19972020

Research output per year

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Personal profile

Research Interests

Our research expertise is in particle engineering and nanostructured materials, with focus on design of novel particulate products and efficient processes for their manufacturing, across a wide range of applications from nucleation and crystallisation, to protein and peptide self-assembly, to organic gels and nanocomposites.

Our research in pharmaceutical manufacturing aligned with CMAC seeks to enhance access to medicines by increasing quality and reducing costs with the aim improving people’s health and wellbeing.

We develop experimental workflows for product and process development of particulate systems for pharmaceutical applications to obtain better control of critical quality attributes in medicines manufacturing.

We also develop new methods for extracting valuable real time information from process analytical tools such as imaging and scattering/backscattering to enable intelligent decision support for monitoring and control of particulate systems and processes, including fouling detection and accurate quantitative estimates of particle shape and size distributions from in situ measurements.   

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Projects

Research Output

Chain-end modifications and sequence arrangements of antimicrobial peptoids for mediating activity and nano-assembly

Hasan, A., Saxena, V., Castelletto, V., Zimbitas, G., Seitsonen, J., Ruokolainen, J., Pandey, L. M., Sefcik, J., Hamley, I. W. & Lau, K. H. A., 21 May 2020, In : Frontiers in Chemistry. 8, 12 p., 416.

Research output: Contribution to journalArticle

Open Access
File
  • 1 Downloads (Pure)

    Interfacial concentration effect facilitates heterogeneous nucleation from solution

    McKechnie, D., Anker, S., Zahid, S., Mulheran, P. A., Sefcik, J. & Johnston, K., 19 Mar 2020, In : Journal of Physical Chemistry Letters. 11, 6, p. 2263-2271 9 p.

    Research output: Contribution to journalArticle

    Open Access
    File
  • 2 Downloads (Pure)

    Thesis

    Batch to continuous organic salt crystallisation : model based design

    Author: McGinty, J., 6 Oct 2017

    Supervisor: Sefcik, J. (Supervisor) & Florence, A. (Supervisor)

    Student thesis: Doctoral Thesis

    Combined wet milling crystallisation methods for particle engineering

    Author: Ahmed, B., 9 Oct 2019

    Supervisor: Florence, A. (Supervisor) & Sefcik, J. (Supervisor)

    Student thesis: Doctoral Thesis

    Activities

    8th World Congress on Particle Technology

    Carla Sofia Ferreira (Speaker), Yi-Chieh Chen (Participant), Jan Sefcik (Participant)
    24 Apr 2018

    Activity: Participating in or organising an event typesParticipation in conference

    Network Plus: Industrial Systems in the Digital Age Conference 2017

    Javier Cardona (Participant), Carla Sofia Ferreira (Participant), John McGinty (Participant), Andrew Hamilton (Participant), Okpeafoh Agimelen (Participant), Alison Cleary (Participant), Yi-Chieh Chen (Speaker), Jan Sefcik (Participant), Walter Michie (Participant), Ivan Andonovic (Participant), Christos Tachtatzis (Participant)
    20 Jun 201721 Jun 2017

    Activity: Participating in or organising an event typesParticipation in conference