritchard, L. (Principal Investigator)
BBSRC (Biotech & Biological Sciences Research Council)
8/03/21 → 28/03/25
Project: Research
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Targeted Innovation in the UK Seed Potato Industry to Improve Productivity and Quality
Pritchard, L. (Principal Investigator)
1/09/19 → 31/01/21
Project: Research
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The prevalence of Phytophthora in British plant nurseries: high-risk hosts and substrates and opportunities to influence practice
Green, S., Cooke, D. E. L., Barwell, L., Purse, B. V., Cock, P., Frederickson-Matika, D., Randall, E., Keillor, B., Pritchard, L., Thorpe, P., Pettit, T., Schlenzig, A. & Barbrook, J., 20 Jan 2025, (E-pub ahead of print) In: Plant Pathology. 22 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Downloads (Pure) -
LINgroups as a robust principled approach to compare and integrate multiple bacterial taxonomies
Mazloom, R., Pierce-Ward, N. T., Sharma, P., Pritchard, L., Brown, C. T., Vinatzer, B. A. & Heath, L. S., Nov 2024, In: IEEE/ACM Transactions on Computational Biology and Bioinformatics . 21, 6, p. 2304-2314 11 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile7 Downloads (Pure)
Datasets
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Supplementary Information for Kamat et al.
Pritchard, L. (Creator), Zenodo, 24 Jan 2024
DOI: 10.5281/zenodo.10560971, https://widdowquinn.github.io/SI_Kamat_et_al_Clostridium_diversity/
Dataset
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Data for: "16S rRNA phylogeny and clustering is not a reliable proxy for genome-based taxonomy in Streptomyces (raw data)"
Kiepas, A. (Creator), Hoskisson, P. (Creator) & Pritchard, L. (Creator), Zenodo, 26 Apr 2024
Dataset
Prizes
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2020 Metabolomics Publication Award
Mendez, K. (Recipient), Pritchard, L. (Recipient), Reinke, S. (Recipient) & Broadhurst, D. (Recipient), 11 Mar 2020
Prize: Prize (including medals and awards)
Activities
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PhD Committee - Virginia Tech
Pritchard, L. (Examiner)
31 Jan 2025Activity: Examination types › Examination
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Access Microbiology (Journal)
Pritchard, L. (Peer reviewer)
22 Aug 2024Activity: Publication peer-review and editorial work types › Journal peer review