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James Thompson


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Integrin alpha6 Chemical Compounds
Integrin alpha Chains Medicine & Life Sciences
Betaine Chemical Compounds
Methylation Chemical Compounds
Pharmacokinetics Chemical Compounds
Cell adhesion Chemical Compounds
Ammonium Compounds Chemical Compounds
Cell Adhesion Medicine & Life Sciences

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Research Output 2019 2019

Profile of a highly selective quaternized pyrrolidine betaine αvβ6 integrin inhibitor - (3S)-3-(3-(3,5-Dimethyl-1H-pyrazol-1-yl)phenyl)-4-((1S and 1R,3R)-1-methyl-3-(2- (5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethyl)pyrrolidin-1-ium-1-yl)butanoate synthesized by stereoselective methylation

Barrett, T. N., Taylor, J. A., Barker, D., Procopiou, P. A., Thompson, J. D. F., Barrett, J., Le, J., Lynn, S. M., Pogany, P., Pratley, C., Pritchard, J. M., Roper, J. A., Rowedder, J. E., Slack, R. J., Vitulli, G., Macdonald, S. J. F. & Kerr, W. J., 22 Aug 2019, In : Journal of Medicinal Chemistry. 62, 16, p. 7543-7556 14 p.

Research output: Contribution to journalArticle

Integrin alpha6
Integrin alpha Chains