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Personal profile

Research Interests

Our research focuses on using surface enhanced Raman scattering (SERS) to create new approaches to bioanalysis for use in the life and clinical sciences.  SERS is a spectroscopic technique that offers significant advantages over other established techniques such as fluorescence and our research has focused on highlighting the advantages, creating new examples of increased capability in life science applications and interacting with end users to shape future step changes in research.  Our research centres around using the inherent sensitivity of SERS for the detection of target DNA or proteins using signal amplification methods to enhance the signal rather than using target amplification methods such as PCR.  Our work has focussed on exploiting the sensitivity of SERS for quantitative analysis of biomolecules as well as exploiting one of the key advantages of SERS, the ability to analyse multiple analytes in one sample.  This allows more information to be gained per analysis as well as giving information about complex systems that are intrinsically difficult to measure.

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Raman scattering Chemical Compounds
Raman Spectrum Analysis Medicine & Life Sciences
Nanoparticles Chemical Compounds
Raman spectroscopy Chemical Compounds
Gold Chemical Compounds
DNA Chemical Compounds
Silver Chemical Compounds
Coloring Agents Chemical Compounds

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Projects 2006 2023

Research Output 2002 2020

Open Access
Raman scattering
Mass spectrometry
Liquid chromatography

DNA detection by SERS: hybridisation parameters and the potential for asymmetric PCR

Macdonald, D., Smith, E., Faulds, K. & Graham, D., 13 Jan 2020, In : Analyst. 7 p.

Research output: Contribution to journalArticle

Raman Spectrum Analysis
Scattering parameters
Raman scattering


Awarded Fellow of Royal Society of Chemistry (FRSC)

Karen Faulds (Recipient), 2012

Prize: Fellowship awarded competitively

Charles Mann Award

Karen Faulds (Recipient), Oct 2019

Prize: Prize (including medals and awards)

Activities 2008 2019

SciX 2019

Karen Faulds (Invited speaker)
Oct 2019

Activity: Talk or presentation typesInvited talk

SciX 2019

Karen Faulds (Keynote/plenary speaker)
Oct 2019

Activity: Participating in or organising an event typesKey-note speaker and plenary lectures at conferences


Multiple target molecular diagnostics testing provides better diagnostics for healthcare

Duncan Graham (Participant), W. Ewen Smith (Participant), Karen Faulds (Participant)

Impact: Impact - for External PortalEconomic and commerce, Health and welfare - new products, guidelines and services