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Personal profile

Personal Statement

Research fellow - Cell signalling and Pharmacology.

I have been a researcher in the field of cell signalling and Pharmacology for over fourteen years specialising in the area of G-protein coupled receptors. My research area covers understanding the molecular mechanisims of GPCR signalling in the proccesses that underpin inflammation, with an emphasis on targert validation and drug discovery.  

I had the privilege of being part of a group which was one of the first to recognise the biological relevance of PAR2, developed one of the first PAR2 knockout models and indeed my research career started within the Ferrell and Lockhart group, who along with my current group, have forged a world lead in the area of chronic inflammation (arthritis). 

 

Education/Academic qualification

Doctor of Science, University of Paisley

1 Oct 200430 Sep 2008

Fingerprint Fingerprint is based on mining the text of the person's scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

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Projects 2018 2020

Research Output 2007 2018

Purinergic Receptors
JNK Mitogen-Activated Protein Kinases
Endothelial Cells
Cytokines
Adenine Nucleotides
2 Citations

Inhibitory Kappa B kinase α (IKKα) inhibitors that recapitulate their selectivity in cells against isoform-related biomarkers

Anthony, N. G. , Baiget, J. , Berretta, G. , Boyd, M. , Breen, D. , Edwards, J. , Gamble, C. , Gray, A. I. , Harvey, A. L. , Hatziieremia, S. , Ho, K. H. , Huggan, J. K. , Lang, S. , Llona-Minguez, S. , Luo, J. L. , McIntosh, K. , Paul, A. , Plevin, R. J. , Robertson, M. N. , Scott, R. & 4 others Suckling, C. J., Sutcliffe, O. B., Young, L. C. & MacKay, S. P., 24 Jul 2017, In : Journal of Medicinal Chemistry. 60, 16, p. 7043-7066 24 p.

Research output: Contribution to journalArticle

Open Access
File
Protein Isoforms
Phosphotransferases
Biomarkers
NF-kappa B
Phosphorylation

Prizes

Court Medal

Kathryn McIntosh (Recipient), 25 Jun 2003

Prize: Prize (including medals and awards)

student