Karen Faulds — University of Strathclyde

Personal profile

Research Interests

Our research focuses on using surface enhanced Raman scattering (SERS) to create new approaches to bioanalysis for use in the life and clinical sciences. SERS is a spectroscopic technique that offers significant advantages over other established techniques such as fluorescence and our research has focused on highlighting the advantages, creating new examples of increased capability in life science applications and interacting with end users to shape future step changes in research. Our research centres around using the inherent sensitivity of SERS for the detection of target DNA or proteins using signal amplification methods to enhance the signal rather than using target amplification methods such as PCR. Our work has focussed on exploiting the sensitivity of SERS for quantitative analysis of biomolecules as well as exploiting one of the key advantages of SERS, the ability to analyse multiple analytes in one sample. This allows more information to be gained per analysis as well as giving information about complex systems that are intrinsically difficult to measure.

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Projects 2006 2023

1 Not started
18 Active
42 Finished

EPSRC i-sense IRC: Ultra-Sensitive Enhanced NanoSensing of Anti-Microbial Resistance (u-Sense)

Graham, D. & Faulds, K.

EPSRC (Engineering and Physical Sciences Research Council)

1/10/18 → 31/08/22

Project: Research

Catching Nucleation in Action with Surface Enhanced Raman Spectroscopy

Johnston, K. & Faulds, K.

Carnegie Trust for the Universities of Scotland

1/09/18 → 1/08/19

Project: Research

Research Output 2002 2018

4159 Citations
129 Article
6 Conference contribution
4 Chapter (peer-reviewed)
4 Comment/debate
12 More

Bayesian modelling and quantification of Raman spectroscopy

Moores, M., Gracie, K., Carson, J., Faulds, K., Graham, D. & Girolami, M. 24 Jan 2018 (Accepted/In press) In : Annals of Applied Statistics.

Research output: Contribution to journal › Article

Open Access

File

Bayesian Modeling

Raman Spectrum Analysis

Raman Spectroscopy

Quantification

Raman spectroscopy

2 Citations

Development of a label-free Raman imaging technique for differentiation of malaria parasite infected from non-infected tissue

Frame, L., Brewer, J., Lee, R., Faulds, K. & Graham, D. 7 Jan 2018 In : Analyst. 143, 1, p. 157-163 7 p.

Research output: Contribution to journal › Article

malaria

Malaria

Labels

parasite

Parasites

Datasets

Data for: "Towards establishing a minimal nanoparticle concentration for applications involving surface enhanced spatially offset Raman spectroscopy (SESORS) in vivo"

Nicolson, F. (Creator), Jamieson, L. (Creator), Mabbott, S. (Creator), Plakas, K. (Creator), Shand, N. (Creator), Detty, M. R. (Creator), Graham, D. (Creator), Faulds, K. (Creator), University of Strathclyde, 5 Oct 2018

DOI: 10.15129/d594ff1c-9d11-4e6b-aeea-78c8a1864499

Dataset