Karen Faulds

Personal profile

Research Interests

Our research focuses on using surface enhanced Raman scattering (SERS) to create new approaches to bioanalysis for use in the life and clinical sciences. SERS is a spectroscopic technique that offers significant advantages over other established techniques such as fluorescence and our research has focused on highlighting the advantages, creating new examples of increased capability in life science applications and interacting with end users to shape future step changes in research. Our research centres around using the inherent sensitivity of SERS for the detection of target DNA or proteins using signal amplification methods to enhance the signal rather than using target amplification methods such as PCR. Our work has focussed on exploiting the sensitivity of SERS for quantitative analysis of biomolecules as well as exploiting one of the key advantages of SERS, the ability to analyse multiple analytes in one sample. This allows more information to be gained per analysis as well as giving information about complex systems that are intrinsically difficult to measure.

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Projects 2006 2023

1 Not started
17 Active
54 Finished

Catching nucleation in action using surface enhanced Raman spectroscopy

Johnston, K., Faulds, K. & Sefcik, J.

Leverhulme Trust

1/02/20 → 31/01/23

Project: Research

Doctoral Training Partnership 2018-19 University of Strathclyde | Buchanan, Craig

Graham, D., Faulds, K. & Buchanan, C.

EPSRC (Engineering and Physical Sciences Research Council)

1/10/19 → 1/04/23

Project: Research Studentship - Internally Allocated

Research Output 2002 2020

136 Article
6 Conference contribution book
4 Chapter (peer-reviewed)
4 Comment/debate
14 More

Detection of multiple nitroaromatic explosives via formation of a Janowsky complex and SERS

Milligan, K., Shand, N. C., Graham, D. & Faulds, K., 13 Jan 2020, In : Analytical Chemistry. 9 p.

Research output: Contribution to journal › Article

Open Access

File

Raman scattering

Mass spectrometry

Trinitrotoluene

Ions

Liquid chromatography

DNA detection by SERS: hybridisation parameters and the potential for asymmetric PCR

Macdonald, D., Smith, E., Faulds, K. & Graham, D., 13 Jan 2020, In : Analyst. 7 p.

Research output: Contribution to journal › Article

Raman Spectrum Analysis

Scattering parameters

Raman scattering

DNA

scattering

Datasets

Data for: "Detection of multiple nitroaromatic explosives via formation of a Janowsky complex and SERS"

Milligan, K. (Creator), University of Strathclyde, 31 Jan 2020

DOI: 10.15129/4f8897b7-23b6-42ae-b4c0-736fe3e994b2

Dataset

Data for: "Towards establishing a minimal nanoparticle concentration for applications involving surface enhanced spatially offset Raman spectroscopy (SESORS) in vivo"

Nicolson, F. (Creator), Jamieson, L. (Creator), Mabbott, S. (Creator), Plakas, K. (Creator), Shand, N. (Creator), Detty, M. R. (Creator), Graham, D. (Creator), Faulds, K. (Creator), University of Strathclyde, 5 Oct 2018

DOI: 10.15129/d594ff1c-9d11-4e6b-aeea-78c8a1864499

Dataset