Judith Pratt

Prof

  • United Kingdom

Accepting PhD Students

20012020

Research output per year

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Research Output

Article

[DELTA]9-tetrahydrocannabinol-induced alterations in limbic system glucose use in the rat

Brett, R., MacKenzie, F. & Pratt, J., 16 Nov 2001, In : NeuroReport. 12, 16, p. 3573-3577 4 p.

Research output: Contribution to journalArticle

Acute ∆9-tetrahydrocannabinol-induced deficits in reversal learning: neural correlates of affective inflexibility

Egerton, A. D., Brett, R. R. & Pratt, J. A., 6 Apr 2005, In : Neuropsychopharmacology. 30, p. 1895-1905 11 p.

Research output: Contribution to journalArticle

38 Citations (Scopus)

Altered functional brain network connectivity and glutamate system function in transgenic mice expressing truncated Disrupted-in-Schizophrenia 1

Dawson, N., Kurihara, M., Thomson, DM., Winchester, CL., McVie, A., Hedde, JR., Randall, AD., Shen, S., Seymour, PA., Hughes, ZA., Dunlop, J., Brown, JT., Brandon, NJ., Morris, BJ. & Pratt, JA., 19 May 2015, In : Translational Psychiatry. 5, 12 p., e569.

Research output: Contribution to journalArticle

Open Access
File
23 Citations (Scopus)
43 Downloads (Pure)

Alternating hemiplegia of childhood-related neural and behavioural phenotypes in Na+,K+-ATPase α3 missense mutant mice

Kirshenbaum, G. S., Dawson, N., Mullins, J. G. L., Johnston, T. H., Drinkhill, M. J., Edwards, I. J., Fox, S. H., Pratt, J. A., Brotchie, J. M., Roder, J. C. & Clapcote, S. J., 20 Mar 2013, In : PLoS ONE. 8, 3, 15 p., e60141.

Research output: Contribution to journalArticle

32 Citations (Scopus)

AMPA receptor autoradiography in mouse brain following single and repeated withdrawal from diazepam

Allison, C., Pratt, J. A., Ripley, T. & Stephens, D. N., 2005, In : European Journal of Neuroscience. 21, p. 1045-1056 11 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Cannabidiol inhibits synaptic transmission in rat hippocampal cultures and slices via multiple receptor pathways

Ledgerwood, C., Greenwood, S. M., Brett, R. R., Pratt, J. A. & Bushell, T., Jan 2011, In : British Journal of Pharmacology. 162, 1, p. 286-294 9 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Cannabinoids and prefrontal cortical function: insights from preclinical studies

Egerton, A. D., Allison, C., Brett, R. R. & Pratt, J. A., 2006, In : Neuroscience and Biobehavioral Reviews. 30, 5, p. 680-695 16 p.

Research output: Contribution to journalArticle

107 Citations (Scopus)

Chronic phencyclidine (PCP)-induced modulation of muscarinic receptor mRNAs in rat brain: impact of antipsychotic drug treatment

Steward, L. J., Kennedy, M. D., Morris, B. J. & Pratt, J. A., Mar 2012, In : Neuropharmacology. 62, 3, p. 1554-1563 10 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Clozapine produces modest effects on pcp-induced performance deficits in the 5-choice serial reaction time task

Thomson, D. M., Mcvie, A., Morris, B. J. & Pratt, J. A., Sep 2008, In : Behavioural Pharmacology. 19, 5-6, p. 655-656 1 p.

Research output: Contribution to journalArticle

Converging evidence that sequence variations in the novel candidate gene MAP2K7 (MKK7) are functionally associated with schizophrenia

Winchester, C., Ohzeki, H., Vouyiouklis, D., Thompson, R., Yamagami, K., Norrie, J., Hunter, R., Pratt, J. & Morris, B. J., 15 Nov 2012, In : Human Molecular Genetics . 21, 22, p. 4910-4921 12 p.

Research output: Contribution to journalArticle

25 Citations (Scopus)
10 Citations (Scopus)

Differential effects of two chronic diazepam treatment regimes on withdrawal anxiety and aMPA receptor characteristics

Allison, C. & Pratt, J. A., Jun 2006, In : Neuropsychopharmacology. 31, p. 602-619 18 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)

Disruption of the Zdhhc9 intellectual disability gene leads to behavioural abnormalities in a mouse

Kouskou, M., Thomson, D. M., Brett, R. R., Wheeler, L., Tate, R. J., Pratt, J. A. & Chamberlain, L. H., 31 Oct 2018, In : Experimental Neurology. 308, p. 35-46 12 p.

Research output: Contribution to journalArticle

Open Access
File
2 Citations (Scopus)
27 Downloads (Pure)

Dissociation of acute and chronic intermittent phencyclidine-induced performance deficits in the 5-choice serial reaction time task: influence of clozapine

Thomson, D. M., McVie, A., Morris, B. J. & Pratt, J. A., 2011, In : Psychopharmacology. 213, 4, p. 681-95 15 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)
Open Access
File
2 Downloads (Pure)

Exploring metabolic pathway disruption in the subchronic phencyclidine model of schizophrenia with the generalized singular value decomposition

Xiao, X., Dawson, N., MacIntyre, L., Morris, B. J., Pratt, J. A., Watson, D. G. & Higham, D. J., 16 May 2011, In : BMC Systems Biology. 5, 20 p., 72.

Research output: Contribution to journalArticle

Open Access
File
15 Citations (Scopus)
76 Downloads (Pure)

Functional brain connectivity phenotypes for schizophrenia drug discovery

Dawson, N., Morris, B. J. & Pratt, J. A., 1 Feb 2015, In : Journal of Psychopharmacology. 29, 2, p. 169-177 9 p.

Research output: Contribution to journalArticle

Open Access
File
15 Citations (Scopus)
68 Downloads (Pure)

Impairment in perceptual attentional set shifting following PCP administration: a rodent model of set-shifting deficits in schizophrenia

Egerton, A. D., Reid, L., McKerchar, C., Morris, B. J. & Pratt, J. A., 2005, In : Psychopharmacology. 179, p. 77-84 8 p.

Research output: Contribution to journalArticle

112 Citations (Scopus)

Induction of metabolic hypofunction and neurochemical deficits after chronic intermittent exposure to phencyclidine: differential modulation by antipsychotic drugs

Cochran, S. M., Steward, L., Kennedy, M. D., McKerchar, C., Pratt, J. A. & Morris, B. J., 2003, In : Neuropsychopharmacology. 28, p. 265-275 11 p.

Research output: Contribution to journalArticle

184 Citations (Scopus)

JNK signalling mediates aspects of maternal immune activation: importance of maternal genotype in relation to schizophrenia risk

Openshaw, R. L., Kwon, J., McColl, A., Penninger, J. M., Cavanagh, J., Pratt, J. A. & Morris, B. J., 28 Jan 2019, In : Journal of Neuroinflammation. 16, 1, 11 p., 18.

Research output: Contribution to journalArticle

Open Access
File
3 Citations (Scopus)
9 Downloads (Pure)

M4 agonists/5HT7 antagonists with potential as antischizophrenic drugs: serominic compounds

Suckling, C. J., Murphy, J. A., Khalaf, A. I., Zhou, S., Lizos, D. E., Nguyen Van Nhien, A., Yasumatsu, H., McVie, A., Young, L. C., McCraw, C., Waterman, P. G., Morris, B. J., Pratt, J. A. & Harvey, A., 1 May 2007, In : Bioorganic and Medicinal Chemistry Letters. 17, 9, p. 2649-2655 7 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)

Map2k7 haploinsufficiency induces brain imaging endophenotypes and behavioral phenotypes relevant to schizophrenia

Openshaw, R. L., Thomson, D. M., Thompson, R., Penninger, J. M., Pratt, J. A., Morris, B. J. & Dawson, N., 4 Jan 2020, In : Schizophrenia Bulletin. 46, 1, p. 211-223 13 p.

Research output: Contribution to journalArticle

Open Access
File
1 Downloads (Pure)
Open Access
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5 Citations (Scopus)
56 Downloads (Pure)

Miniature wireless recording and stimulation system for rodent behavioural testing

Pinnell, R. C., Dempster, J. & Pratt, J., 19 Oct 2015, In : Journal of Neural Engineering. 12, 6, 15 p., 066015.

Research output: Contribution to journalArticle

Open Access
File
12 Citations (Scopus)
94 Downloads (Pure)

Modafinil reverses phencyclidine-induced deficits in cognitive flexibility, cerebral metabolism, and functional brain connectivity

Dawson, N., Thompson, R. J., McVie, A., Thomson, D. M., Morris, B. J. & Pratt, J., 3 May 2012, In : Schizophrenia Bulletin. 38, 3, p. 457-474 18 p.

Research output: Contribution to journalArticle

35 Citations (Scopus)

Modelling prefrontal cortex deficits in schizophrenia: implications for treatment

Pratt, J. A., Winchester, C., Egerton, A., Cochran, S. M. & Morris, B. J., Mar 2008, In : British Journal of Pharmacology. 153, p. S465-S470

Research output: Contribution to journalArticle

114 Citations (Scopus)

Neuropsychiatric disease and toxoplasma gondii infection

Henriquez, S. A., Brett, R., Alexander, J., Pratt, J. & Roberts, C. W., 2009, In : Neuroimmunomodulation. 16, 2, p. 122-133 12 p.

Research output: Contribution to journalArticle

116 Citations (Scopus)
2 Citations (Scopus)

Regulation of hippocampal cannabinoid CB1 receptor actions by adenosine A1 receptors and chronic caffeine administration: implications for the effects of Δ9-tetrahydrocannabinol on spatial memory

Sousa, V. C., Assaife-Lopes, N., Ribeiro, J. A., Pratt, J. A., Brett, R. R. & Sebastião, A. M., 2011, In : Neuropsychopharmacology . 36, 2, p. 472-487 16 p.

Research output: Contribution to journalArticle

36 Citations (Scopus)

Risk genes for schizophrenia: translational opportunities for drug discovery

Winchester, C. L., Pratt, J. A. & Morris, B. J., Jul 2014, In : Pharmacology and Therapeutics. 143, 1, p. 34-50 17 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)

Subanaesthetic ketamine treatment alters prefrontal cortex connectivity with thalamus and ascending subcortical systems

Dawson, N., Morris, B. J. & Pratt, J., 2 Mar 2013, In : Schizophrenia Bulletin. 39, 2, p. 366-377 12 p.

Research output: Contribution to journalArticle

45 Citations (Scopus)
22 Citations (Scopus)

Subchronic and chronic PCP treatment produces temporally distinct deficits in attentional set shifting and prepulse inhibition in rats

Egerton, A., Reid, L., McGregor, S., Cochran, S. M., Morris, B. J. & Pratt, J., Apr 2008, In : Psychopharmacology. 198, 1, p. 37-49 13 p.

Research output: Contribution to journalArticle

88 Citations (Scopus)

Sustained NMDA receptor hypofunction induces compromised neural systems integration and schizophrenia-like alterations in functional brain networks

Dawson, N., Xiao, X., McDonald, M. D., Higham, D., Morris, B. J. & Pratt, J., Feb 2014, In : Cerebral Cortex. 24, 2, p. 452-464 13 p.

Research output: Contribution to journalArticle

27 Citations (Scopus)

Thalamo-cortical communication, glutamatergic neurotransmission and neural oscillations: a unique window into the origins of ScZ?

Pratt, J., Dawson, N., Morris, B. J., Grent T'Jong, T., Roux, F. & Uhlhaas, P. J., Feb 2017, In : Schizophrenia Research. 180, p. 4-12 9 p.

Research output: Contribution to journalArticle

Open Access
File
14 Citations (Scopus)
61 Downloads (Pure)
Open Access
File
32 Citations (Scopus)
60 Downloads (Pure)

Viral-mediated knockdown of ERBB4 in the rodent prefrontal cortex enhances cognitive performance

Winchester, C. L., Paterson, C., Morris, B., Glover, C. P., Storey, J., Hussein, I. & Pratt, J. A., Aug 2011, In : Journal of Psychopharmacology. 25, 8 Supplement S, p. A68-A68 1 p.

Research output: Contribution to journalArticle

Chapter

Biomarkers in neuropsychiatry: a prospect for the twenty-first century?

Pratt, J. & Hall, J., 3 Jul 2018, Current Topics in Behavioral Neurosciences. Berlin: Springer, 8 p. (Current Topics in Behavioral Neurosciences).

Research output: Chapter in Book/Report/Conference proceedingChapter

7 Citations (Scopus)

Deconstructing schizophrenia: advances in preclinical models for biomarker identification

Pratt, J. A., Morris, B. & Dawson, N., 3 May 2018, Current Topics in Behavioral Neurosciences. Berlin: Springer, 29 p. (Current Topics in Behavioral Neurosciences).

Research output: Chapter in Book/Report/Conference proceedingChapter

4 Citations (Scopus)
Conference Contribution

Alterations in functional brain network structure induced by subchronic phencyclidine (PCP) treatment parallel those seen in schizophrenia

Dawson, N., Higham, D., Pratt, J. & Morris, B., Apr 2010, In : Schizophrenia Research. 117, 2-3, p. 234-235 2 p.

Research output: Contribution to journalConference Contribution

File
163 Downloads (Pure)

Is there a relationship between toxoplasma gondii and psychiatric disorders?

Henriquez, S. A., Thompson, D. M., Henriquez, F. L., Alexander, J., Pratt, J., Brett, R. & Roberts, C. W., Apr 2010, In : Schizophrenia Research. 117, 2-3, p. 389-390 2 p.

Research output: Contribution to journalConference Contribution

Editorial
Open Access
File
2 Citations (Scopus)
20 Downloads (Pure)
Literature review

Advancing schizophrenia drug discovery: optimizing rodent models to bridge the translational gap

Pratt, J., Winchester, C., Dawson, N. & Morris, B., Jul 2012, In : Nature Reviews Drug Discovery . 11, 7, p. 560-579 20 p.

Research output: Contribution to journalLiterature review

95 Citations (Scopus)
18 Downloads (Pure)

Novel treatment strategies for schizophrenia from improved understanding of genetic risk

Morris, B. J. & Pratt, J. A., Nov 2014, In : Clinical Genetics. 86, 5, p. 401-411 11 p.

Research output: Contribution to journalLiterature review

Open Access
File
11 Citations (Scopus)
150 Downloads (Pure)
Meeting abstract

Environment-environment interactions in a schizophrenia-related disease model: impact of poly ic and thc on the developing brain

Stenson, G. S., Pratt, J. & Brett, R., Aug 2011, In : Journal of Psychopharmacology. 25, 8 Supplement S, p. A68-A68 1 p.

Research output: Contribution to journalMeeting abstract

Impact of modafinil on acquisition and subsequent performance of pcp -treated rats in the 5 -choice serial reaction time task

Davies, C. L., Thomson, D. M., Morris, B. J. & Pratt, J. A., Aug 2011, In : Journal of Psychopharmacology. 25, 8 Supplement S, p. A71-A71 1 p.

Research output: Contribution to journalMeeting abstract

2 Citations (Scopus)

Subanaesthetic ketamine treatment alters prefrontal cortex functional connectivity and the properties of functional brain networks

Dawson, N., McDonald, M., Higham, D. J., Morris, B. J. & Pratt, J. A., Aug 2011, In : Journal of Psychopharmacology. 25, 8, p. A63-A63 1 p.

Research output: Contribution to journalMeeting abstract

Using next generation sequencing to investigate DPYSL2 gene variants in schizophrenia

Winchester, C. L., Hamilton, G. M., Morris, B., Pratt, J. A., Hunter, R. & Bailey, M. E. S., Aug 2011, In : Journal of Psychopharmacology. 25, 8 Supplement S, p. A67-A67 1 p.

Research output: Contribution to journalMeeting abstract

Paper

Exposure of cultured hippocampal neurones to cannabidiol does not induce cell death but inhibits synaptic activity

Brett, R. R., Pratt, J. A., Bushell, T. & Ledgerwood, C., Jun 2008, (Unpublished).

Research output: Contribution to conferencePaper