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Personal profile

Personal Statement

I completed my PhD developing anticancer silk nanomedicines in 2019 under the supervision of Dr Philipp Seib and Dr Blair Johnston. I was subsequently awarded the EPSRC Doctoral Prize to continue my research under the mentorship of Professor Alastair Florence. Now hosted by the EPSRC CMAC Future Manufacturing Research Hub, the central aim of my research is to tune silk nanomedicine manufacturing to enhance healthcare performance.

Research Interests

Nanomedicine, biomaterials, drug delivery

Education/Academic qualification

Doctor of Philosophy, Strathclyde Institute Of Pharmacy And Biomedical Sciences

1 Oct 201517 May 2019

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Silk Medicine & Life Sciences
Nanoparticles Medicine & Life Sciences
Macrophages Chemical Compounds
Nanomedicine Medicine & Life Sciences
Fibroins Medicine & Life Sciences
Microfluidics Medicine & Life Sciences
Biocompatible Materials Medicine & Life Sciences
Pharmaceutical Preparations Medicine & Life Sciences

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Projects 2015 2019

Research Output 2017 2019

2 Citations (Scopus)
16 Downloads (Pure)

Microfluidic-assisted silk nanoparticle tuning

Wongpinyochit, T., Totten, J. D., Johnston, B. F. & Seib, F. P., 30 Jan 2019, In : Nanoscale Advances. 1, 2, p. 873-883 11 p.

Research output: Contribution to journalArticle

Open Access
Inhibitory Concentration 50
3 Citations (Scopus)
9 Downloads (Pure)

PEGylation-dependent metabolic rewiring of macrophages with silk fibroin nanoparticles

Totten, J. D., Wongpinyochit, T., Carrola, J., Duarte, I. F. & Seib, F. P., 24 Apr 2019, In : ACS Applied Materials and Interfaces. 11, 16, p. 14515-14525 11 p.

Research output: Contribution to journalArticle

Open Access


Silk fibroin nanoparticles : in vitro performance of a putative anticancer nanomedicine

Author: Totten, J., 1 Apr 2019

Supervisor: Seib, P. (Supervisor) & Johnston, B. (Supervisor)

Student thesis: Doctoral Thesis


EPSRC Doctoral Prize

John Totten (Recipient), Jun 2019

Prize: Prize (including medals and awards)

Activities 2019 2019

  • 1 Journal peer review

International Journal of Nanomedicine (Journal)

John Totten (Peer reviewer)
Jun 2019

Activity: Publication peer-review and editorial work typesJournal peer review