My main research background concerns studies on the influence of magnetic nanoparticles on magnetic, ultrasonic, and magneto-ultrasonic heating performed on tissue-mimicking phantoms.
The scientific work addressed the following questions:
*how the presence of magnetic nanoparticles in tissue-mimicking phantoms affects the acoustical properties (e.g., acoustic velocity, attenuation coefficient) of phantoms;
*how the type of magnetic doping material used (suspension, powder, nanospheres, and clusters) influences the effectiveness of magnetic and ultrasonic heating;
*how the mechanical properties (e.g., compressibility) of tissue-mimicking phantoms influence the thermal effect of magnetic hyperthermia.
*how the magnetic nanoparticles influence temperature increase in tissue-mimicking materials during focused and non-focused ultrasound heating.
The main results of this research show that the use of magnetic nanoparticles in ultrasound and magnetic heating was found to be beneficial. Their presence in tissue-mimicking phantoms led to the improvement of applied thermal therapies. The most promising result was observed during the combined irradiation of the focused ultrasound and alternating magnetic field. The observed temperature rise during this bimodal treatment exceeded the thermal effects achieved with single heating components. All of this work is expected to broaden understanding and current knowledge of the influence of nanomaterials on the effectiveness of currently popular thermal therapies. It might also lead to consideration of magneto- ultrasonic heating as a possible innovative thermal therapy.
Currently, I am working with an excellent scientist on the development of elasticity imaging using contrast-enhanced magneto-motive ultrasound (CE-MMUS) for the early detection of colorectal cancer. An innovative study that combines the use of ultrasounds, superparamagnetic iron-oxide nanoparticles and microbubbles.