Projects per year
Personal profile
Research Interests
Our research expertise is in particle engineering and nanostructured materials, with focus on design of novel particulate products and efficient processes for their manufacturing, across a wide range of applications from nucleation and crystallisation, to protein and peptide self-assembly, to organic gels and nanocomposites.
Our research in pharmaceutical manufacturing aligned with CMAC seeks to enhance access to medicines by increasing quality and reducing costs with the aim improving people’s health and wellbeing.
We develop experimental workflows for product and process development of particulate systems for pharmaceutical applications to obtain better control of critical quality attributes in medicines manufacturing.
We also develop new methods for extracting valuable real time information from process analytical tools such as imaging and scattering/backscattering to enable intelligent decision support for monitoring and control of particulate systems and processes, including fouling detection and accurate quantitative estimates of particle shape and size distributions from in situ measurements.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Collaborations and top research areas from the last five years
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Effects of mechanical impact and turbulent flow on secondary nucleation
1/10/22 → 30/09/26
Project: Research - Studentship
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Nucleation and growth kinetics of sodium chloride crystallization from water and deuterium oxide
Flannigan, J. M., MacIver, D., Jolliffe, H., Haw, M. D. & Sefcik, J., 18 Sept 2023, In: Crystals. 13, 9, 28 p., 1388.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Downloads (Pure) -
Digital process design to define and deliver pharmaceutical particle attributes
Urwin, S. J., Chong, M. W. S., Li, W., McGinty, J., Mehta, B., Ottoboni, S., Pathan, M., Prasad, E., Robertson, M., McGowan, M., al-Attili, M., Gramadnikova, E., Siddique, M., Houson, I., Feilden, H., Benyahia, B., Brown, C. J., Halbert, G. W., Johnston, B., Nordon, A., & 4 others , 31 Aug 2023, In: Chemical Engineering Research and Design. 196, p. 726-749 24 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile6 Downloads (Pure)
Datasets
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Data for: "Tuning Interfacial Concentration Enhancement through Dispersion Interactions to Facilitate Heterogeneous Nucleation"
McKechnie, D. (Creator), Mulheran, P. (Supervisor), Sefcik, J. (Supervisor) & Johnston, K. (Supervisor), University of Strathclyde, 2 Sept 2022
DOI: 10.15129/8d54c68e-69a6-4215-8a4c-d0141d3f2baf
Dataset
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Data for: "Nucleation and growth in isothermal crystallization of Sodium Chloride from Water and Deuterium Oxide"
Haw, M. (Supervisor), Flannigan, J. (Creator) & Sefcik, J. (Supervisor), University of Strathclyde, 15 Sept 2023
DOI: 10.15129/6bccdd95-1767-4245-88a0-6fa97fb43829
Dataset
Activities
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Evaluation of methods for particle characterisation from in-line imaging and chord length distribution measurements
Christopher Boyle (Speaker), Javier Cardona Amengual (Contributor), Jan Sefcik (Contributor), Cameron Brown (Contributor), Neda Nazemifard (Contributor), Vaclav Svoboda (Contributor), Christopher L. Burcham (Contributor), Jan-Sebastiaan Uyttersprot (Contributor) & Francesca Perciballi (Contributor)
17 Nov 2022Activity: Talk or presentation types › Oral presentation
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Evaluation of Deep Learning methods for particle characterisation from in-line imaging and chord length distribution measurements
Christopher Boyle (Speaker), Cameron Brown (Contributor), Jan Sefcik (Contributor) & Javier Cardona Amengual (Contributor)
18 Sept 2022Activity: Talk or presentation types › Oral presentation