Research output per year
Research output per year
- 1 - 50 out of 108 results
Search results
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2023
Quantification of drug metabolising enzymes and transporter proteins in the paediatric duodenum via LC-MS/MS proteomics using a QconCAT technique
Goelen, J., Farrell, G., McGeehan, J., Titman, C. M., Rattray, N. J. W., Johnson, T. N., Horniblow, R. D. & Batchelor, H. K., 31 Oct 2023, In: European Journal of Pharmaceutics and Biopharmaceutics. 191, p. 68-77 10 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile8 Downloads (Pure) -
Colour of medicines and children's acceptability? A systematic literature review of children's perceptions about colours of oral dosage forms
Alessandrini, E., Gonakova, M., Batchelor, H., Gizurarson, S., Iurian, S., Klein, S., Schaufelberger, D., Turner, R., Walsh, J. & Tuleu, C., 20 Jul 2023, In: Pharmaceutics. 15, 7, 19 p., 1992.Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Downloads (Pure) -
Optimizing expert and patient input in pediatric trial design: lessons learned and recommendations from a collaboration between conect4children and European Patient‐CEntric ClinicAl TRial PLatforms
Dhaenens, B. A. E., Mahler, F., Batchelor, H., Dicks, P., Gaillard, S., Nafria, B., Kopp‐Schneider, A., Ribeiro, MA., Schwab, M., Sparber‐Sauer, M., Leubner, J., de Wildt, S. N. & Oostenbrink, R., 30 Jun 2023, In: Clinical and Translational Science. 16, 8, p. 1458-1468 11 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Downloads (Pure) -
Integration of biorelevant pediatric dissolution methodology into PBPK modeling to predict in vivo performance and bioequivalence of generic drugs in pediatric populations: a carbamazepine case study
Pawar, G., Wu, F., Zhao, L., Fang, L., Burckart, G. J., Feng, K., Mousa, Y. M., Al Shoyaib, A., Jones, M-C. & Batchelor, H. K., 29 Jun 2023, In: AAPS Journal. 25, 4, 67.Research output: Contribution to journal › Article › peer-review
Open AccessFile4 Downloads (Pure) -
Use of in vitro Dynamic Colon Model (DCM) to inform a physiologically based biopharmaceutic model (PBBM) to predict the in vivo performance of a modified-release formulation of theophylline
Stamatopoulos, K., O’Farrell, C., Simmons, M. J. H., Batchelor, H. K. & Mistry, N., 9 Mar 2023, In: Pharmaceutics. 15, 3, 15 p., 882.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)5 Downloads (Pure) -
The pipeline for drugs for control and elimination of neglected tropical diseases: 1. Anti-infective drugs for regulatory registration
Pfarr, K. M., Krome, A. K., Al-Obaidi, I., Batchelor, H., Vaillant, M., Hoerauf, A., Opoku, N. O. & Kuesel, A. C., 1 Mar 2023, In: Parasites and Vectors. 16, 1, 17 p., 82.Research output: Contribution to journal › Review article › peer-review
Open AccessFile1 Citation (Scopus)7 Downloads (Pure) -
Solid lipid nanoparticles and nanostructured lipid carriers of dual functionality at emulsion interfaces. Part II: active carrying/delivery functionality
Sakellari, G. I., Zafeiri, I., Batchelor, H. & Spyropoulos, F., 20 Feb 2023, In: Colloids and Surfaces A: Physicochemical and Engineering Aspects . 659, 14 p., 130787.Research output: Contribution to journal › Article › peer-review
Open AccessFile7 Downloads (Pure) -
2022
Drugs for neglected tropical diseases: availability of age-appropriate oral formulations for young children
Al-Obaidi, I., Krome, A. K., Wagner, K. G., Pfarr, K., Kuesel, A. C. & Batchelor, H. K., 12 Dec 2022, In: Parasites and Vectors. 15, 1, 22 p., 462.Research output: Contribution to journal › Review article › peer-review
Open AccessFile5 Downloads (Pure) -
Solid lipid nanoparticles and nanostructured lipid carriers of dual functionality at emulsion interfaces. Part I: Pickering stabilisation functionality
Sakellari, G. I., Zafeiri, I., Batchelor, H. & Spyropoulos, F., 5 Dec 2022, In: Colloids and Surfaces A: Physicochemical and Engineering Aspects . 654, 12 p., 130135.Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Citations (Scopus)12 Downloads (Pure) -
Development of a digital twin of a tablet that mimics a real solid dosage form: differences in the dissolution profile in conventional mini-USP II and a biorelevant colon model
Schütt, M., Stamatopoulos, K., Batchelor, H. K., Simmons, M. J. H. & Alexiadis, A., 1 Dec 2022, In: European Journal of Pharmaceutical Sciences. 179, 13 p., 106310.Research output: Contribution to journal › Article › peer-review
Open AccessFile6 Downloads (Pure) -
Solubility measurement of poorly soluble drugs in fasted state simulated intestinal fluid
McKinnon, Z., Batchelor, H., Khadra, I. & Halbert, G., 2 Nov 2022, In: British Journal of Pharmacy. 7, 2, 2 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile24 Downloads (Pure) -
The effect of biorelevant hydrodynamic conditions on drug dissolution from extended-release tablets in the dynamic colon model
O’Farrell, C., Simmons, M. J. H., Batchelor, H. K. & Stamatopoulos, K., 14 Oct 2022, In: Pharmaceutics. 14, 10, 2193.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)5 Downloads (Pure) -
Correction: Schütt et al. Simulating the hydrodynamic conditions of the human ascending colon: a digital twin of the dynamic colon model. Pharmaceutics 2022, 14, 184
Schütt, M., O'Farrell, C., Stamatopoulos, K., Hoad, C. L., Marciani, L., Sulaiman, S., Simmons, M. J. H., Batchelor, H. K. & Alexiadis, A., 4 Jul 2022, In: Pharmaceutics. 14, 7, 2 p., 1402.Research output: Contribution to journal › Comment/debate › peer-review
Open AccessFile3 Downloads (Pure) -
Application of a physiologically based pharmacokinetic model to predict cefazolin and cefuroxime disposition in obese pregnant women undergoing caesarean section
Alrammaal, H. H., Abduljalil, K., Hodgetts Morton, V., Morris, R. K., Marriott, J. F., Chong, H. P. & Batchelor, H. K., 30 May 2022, In: Pharmaceutics. 14, 6, 23 p., 1162.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Citations (Scopus)1 Downloads (Pure) -
Practical and operational considerations related to paediatric oral drug formulation: an industry survey
Van der Veken, M., Brouwers, J., Budts, V., Lauwerys, L., Pathak, S. M., Batchelor, H. & Augustijns, P., 25 Apr 2022, In: International journal of pharmaceutics. 618, 11 p., 121670.Research output: Contribution to journal › Article › peer-review
Open AccessFile7 Citations (Scopus)9 Downloads (Pure) -
Biopharmaceutic classification system
Batchelor, H. & Flanagan, T., 28 Jan 2022, Biopharmaceutics: From Fundamentals to Industrial Practice. Batchelor, H. (ed.). p. 135-146 12 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter
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Biopharmaceutics of topical and transdermal formulations
Batchelor, H., 28 Jan 2022, Biopharmaceutics: From Fundamentals to Industrial Practice. Chichester, p. 265-276 12 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter
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Dissolution
Batchelor, H. & Butler, J., 28 Jan 2022, Biopharmaceutics: From Fundamentals to Industrial Practice. Chichester, p. 73-98 26 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter
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Impact of the microbiome on oral biopharmaceutics
McCoubrey, L. E., Batchelor, H., Basit, A. W., Gaisford, S. & Orlu, M., 28 Jan 2022, Biopharmaceutics: from Fundamentals to Industrial Practice. Batchelor, H. (ed.). Chichester, UK, p. 277-295 19 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter
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Solubility
Batchelor, H., 28 Jan 2022, Biopharmaceutics: From Fundamentals to Industrial Practice. Chichester, p. 39-50 12 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter
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Biopharmaceutics: From Fundamentals to Industrial Practice
Batchelor, H., 13 Jan 2022, Chichester. 298 p.Research output: Book/Report › Book
1 Citation (Scopus) -
Simulating the hydrodynamic conditions of the human ascending colon: a digital twin of the dynamic colon model
Schütt, M., O’Farrell, C., Stamatopoulos, K., Hoad, C. L., Marciani, L., Sulaiman, S., Simmons, M. J. H., Batchelor, H. K. & Alexiadis, A., 13 Jan 2022, In: Pharmaceutics. 14, 1, 23 p., 184.Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Citations (Scopus)11 Downloads (Pure) -
2021
In vitro models to evaluate ingestible devices: present status and current trends
O’Farrell, C., Stamatopoulos, K., Simmons, M. & Batchelor, H., Nov 2021, In: Advanced Drug Delivery Reviews. 178, 109 p., 113924.Research output: Contribution to journal › Article › peer-review
Open AccessFile6 Citations (Scopus)23 Downloads (Pure) -
In vivo models to evaluate ingestible devices: present status and current trends
Stamatopoulos, K., O’Farrell, C., Simmons, M. & Batchelor, H., 31 Oct 2021, In: Advanced Drug Delivery Reviews. 177, 24 p., 113915.Research output: Contribution to journal › Article › peer-review
Open AccessFile7 Citations (Scopus)6 Downloads (Pure) -
Quantification of fluid volume and distribution in the paediatric colon via Magnetic Resonance Imaging
Goelen, J., Alexander, B., Eranga Wijesinghe, H., Evans, E., Pawar, G., Horniblow, R. D. & Batchelor, H. K., 19 Oct 2021, In: Pharmaceutics. 13, 10, 15 p., 1729.Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Citations (Scopus)27 Downloads (Pure) -
Luminal fluid motion inside an in vitro dissolution model of the human ascending colon assessed using magnetic resonance imaging
O’Farrell, C., Hoad, C. L., Stamatopoulos, K., Marciani, L., Sulaiman, S., Simmons, M. J. H. & Batchelor, H. K., 23 Sept 2021, In: Pharmaceutics. 13, 10, 26 p., 1545.Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Citations (Scopus)2 Downloads (Pure) -
Formulation design, production and characterisation of solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC) for the encapsulation of a model hydrophobic active
Sakellari, G. I., Zafeiri, I., Batchelor, H. & Spyropoulos, F., 6 Sept 2021, In: Food Hydrocolloids for Health. 1, 18 p., 100024.Research output: Contribution to journal › Article › peer-review
Open AccessFile18 Citations (Scopus)5 Downloads (Pure) -
Path towards efficient paediatric formulation development based on partnering with clinical pharmacologists and clinicians, a conect4children expert group white paper
Walsh, J., Schaufelberger, D., Iurian, S., Klein, S., Batchelor, H., Turner, R., Gizurarson, S., Boltri, L., Alessandrini, E. & Tuleu, C., 14 Aug 2021, (E-pub ahead of print) In: British Journal of Clinical Pharmacology . 88, 12, p. 5034-5051 18 p.Research output: Contribution to journal › Review article › peer-review
Open AccessFile8 Citations (Scopus)34 Downloads (Pure) -
Modelling and simulation of the drug release from a solid dosage form in the human ascending colon: the influence of different motility patterns and fluid viscosities
Schütt, M., Stamatopoulos, K., Batchelor, H. K., Simmons, M. J. H. & Alexiadis, A., 10 Jun 2021, In: Pharmaceutics. 13, 6, 26 p., 859.Research output: Contribution to journal › Article › peer-review
Open AccessFile7 Citations (Scopus)2 Downloads (Pure) -
Current challenges and future perspectives in oral absorption research: an opinion of the UNGAP network
Vinarov, Z., Abrahamsson, B., Artursson, P., Batchelor, H., Berben, P., Bernkop-Schnürch, A., Butler, J., Ceulemans, J., Davies, N., Dupont, D., Flaten, G. E., Fotaki, N., Griffin, B. T., Jannin, V., Keemink, J., Kesisoglou, F., Koziolek, M., Kuentz, M., Mackie, A., Meléndez-Martínez, A. J., & 16 others, 30 Apr 2021, In: Advanced Drug Delivery Reviews. 171, p. 289-331 43 p.Research output: Contribution to journal › Review article › peer-review
Open AccessFile58 Citations (Scopus)6 Downloads (Pure) -
Development of a pediatric relative bioavailability/bioequivalence database and identification of putative risk factors associated with evaluation of pediatric oral products
Pawar, G., Wu, F., Zhao, L., Fang, L., Burckhart, G. J., Feng, K., Mousa, Y. M., Neuman, F. & Batchelor, H. K., 21 Apr 2021, In: AAPS Journal. 23, 12 p., 57.Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Citations (Scopus)22 Downloads (Pure) -
The virtual physiological human gets nerves! How to account for the action of the nervous system in multiphysics simulations of human organs
Alexiadis, A., Simmons, M. J. H., Stamatopoulos, K., Batchelor, H. K. & Moulitsas, I., 14 Apr 2021, In: Journal of the Royal Society, Interface. 18, 177, 9 p., 20201024.Research output: Contribution to journal › Article › peer-review
Open AccessFile5 Citations (Scopus)2 Downloads (Pure) -
Tribology provides an in vitro tool that correlated to in vivo sensory data on the mouthfeel of coated tablets
Hofmanová, J. K., Mason, J. & Batchelor, H. K., 15 Mar 2021, In: International Journal of Pharmaceutics. 597, 120323.Research output: Contribution to journal › Article › peer-review
Open AccessFile6 Citations (Scopus)17 Downloads (Pure) -
Publisher correction: The duality between particle methods and artificial neural networks
Alexiadis, A., Simmons, M. J. H., Stamatopoulos, K., Batchelor, H. K. & Moulitsas, I., 5 Mar 2021, In: Scientific Reports. 11, 1 p., 5726.Research output: Contribution to journal › Comment/debate › peer-review
Open AccessFile4 Downloads (Pure) -
Prophylactic perioperative cefuroxime levels in plasma and adipose tissue at the time of caesarean section (C-LACE): a protocol for a pilot experimental, prospective study with non-probability sampling to determine interpatient variability
Alrammaal, H. H., Batchelor, H. K., Chong, H. P., Hodgetts Morton, V. & Morris, R. K., 18 Feb 2021, In: Pilot and Feasibility Studies. 7, 8 p., 54.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Citations (Scopus)10 Downloads (Pure) -
Sporopollenin exine microcapsules as potential intestinal delivery system of probiotics
Stamatopoulos, K., Kafourou, V., Batchelor, H. K. & Konteles, S. J., 18 Feb 2021, In: Small. 17, 7, 12 p., 2004573.Research output: Contribution to journal › Article › peer-review
Open AccessFile18 Citations (Scopus)2 Downloads (Pure) -
Characterisation of fasted state gastric and intestinal fluids collected from children
Pawar, G., Papadatou-Soulou, E., Mason, J., Muhammed, R., Watson, A., Cotter, C., Abdullah, M., Harrad, S., Mackie, C., Arien, T., Inghelbrecht, S. & Batchelor, H., 31 Jan 2021, In: European Journal of Pharmaceutics and Biopharmaceutics. 158, p. 156-165 10 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile5 Citations (Scopus)63 Downloads (Pure) -
Determination of healthcare resource and cost implications of using alternative sodium valproate formulations in the treatment of epilepsy in children in England: a retrospective database review
Batchelor, H., 31 Jan 2021, In: European Journal of Pharmaceutics and Biopharmaceutics . 158, p. 365-370 6 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)4 Downloads (Pure) -
An introduction to biopharmaceutics
Batchelor, H., 1 Jan 2021, Biopharmaceutics: From Fundamentals to Industrial Practice. 1st ed. Chichester, UK ; Hoboken, NJ, p. 1-8 8 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter
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Introduction to biopharmaceutics measures
Batchelor, H. & Gershkovich, P., 1 Jan 2021, Biopharmaceutics: From Fundamentals to Industrial Practice. 1st ed. Chichester, UK ; Hoboken, NJ, p. 31-38 8 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter
1 Citation (Scopus) -
2020
A review of in vitro and in vivo methods and their correlations to assess mouthfeel of solid oral dosage forms
Asiri, A., Hofmanová, J. & Batchelor, H., 26 Dec 2020, (E-pub ahead of print) In: Drug Discovery Today.Research output: Contribution to journal › Review article › peer-review
Open AccessFile5 Citations (Scopus)11 Downloads (Pure) -
The duality between particle methods and artificial neural networks
Alexiadis, A., Simmons, M. J. H., Stamatopoulos, K., Batchelor, H. K. & Moulitsas, I., 1 Dec 2020, In: Scientific Reports. 10, 1, 7 p., 16247.Research output: Contribution to journal › Article › peer-review
Open AccessFile7 Citations (Scopus)5 Downloads (Pure) -
Sensory attributes of coated tablets: developing a formal lexicon and sensory wheel
Hofmanová, J. K., Mason, J. & Batchelor, H. K., 30 Nov 2020, In: International Journal of Pharmaceutics. 590, 7 p., 119883.Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Citations (Scopus)5 Downloads (Pure) -
A novel oral syringe for dosing and administration of multiparticulate formulations: acceptability study in preschool and school children
Hofmanová, J. K., Bennett, J., Coupe, A., Bartlett, J. A., Monahan, A. & Batchelor, H. K., 25 Aug 2020, In: Pharmaceutics. 12, 9, 15 p., 806.Research output: Contribution to journal › Article › peer-review
Open AccessFile7 Citations (Scopus)13 Downloads (Pure) -
Sensory aspects of acceptability of bitter-flavoured 7.5 mm film-coated tablets in adults, preschool and school children
Hofmanová, J. K., Mason, J. & Batchelor, H. K., 30 Jul 2020, In: International Journal of Pharmaceutics. 585, 10 p., 119511.Research output: Contribution to journal › Article › peer-review
Open AccessFile5 Citations (Scopus)19 Downloads (Pure) -
Dynamic colon model (DCM): a cine-mri informed biorelevant in vitro model of the human proximal large intestine characterized by positron imaging techniques
Stamatopoulos, K., Karandikar, S., Goldstein, M., O’Farrell, C., Marciani, L., Sulaiman, S., Hoad, C. L., Simmons, M. J. H. & Batchelor, H. K., 13 Jul 2020, In: Pharmaceutics. 12, 7, 20 p., 659.Research output: Contribution to journal › Article › peer-review
Open AccessFile11 Citations (Scopus)6 Downloads (Pure) -
Modelling and simulation of the hydrodynamics and mixing profiles in the human proximal colon using Discrete Multiphysics
Schütt, M., Stamatopoulos, K., Simmons, M. J. H., Batchelor, H. K. & Alexiadis, A., 30 Jun 2020, In: Computers in Biology and Medicine. 121, 103819.Research output: Contribution to journal › Article › peer-review
Open AccessFile22 Citations (Scopus)2 Downloads (Pure) -
Impact of gastrointestinal physiology on drug absorption in special populations––An UNGAP review
Stillhart, C., Vučićević, K., Augustijns, P., Basit, A. W., Batchelor, H., Flanagan, T. R., Gesquiere, I., Greupink, R., Keszthelyi, D., Koskinen, M., Madla, C. M., Matthys, C., Miljuš, G., Mooij, M. G., Parrott, N., Ungell, A. L., de Wildt, S. N., Orlu, M., Klein, S. & Müllertz, A., 30 Apr 2020, In: European Journal of Pharmaceutical Sciences. 147, 28 p., 105280.Research output: Contribution to journal › Article › peer-review
Open AccessFile89 Citations (Scopus)4 Downloads (Pure) -
2019
Linking moisture induced variations in pharmaceutical primary powders to their tableting performance
Shinebaum, R., Gabbott, I., Reynolds, G. K., Batchelor, H. K. & Ingram, A., 14 Nov 2019, 2019 AIChE annual meeting proceedings. [S.I.], (AIChE Annual Meeting, Conference Proceedings; vol. 2019-November).Research output: Chapter in Book/Report/Conference proceeding › Conference contribution book
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Efficacy of perioperative cefuroxime as a prophylactic antibiotic in women requiring caesarean section: a systematic review
Alrammaal, H. H., Batchelor, H. K., Morris, R. K. & Chong, H. P., 1 Nov 2019, In: European Journal of Obstetrics and Gynecology and Reproductive Biology. 242, p. 71-78 8 p.Research output: Contribution to journal › Review article › peer-review
Open AccessFile4 Citations (Scopus)8 Downloads (Pure)