If you made any changes in Pure these will be visible here soon.

Personal profile

Personal Statement

Research fellow - Cell signalling and Pharmacology.

I have been a researcher in the field of cell signalling and Pharmacology for over fourteen years specialising in the area of G-protein coupled receptors. My research area covers understanding the molecular mechanisims of GPCR signalling in the proccesses that underpin inflammation, with an emphasis on targert validation and drug discovery.  

I had the privilege of being part of a group which was one of the first to recognise the biological relevance of PAR2, developed one of the first PAR2 knockout models and indeed my research career started within the Ferrell and Lockhart group, who along with my current group, have forged a world lead in the area of chronic inflammation (arthritis). 


Education/Academic qualification

Doctor of Science, University of Paisley

1 Oct 200430 Sep 2008

Fingerprint Fingerprint is based on mining the text of the person's scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

  • 17 Similar Profiles
Proteinase-Activated Receptors Medicine & Life Sciences
PAR-2 Receptor Medicine & Life Sciences
Arthritis Medicine & Life Sciences
Phosphotransferases Medicine & Life Sciences
seryl-leucyl-isoleucyl--glycyl-lysyl-valine Medicine & Life Sciences
Mitogen-Activated Protein Kinase Phosphatases Medicine & Life Sciences
Purinergic Receptors Medicine & Life Sciences
JNK Mitogen-Activated Protein Kinases Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 2014 2020

Research Output 2007 2019

Novel protective role for MAP kinase phosphatase 2 in inflammatory arthritis

Schroeder, J., Ross, K., McIntosh, K., Jabbar, S. K. J., Woods, S., Crowe, J., Patterson-Kane, J. C., Alexander, J., Lawrence, C. & Plevin, R., 11 Jan 2019, 5, 1, p. e000711 9 p., e000711.

Research output: Contribution to journalArticle

Open Access
Mitogen-Activated Protein Kinase Phosphatases
Protein Phosphatase 2
Mitogen-Activated Protein Kinase 1
Phosphoric Monoester Hydrolases

Inhibition of cytokine-mediated JNK signalling by purinergic P2Y11 receptors, a novel protective mechanism in endothelial cells

Ng, P. Y., McIntosh, K. A., Hargrave, G., Ho, K. H., Paul, A. & Plevin, R., 30 Nov 2018, In : Cellular Signalling. 51, p. 59-71 13 p.

Research output: Contribution to journalArticle

Purinergic Receptors
JNK Mitogen-Activated Protein Kinases
Endothelial Cells
Adenine Nucleotides


Court Medal

Kathryn McIntosh (Recipient), 25 Jun 2003

Prize: Prize (including medals and awards)