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  • United Kingdom

Accepting PhD Students

20052019
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Research Output 2005 2019

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Article
2019

CHC22 clathrin mediates traffic from early secretory compartments for human GLUT4 pathway biogenesis

Camus, S. M., Camus, M. D., Figueras-Novoa, C., Boncompain, G., Sadacca, L. A., Esk, C., Bigot, A., Gould, G. W., Kioumourtzoglou, D., Perez, F., Bryant, N. J., Mukherjee, S. & Brodsky, F. M., 9 Oct 2019, (Accepted/In press) In : Journal of Cell Biology. 52 p.

Research output: Contribution to journalArticle

Open Access
File
Clathrin
Facilitative Glucose Transport Proteins
Endoplasmic Reticulum
Secretory Pathway
Legionella pneumophila

GLUT4 expression and glucose transport in human induced pluripotent stem cell-derived cardiomyocytes

Bowman, P. R. T., Smith, G. L. & Gould, G. W., 25 Jul 2019, In : PLoS One. 14, 7, 16 p., e0217885.

Research output: Contribution to journalArticle

Open Access
File
Induced Pluripotent Stem Cells
Stem cells
Cardiac Myocytes
Insulin
Glucose

The deubiquitinating enzyme USP25 binds tankyrase and regulates trafficking of the facilitative glucose transporter GLUT4 in adipocytes

Sadler, J. B. A., Lamb, C. A., Welburn, C. R., Adamson, I. S., Kioumourtzoglou, D., Chi, N-W., Gould, G. W. & Bryant, N. J., 18 Mar 2019, In : Scientific Reports. 9, 7 p., 4710.

Research output: Contribution to journalArticle

Open Access
File
Tankyrases
Facilitative Glucose Transport Proteins
Adipocytes
Insulin
Ubiquitination
3 Downloads (Pure)

The human-specific and smooth muscle cell-enriched LncRNA SMILR promotes proliferation by regulating mitotic CENPF mRNA and drives cell-cycle progression which can be targeted to limit vascular remodeling

Mahmoud, A. D., Ballantyne, M. D., Miscianinov, V., Pinel, K., Hung, J., Scanlon, J. P., Iyinikkel, J., Kaczynski, J., Tavares, A. S., Bradshaw, A. C., Mills, N. L., Newby, D. E., Caporali, A., Gould, G. W., George, S. J., Ulitsky, I., Sluimer, J. C., Rodor, J. & Baker, A. H., 16 Aug 2019, In : Circulation Research. 125, 5, p. 535-551 17 p.

Research output: Contribution to journalArticle

Open Access
File
Smooth Muscle Myocytes
Cell Cycle
Messenger RNA
Vascular Smooth Muscle
Small Interfering RNA
2017
9 Citations (Scopus)

The trypanosome exocyst: a conserved structure revealing a new role in endocytosis

Boehm, C. M., Obado, S., Gadelha, C., Kaupisch, A., Manna, P. T., Gould, G. W., Munson, M., Chait, B. T., Rout, M. P. & Field, M. C., 23 Jan 2017, In : PLOS Pathogens. 13, 1, 25 p., e1006063.

Research output: Contribution to journalArticle

Open Access
File
Trypanosomiasis
Endocytosis
Immune Evasion
Antigenic Variation
Trypanosoma brucei brucei
2016
14 Citations (Scopus)
1 Downloads (Pure)

Protein kinase C phosphorylates AMP-activated protein kinase α1 Ser487

Heathcote, H. R., Mancini, S. J., Strembitska, A., Jamal, K., Reihill, J. A., Palmer, T. M., Gould, G. W. & Salt, I. P., 9 Dec 2016, In : Biochemical journal. 473, 24, p. 4681-4697 17 p.

Research output: Contribution to journalArticle

Open Access
File
AMP-Activated Protein Kinases
Phosphorylation
Protein Kinase C
Vascular Endothelial Growth Factor A
Endothelial cells
2015
6 Citations (Scopus)

Alternative routes to the cell surface underpin insulin-regulated membrane trafficking of GLUT4

Kioumourtzoglou, D., Pryor, P. R., Gould, G. W. & Bryant, N. J., 15 Jul 2015, In : Journal of Cell Science. 128, 14, p. 2423-2429 7 p.

Research output: Contribution to journalArticle

Open Access
File
Synaptogyrins
Insulin
Membranes
Adipocytes
Facilitative Glucose Transport Proteins
11 Citations (Scopus)

Characterization of VAMP isoforms in 3T3-L1 adipocytes: implications for GLUT4 trafficking

Sadler, J. B. A., Bryant, N. J. & Gould, G. W., 1 Feb 2015, In : Molecular Biology of the Cell. 26, 3, p. 530-536 7 p.

Research output: Contribution to journalArticle

Open Access
File
Adipocytes
Protein Isoforms
Vesicle-Associated Membrane Protein 2
Proteins
Vesicle-Associated Membrane Protein 3
1 Citation (Scopus)

mVps45 knockdown selectively modulates VAMP expression in 3T3-L1 adipocytes

Sadler, J. B. A., Roccisana, J., Virolainen, M., Bryant, N. J. & Gould, G. W., 24 Jun 2015, In : Communicative and Integrative Biology. 8, 3

Research output: Contribution to journalArticle

Open Access
File
Syntaxin 16
Vesicle-Associated Membrane Protein 2
glucose transporters
Facilitative Glucose Transport Proteins
adipocytes
2014
21 Citations (Scopus)

Insulin stimulates syntaxin4 SNARE complex assembly via a novel regulatory mechanism

Kioumourtzoglou, D., Gould, G. W. & Bryant, N. J., 30 Apr 2014, In : Molecular and Cellular Biology. 34, 7, p. 1271-1279 9 p.

Research output: Contribution to journalArticle

SNARE Proteins
Insulin
Cell Membrane
Adipocytes
Munc18 Proteins
2013
10 Citations (Scopus)

Sorting of GLUT4 into its insulin-sensitive store requires the Sec1/Munc18 protein mVps45

Roccisana, J., Sadler, J. B. A., Bryant, N. J. & Gould, G. W., 1 Aug 2013, In : Molecular Biology of the Cell. 24, 15, p. 2389-2397 9 p.

Research output: Contribution to journalArticle

Munc18 Proteins
Facilitative Glucose Transport Proteins
Protein Isoforms
Insulin
Adipocytes
22 Citations (Scopus)

Syntaxin 16 is a master recruitment factor for cytokinesis

Neto, H., Kaupisch, A., Collins, L. L. & Gould, G. W., 1 Dec 2013, In : Molecular Biology of the Cell. 24, 23, p. 3663-3674 12 p.

Research output: Contribution to journalArticle

Open Access
File
Syntaxin 16
Cytokinesis
Endosomal Sorting Complexes Required for Transport
SNARE Proteins
Endosomes
2012
26 Citations (Scopus)
341 Downloads (Pure)

Novel role for proteinase-activated receptor 2 (PAR2) in membrane trafficking of proteinase-activated receptor 4 (PAR4)

Cunningham, M. R., McIntosh, K. A., Pediani, J. D., Robben, J., Cooke, A. E., Nilsson, M., Gould, G. W., Mundell, S., Milligan, G. & Plevin, R., 11 May 2012, In : Journal of Biological Chemistry. 287, 20, p. 16656-16669 14 p.

Research output: Contribution to journalArticle

Open Access
File
Proteinase-Activated Receptors
PAR-2 Receptor
Membranes
Cell membranes
Chemical activation
2011
18 Citations (Scopus)

Tyrosine phosphorylation of Munc18c on residue 521 abrogates binding to Syntaxin 4

Aran, V., Bryant, N. J. & Gould, G. W., 6 May 2011, In : BMC Biochemistry. 12, 7 p., 19.

Research output: Contribution to journalArticle

Open Access
File
Qa-SNARE Proteins
Phosphorylation
Tyrosine
SNARE Proteins
Insulin
2008
67 Citations (Scopus)

Sequential Cyk-4 binding to ECT2 and FIP3 regulates cleavage furrow ingression and abscission during cytokinesis

Simon, G. C., Schonteich, E., Wu, C. C., Piekny, A., Ekiert, D., Yu, X., Gould, G. W., Glotzer, M. & Prekeris, R., 9 Jul 2008, In : EMBO Journal. 27, 13, p. 1791-1803 13 p.

Research output: Contribution to journalArticle

Telophase
Cytokinesis
pioglitazone
Endosomes
Recycling
2007
53 Citations (Scopus)

Role of endosomal Fab GTPases in cytokinesis

Yu, X., Prekeris, R. & Gould, G. W., 17 Jan 2007, In : European Journal of Cell Biology . 86, 1, p. 25-35 11 p.

Research output: Contribution to journalArticle

Cytokinesis
GTP Phosphohydrolases
Membranes
Telophase
RNA Interference
2006
66 Citations (Scopus)

Regulation of caveolar endocytosis by syntaxin 6-dependent delivery of membrane components to the cell surface

Choudhury, A., Marks, D. L., Proctor, K. M., Gould, G. W. & Pagano, R. E., 30 Apr 2006, In : Nature Cell Biology. 8, 4, p. 317-328 12 p.

Research output: Contribution to journalArticle

Qa-SNARE Proteins
Cellular Structures
Endocytosis
Caveolae
Membranes
2005
215 Citations (Scopus)

Rab11-FIP3 and FIP4 interact with Arf6 and the exocyst to control membrane traffic in cytokinesis

Fielding, A. B., Schonteich, E., Matheson, J., Wilson, G., Yu, X., Hickson, G. RX., Srivastava, S., Baldwin, S. A., Prekeris, R. & Gould, G. W., 5 Oct 2005, In : EMBO Journal. 24, 19, p. 3389-3399 11 p.

Research output: Contribution to journalArticle

Cytokinesis
Recycling
Endosomes
Membranes
Guanosine Triphosphate