20132023

Research output per year

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Research Output

2020

Nucleation control in continuous crystallization

Sefcik, J., Ter Horst, J., McGinty, J. & Price, C. J., 21 Feb 2020, The Handbook of Continuous Crystallization. Yazdanpanah, N. & Nagy, Z. (eds.). 1st ed. [S.I.]: Royal Society of Chemistry

Research output: Chapter in Book/Report/Conference proceedingChapter

On the effect of secondary nucleation on deracemization through temperature cycles

Cameli, F., ter Horst, J. H., Steendam, R. R. E., Xiouras, C. & Stefanidis, G. D., 27 Jan 2020, In : Chemistry - A European Journal . 26, 6, p. 1344-1354 11 p.

Research output: Contribution to journalArticle

2019

Measuring secondary nucleation through single crystal seeding

Briuglia, M. L., Sefcik, J. & Horst, J. H. T., 2 Jan 2019, In : Crystal Growth and Design. 19, 1, p. 421-429 9 p.

Research output: Contribution to journalArticle

Open Access
File
4 Citations (Scopus)
5 Downloads (Pure)

Paracetamol habit modification by impurities

Urwin, S., Martin, A. & Ter Horst, J., 9 Jul 2019. 1 p.

Research output: Contribution to conferencePoster

Open Access
File
8 Downloads (Pure)
Open Access
File
17 Citations (Scopus)
1 Downloads (Pure)
Open Access
File
1 Citation (Scopus)
6 Downloads (Pure)

Towards continuous deracemization via racemic crystal transformation monitored by in-situ Raman spectroscopy

Xiouras, C., Belletti, G., Venkatramanan, R., Nordon, A., Meekes, H., Vlieg, E., Stefanidis, G. D. & Ter Horst, J. H., 2 Oct 2019, In : Crystal Growth and Design. 19, 10, p. 5858-5868 11 p.

Research output: Contribution to journalArticle

Open Access
File
2 Downloads (Pure)
2018

Enabling precision manufacturing of active pharmaceutical ingredients: workflow for seeded cooling continuous crystallisations

Brown, C. J., McGlone, T., Yerdelen, S., Srirambhatla, V., Mabbott, F., Gurung, R., Briuglia, M. L., Ahmed, B., Polyzois, H., McGinty, J., Perciballi, F., Fysikopoulos, D., Macfhionnghaile, P., Siddique, H., Raval, V., Harrington, T. S., Vassileiou, A. D., Robertson, M., Prasad, E., Johnston, A. & 9 others, Johnston, B., Nordon, A., Srai, J. S., Halbert, G., ter Horst, J. H., Price, C. J., Rielly, C. D., Sefcik, J. & Florence, A. J., 1 Jun 2018, In : Molecular Systems Design & Engineering. 2018, 3, p. 518-549 32 p.

Research output: Contribution to journalArticle

Open Access
File
18 Citations (Scopus)
66 Downloads (Pure)

Particle breakage kinetics and mechanisms in attrition-enhanced deracemization

Xiouras, C., Fytopoulos, A. A., Ter Horst, J. H., Boudouvis, A. G., Van Gerven, T. & Stefanidis, G. D., 2 May 2018, In : Crystal Growth and Design. 18, 5, p. 3051-3061 11 p.

Research output: Contribution to journalArticle

Open Access
File
8 Citations (Scopus)
18 Downloads (Pure)

Particle size distributions and performance of preferential crystallization of L-asparagine·H2O with tailor-made additives

Kongsamai, P., Flood, C., ter Horst, J. H. & Flood, A. E., 24 Mar 2018, In : Chemical Engineering and Technology. 27 p.

Research output: Contribution to journalArticle

Open Access
File
2 Citations (Scopus)
16 Downloads (Pure)

Scaling up temperature cycling-induced deracemization by suppressing nonstereoselective processes

Steendam, R. R. E. & ter Horst, J. H., 2 May 2018, In : Crystal Growth and Design. 18, 5, p. 3008-3015 8 p.

Research output: Contribution to journalArticle

Open Access
File
6 Citations (Scopus)
13 Downloads (Pure)
2017

Continuous total spontaneous resolution

Steendam, R. R. E. & Ter Horst, J. H., 3 Jul 2017, In : Crystal Growth and Design . 17, 8, p. 4428-4436 9 p.

Research output: Contribution to journalArticle

Open Access
File
9 Citations (Scopus)
12 Downloads (Pure)

Coupling Viedma ripening with racemic crystal transformations: mechanism of deracemization

Xiouras, C., Ter Horst, J. H., Van Gerven, T. & Stefanidis, G. D., 6 Sep 2017, In : Crystal Growth and Design. 17, 9, p. 4965-4976 12 p.

Research output: Contribution to journalArticle

Open Access
File
13 Citations (Scopus)
14 Downloads (Pure)

Effect of additives on the preferential crystallization of L-asparagine monohydrate

Kongsamai, P., Maneedaeng, A., Flood, C., ter Horst, J. H. & Flood, A. E., 18 Apr 2017, In : European Physical Journal: Special Topics. 226, 5, p. 823-835 13 p.

Research output: Contribution to journalArticle

Open Access
File
5 Citations (Scopus)
29 Downloads (Pure)

Immobilization of gluten in spherical matrices of food-grade hydrogels

Reus, M. A., Krintiras, G. A., Stefanidis, G. D., ter Horst, J. H. & van der Heijden, A. E. D. M., 24 Jan 2017, In : Journal of Food Process Engineering.

Research output: Contribution to journalArticle

Open Access
File
18 Downloads (Pure)

Solution co-crystallisation and its applications

Leyssens, T. & ter Horst, J. H., 23 Nov 2017, Multi-Component Crystals: Synthesis, Concepts, Function. Tiekink, E. R. T. & Zukerman-Schpector, J. (eds.). Berlin: Walter de Gruyter GmbH, p. 205-236 32 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

4 Citations (Scopus)

Towards deracemization in the absence of grinding through crystal transformation, ripening, and racemization

Xiouras, C., Van Cleemput, E., Kumpen, A., Ter Horst, J. H., Van Gerven, T. & Stefanidis, G. D., 1 Feb 2017, In : Crystal Growth and Design . 17, 2, p. 882-890 9 p.

Research output: Contribution to journalArticle

Open Access
File
10 Citations (Scopus)
21 Downloads (Pure)
2016

Co-crystals of diflunisal and isomeric pyridinecarboxamides – a thermodynamics and crystal engineering contribution

Évora, A. O. L., Castro, R. A. E., Maria, T. M. R., Silva, M. R., ter Horst, J. H., Canotilho, J. & Eusébio, M. E. S., 5 May 2016, In : CrystEngComm. 18, 25, p. 4749-4759 11 p.

Research output: Contribution to journalArticle

Open Access
File
7 Citations (Scopus)
32 Downloads (Pure)

Deracemization of a racemic compound via its conglomerate-forming salt using temperature cycling

Li, W. W., Spix, L., De Reus, S. C. A., Meekes, H., Kramer, H. J. M., Vlieg, E. & ter Horst, J. H., 7 Sep 2016, In : Crystal Growth and Design . 16, 9, p. 5563-5570 8 p.

Research output: Contribution to journalArticle

Open Access
File
20 Citations (Scopus)
35 Downloads (Pure)

Prenucleation self-assembly and chiral discrimination mechanisms during solution crystallisation of racemic diprophylline

Brandel, C., Cartigny, Y., Coquerel, G., ter Horst, J. H. & Petit, S., 2 Nov 2016, In : Chemistry - A European Journal . 22, 45, p. 16103-16112 10 p.

Research output: Contribution to journalArticle

Open Access
File
7 Citations (Scopus)
26 Downloads (Pure)

Solid separation from a mixed suspension through electric-field-enhanced crystallization

Li, W., Radacsi, N., Kramer, H. J. M., van der Heijden, A. E. D. M. & ter Horst, J. H., 23 Dec 2016, In : Angewandte Chemie International Edition. 55, 52, p. 16088-16091 4 p.

Research output: Contribution to journalArticle

Open Access
File
3 Citations (Scopus)
77 Downloads (Pure)

Solvates, salts, and cocrystals: a proposal for a feasible classification system

Grothe, E., Meekes, H., Vlieg, E., Ter Horst, J. H. & De Gelder, R., 1 Jun 2016, In : Crystal Growth and Design . 16, 6, p. 3237-3243 7 p.

Research output: Contribution to journalArticle

Open Access
File
62 Citations (Scopus)
28 Downloads (Pure)
2015

Attrition-enhanced deracemization of NaClO3: comparison between ultrasonic and abrasive grinding

Xiouras, C., Van Aeken, J., Panis, J., Ter Horst, J. H., Van Gerven, T. & Stefanidis, G. D., 4 Nov 2015, In : Crystal Growth and Design . 15, 11, p. 5476-5484 9 p.

Research output: Contribution to journalArticle

Open Access
File
25 Citations (Scopus)
53 Downloads (Pure)

Fundamentals of industrial crystallization

Ter Horst, J. H., Schmidt, C. & Ulrich, J., 2015, Handbook of Crystal Growth. Nishinaga, T. & Rudolph, P. (eds.). 2015 ed. Amsterdam, Vol. II. p. 1317-1349 33 p.

Research output: Chapter in Book/Report/Conference proceedingChapter (peer-reviewed)

16 Citations (Scopus)

Measuring induction times and crystal nucleation rates

Brandel, C. & ter Horst, J. H., 2015, In : Faraday Discussions. 179, p. 199-214 16 p.

Research output: Contribution to journalArticle

Open Access
File
55 Citations (Scopus)
221 Downloads (Pure)

Nucleation in complex multi-component and multi-phase systems: General discussion

Price, S., Rimez, B., Sun, W., Peters, B., Christenson, H., Hughes, C., Sun, C. C., Veesler, S., Pan, H., Brandel, C., Biscans, B., Meekes, H., Rosbottom, I., Roth, W. J., Seton, L., Taulelle, F., Black, S., Threlfall, T., Vekilov, P., Poornachary, S. & 27 others, Diemand, J., Toroz, D., Salvalaglio, M., Tipduangta, P., Sefcik, J., Booth, S., Rasmuson, A., Janbon, S., Ter Horst, J., Simone, E., Hammond, R., Bertran, C. A., Vetter, T., Sear, R., De Yoreo, J., Harris, K., Ristic, R., Kavanagh, A., Roberts, K., Breynaert, E., Myerson, A., Coquerel, G., Wu, D., Cölfen, H., Cuppen, H., Smets, M. & Wu, D. T., 1 Jul 2015, In : Faraday Discussions. 179, p. 503-542 40 p.

Research output: Contribution to journalComment/debate

Solubility determination from clear points upon solvent addition

Reus, M. A., Van Der Heijden, A. E. D. M. & Ter Horst, J. H., 3 Aug 2015, In : Organic Process Research and Development. 19, 8, p. 1004-1011 8 p.

Research output: Contribution to journalArticle

Open Access
File
12 Citations (Scopus)
65 Downloads (Pure)

Solvent and additive interactions as determinants in the nucleation pathway: general discussion

Sun, C. C., Sun, W., Price, S., Hughes, C., Ter Horst, J., Veesler, S., Lewtas, K., Myerson, A., Pan, H., Coquerel, G., Van Den Ende, J., Meekes, H., Mazzotti, M., Rosbottom, I., Taulelle, F., Black, S., Mackenzie, A., Janbon, S., Vekilov, P., Threlfall, T. & 26 others, Turner, T., Back, K., Cuppen, H., Toroz, D., Sefcik, J., Lovelock, J., Hammond, R., Candoni, N., Simone, E., Ward, M., Bertran, C. A., Vetter, T., Sear, R., De Yoreo, J., Davey, R., Anwar, J., Santiso, E., Wu, D. T., Roberts, K., Peters, B., Schroeder, S., Jones, F., Rasmuson, A., Cölfen, H., Zeglinski, J. & Salvalaglio, M., 1 Jul 2015, In : Faraday Discussions. 179, p. 383-420 38 p.

Research output: Contribution to journalComment/debate

8 Citations (Scopus)

Time and space resolved methods: General discussion

Sun, W., Booth, S., Myerson, A., Hughes, C., Pan, H., Coquerel, G., Brandel, C., Meekes, H., Mazzotti, M., Fabian, L., Black, S., Vekilov, P., Back, K., Toroz, D., Lovelock, J., Sefcik, J., Rasmuson, A., Breynaert, E., Sear, R., Hammond, R. & 13 others, Ward, M., Threlfall, T., De Yoreo, J., Davey, R., Ristic, R., Lewtas, K., Roberts, K., Hare, A., Gich, M., Cölfen, H., Likhatskiy, M., Ter Horst, J. & Sommerdijk, N., 1 Jul 2015, In : Faraday Discussions. 179, p. 247-267 21 p.

Research output: Contribution to journalComment/debate

4 Citations (Scopus)
2014

A thermodynamic based approach on the investigation of a diflunisal pharmaceutical co-crystal with improved intrinsic dissolution rate

Évora, A. O. L., Castro, R. A. E., Maria, T. M. R., Silva, M. R., Ter Horst, J. H., Canotilho, J. & Eusébio, M. E. S., 15 May 2014, In : International Journal of Pharmaceutics. 466, 1-2, p. 68-75 8 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Concomitant crystallization for in situ encapsulation of organic materials

Reus, M. A., Hoetmer, G., van der Heijden, A. E. D. M. & ter Horst, J. H., 1 Jun 2014, In : Chemical Engineering and Processing: Process Intensification. 80, p. 11-20 10 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Polymorphism control through a single nucleation event

Kulkarni, S. A., Meekes, H. & Ter Horst, J. H., 5 Mar 2014, In : Crystal Growth and Design . 14, 3, p. 1493-1499 7 p.

Research output: Contribution to journalArticle

26 Citations (Scopus)

Revealing the roles of desolvation and molecular self-assembly in crystal nucleation from solution: benzoic and p -aminobenzoic acids

Sullivan, R. A., Davey, R. J., Sadiq, G., Dent, G., Back, K. R., Ter Horst, J. H., Toroz, D. & Hammond, R. B., 7 May 2014, In : Crystal Growth and Design . 14, 5, p. 2689-2696 8 p.

Research output: Contribution to journalArticle

63 Citations (Scopus)

Self-association during heterogeneous nucleation onto well-defined templates

Kulkarni, S. A., Weber, C. C., Myerson, A. S. & Ter Horst, J. H., 21 Oct 2014, In : Langmuir. 30, 41, p. 12368-12375 8 p.

Research output: Contribution to journalArticle

Open Access
File
15 Citations (Scopus)
117 Downloads (Pure)

Template-induced nucleation of isonicotinamide polymorphs

Caridi, A., Kulkarni, S. A., Di Profio, G., Curcio, E. & Ter Horst, J. H., 5 Mar 2014, In : Crystal Growth and Design . 14, 3, p. 1135-1141 7 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)