Photo of Katarzyna Kaczmarek

Katarzyna Kaczmarek

Dr

  • United Kingdom

20162020

Research output per year

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Personal profile

Personal Statement

My main research background concerns studies on the influence of magnetic nanoparticles on magnetic, ultrasonic, and magneto-ultrasonic heating performed on tissue-mimicking phantoms.
 
The scientific work addressed the following questions:
*how the presence of magnetic nanoparticles in tissue-mimicking phantoms affects the acoustical properties (e.g., acoustic velocity, attenuation coefficient) of phantoms;
 *how the type of magnetic doping material used (suspension, powder, nanospheres, and clusters) influences the effectiveness of magnetic and ultrasonic heating;
*how the mechanical properties (e.g., compressibility) of tissue-mimicking phantoms influence the thermal effect of magnetic hyperthermia.
*how the magnetic nanoparticles influence temperature increase in tissue-mimicking materials during focused and non-focused ultrasound heating.
 
The main results of this research show that the use of magnetic nanoparticles in ultrasound and magnetic heating was found to be beneficial. Their presence in tissue-mimicking phantoms led to the improvement of applied thermal therapies. The most promising result was observed during the combined irradiation of the focused ultrasound and alternating magnetic field. The observed temperature rise during this bimodal treatment exceeded the thermal effects achieved with single heating components. All of this work is expected to broaden understanding and current knowledge of the influence of nanomaterials on the effectiveness of currently popular thermal therapies. It might also lead to consideration of magneto- ultrasonic heating as a possible innovative thermal therapy.
 
Currently, I am working with an excellent scientist on the development of elasticity imaging using contrast-enhanced magneto-motive ultrasound (CE-MMUS) for the early detection of colorectal cancer. An innovative study that combines the use of ultrasounds, superparamagnetic iron-oxide nanoparticles and microbubbles. 

Education/Academic qualification

Doctor of Science, Adam Mickiewicz University

20162019

Master in Science, Adam Mickiewicz University

20142016

Bachelor of Science, Adam Mickiewicz University

20112014

Bachelor of Science, Adam Mickiewicz University

20102013

Keywords

  • magnetic nanoparticles
  • magnetic hyperthermia
  • ultrasonic hyperthermia
  • Ultrasound
  • focused ultrasound
  • magnetism
  • Ultrasonics
  • tissue mimicking materials
  • theranostics
  • anticancer treatment
  • medical ultrasound
  • microbubbles
  • ultrasound, imaging, microbubbles, elastography, tissue mechanics
  • nanomaterials
  • acoustics

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Research Output

The influence of magnetic nanoparticle concentration with dextran polymers in agar gel on heating efficiency in magnetic hyperthermia

Skumiel, A., Kaczmarek, K., Flak, D., Rajnak, M., Antal, I. & Brząkała, H., 19 Feb 2020, In : Journal of Molecular Liquids. 304, 6 p., 112734.

Research output: Contribution to journalArticle

Open Access
File
  • Magneto-ultrasonic heating with nanoparticles

    Kaczmarek, K., Hornowski, T., Anta, I., Timko, M. & Józefczak, A., 15 Mar 2019, In : Journal of Magnetism and Magnetic Materials . 474, p. 400-405 6 p.

    Research output: Contribution to journalArticle

  • 8 Citations (Scopus)